2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1533):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-173542
    Progesterone-3-biotinyl Photoaffinity Probe
    Progesterone-3-biotinyl Photoaffinity Probe is a compound containing active progesterone (HY-N0437). Progesterone-3-biotinyl Photoaffinity Probe can be used in the research of mechanisms related to sperm activation.
    Progesterone-3-biotinyl Photoaffinity Probe
  • HY-131721
    14,15-EET-SI
    14,15-EET-SI is a sulfonimide (SI) analog metabolized from 14,15-EET, which is also an effective mitogen. 14,15-EET-SI can stimulate the incorporation of [3H] thymidine, activate pp60c-src and initiate the tyrosine kinase cascade, mediating their mitotic effects. Additionally, 14,15-EET-SI can increase cell proliferation as well as the expression of c-fos and egr-1 mRNA.
    14,15-EET-SI
  • HY-176218
    TTTE
    TTTE is a sulfone bischalcone derivative. TTTE has major anti-necrotic, anti-inflammatory and anti-fibrotic activities. TTTE exerts regulatory effects by downregulating key molecules such as Caspase-3, TNF-α, NF-κB and TGF-β. TTTE can be used in the study of liver injury.
    TTTE
  • HY-169784
    PPI-1040
    PPI-1040 is a synthetic PlsEtn, a precursor of plasmalogens. PPI-1040 is an orally available plasmalogen analog that increases plasmalogen in several peripheral tissues of Pex7 low allele mice. PPI-1040 has the potential to replace deficient plasmalogen and inhibit chondrodysplasia punctata (RCDP).
    PPI-1040
  • HY-127030
    Zatosetron
    Zatosetron is an active compound.
    Zatosetron
  • HY-P4671
    Nle-Arg-Phe-NH2 acetate
    Nle-Arg-Phe-NH2 (acetate) is a tripeptide compound, usually in the form of acetate.
    Nle-Arg-Phe-NH2 acetate
  • HY-N0437F
    Progesterone 3-biotin
    Progesterone 3-biotin (Pregn-4-ene-3,20-dione-biotin) is a biotin-labeled probe that allows progesterone to be detected or immobilized using the biotin ligand. Progesterone 3-biotin is the biotinylated derivative of Progesterone (HY-N0437).
    Progesterone 3-biotin
  • HY-114924
    LY465608
    LY465608 is an active compound.
    LY465608
  • HY-129645
    L-647318
    L-647318 is an active compound.
    L-647318
  • HY-W423643
    Benzedrone
    Benzedrone is a synthetic cathinone derivative. Benzedrone can increase the levels of neurotransmitters such as dopamine, serotonin and norepinephrine in the brain, thus producing a stimulant effect. Benzedrone can be used in the research of new psychoactive substances (NPS).
    Benzedrone
  • HY-119508
    Propaphos
    Propaphos is an active compound.
    Propaphos
  • HY-114912
    Benzoadenosine
    Benzoadenosine is an active compound.
    Benzoadenosine
  • HY-114542
    LY 201409
    LY 201409 is an anticonvulsant compound that is an analog of LY-201116 (HY-114705) with improved metabolic activity. LY 201409 antagonizes maximal electroconvulsive-induced seizures, has mixed effects on seizures induced by multiple chemoconvulsants, and affects behavior and sleep in mice.
    LY 201409
  • HY-161648
    Anticancer agent 222
    Anticancer agent 222 (Compound 19) is an orally active anticancer agent that exhibits significant anticancer activity against Huh7, FOCUS, SNU475, SNU182, HepG2, and Hep3B cells (IC50 = 2.9–9.3 μM).
    Anticancer agent 222
  • HY-15189
    17-Aminogeldanamycin
    17-Aminogeldanamycin is an active compound.
    17-Aminogeldanamycin
  • HY-107714
    MNI-D-aspartate
    MNI-D-aspartate is an active compound.
    MNI-D-aspartate
  • HY-12690
    DOTA derivative
    DOTA derivative is a cyclic tosamide benzylic derivative.
    DOTA derivative
  • HY-W009004
    Trilysine
    Trilysine is sourced from L-lysine .
    Trilysine
  • HY-19040
    Ro 16-8714
    Ro 16-8714 is an active compound.
    Ro 16-8714
  • HY-148154
    Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6
    Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6 (n=450) is an active compound. Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6 is a small molecule moiety for pegylation modification in Avacincaptad pegol (HY-147080).
    Poly(oxy-1,2-ethanediyl)-propoxy-amide-C6