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Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1534):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-137211
    Hydrocortisone-21-lysinate
    Hydrocortisone-21-lysinate is an active compound.
    Hydrocortisone-21-lysinate
  • HY-N15947
    Trifunctional sphingosine
    Trifunctional sphingosine is a clickable sphingoid base derivative. Trifunctional sphingosine can be used to study the biological function of sphingoid bases. Trifunctional lipids may overcome several challenges in interrogating lipid biology: their fast metabolism, their weak and transient (but functionally important) interactions with proteins, and the difficulty in tagging them without disturbing the cellular location.
    Trifunctional sphingosine
  • HY-118583A
    4-Fluoro phenibut hydrochloride
    4-Fluoro phenibut (β-(4-Fluorophenyl)-GABA) hydrochloride is a Gabapentinoid and is structurally similar to known nootropics.
    4-Fluoro phenibut hydrochloride
  • HY-111133
    LY 154045
    LY 154045 is an active compound.
    LY 154045
  • HY-B1708
    Nordefrin
    Nordefrin ((±)-Cobefri), a Norepinephrine (HY-13715) derivative, is a vasoconstrictor agent.
    Nordefrin
  • HY-145503
    Decanoyl-L-carnitine chloride
    Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism.
    Decanoyl-L-carnitine chloride
  • HY-119336
    Mebroqualone
    Mebroqualone is structurally categorized as a quinazolinone.
    Mebroqualone
  • HY-121155
    AD11
    AD11, a sulfonamide derivative, exhibits anticonvulsant potency in the rat.
    AD11
  • HY-161845
    Anticancer agent 240
    Anticancer agent 240 (compound 9b) is an 8-quinolinesulfonamide derivative with a cytotoxicity activity. Anticancer agent 240 shows inhibitory activity in Caco-2, SNB-19, A-549, and SKOV-3 cell line IC50 values of 0.26, 0.38, 0.40 and 4.16 μM.
    Anticancer agent 240
  • HY-135202
    Chloromethylketone methotrexate
    Chloromethylketone methotrexate is an active compound.
    Chloromethylketone methotrexate
  • HY-124889
    Dimethenamid
    Dimethenamid is an active compound.
    Dimethenamid
  • HY-124288
    PDK1/AurA-IN-1
    PDK1/AurA-IN-1 is an active compound.
    PDK1/AurA-IN-1
  • HY-10501B
    (Z)-SU14813
    (Z)-SU14813 is an analog of SU14813 (HY-10501). SU14813 is a multi-targeted receptor tyrosine kinases inhibitor with IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT.
    (Z)-SU14813
  • HY-122988
    Xenbucin
    Xenbucin is an active compound.
    Xenbucin
  • HY-W142120
    β-Asp-Phe methyl ester
    β-Asp-Phe methyl ester is an aspartic acid derivative.
    β-Asp-Phe methyl ester
  • HY-W011137
    (S)-4-Nitrophenyl 4-amino-2-((tert-butoxycarbonyl)amino)-4-oxobutanoate
    (S)-4-Nitrophenyl 4-amino-2-((tert-butoxycarbonyl)amino)-4-oxobutanoate is an asparagine derivative.
    (S)-4-Nitrophenyl 4-amino-2-((tert-butoxycarbonyl)amino)-4-oxobutanoate
  • HY-131805A
    3'-O-Ac-dGTP sodium
    3'-O-Ac-dGTP sodium is an acetylated derivative of the nucleoside triphosphate 2'-deoxyguanosine-5'-triphosphate.
    3'-O-Ac-dGTP sodium
  • HY-167919
    1-(1-Adamantyl)-3-butyl-2-thiourea
    1-(1-Adamantyl)-3-butyl-2-thiourea is a compound with antiviral activity, demonstrating efficacy against various viral pathogens; 1-(1-Adamantyl)-3-butyl-2-thiourea serves as a potential therapeutic agent in the treatment of viral infections.
    1-(1-Adamantyl)-3-butyl-2-thiourea
  • HY-158805
    4-Methoxy-α-pyrrolidinopropiophenone tosylate
    4-Methoxy-α-pyrrolidinopropiophenone (4'-MeO-α-ppp) tosylate is a biomolecule.
    4-Methoxy-α-pyrrolidinopropiophenone tosylate
  • HY-118719
    Esterbut-6
    Esterbut-6 is an active compound.
    Esterbut-6