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  3. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1342):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W674261
    WAY-620521
    WAY-620521 is an active molecule.
    WAY-620521
  • HY-119012
    L 681217
    L 681217 is an active compound.
    L 681217
  • HY-122040
    5-Chloro hydrochlorothiazide
    5-Chloro hydrochlorothiazide is a derivative of hydrochlorothiazide (HY-B0252), and has diuretic action.
    5-Chloro hydrochlorothiazide
  • HY-118854
    Fepradinol
    Fepradinol is an active compound.
    Fepradinol
  • HY-W747567
    Leukotriene E4 methyl ester
    Leukotriene E4 methyl ester is a methyl ester of Leukotriene E4 (HY-113465). Leukotriene E4 methyl ester can be used for the research of inflammatory diseases.
    Leukotriene E4 methyl ester
  • HY-114968
    p38 MAPK-IN-5
    p38 MAPK-IN-5 is an active compound.
    p38 MAPK-IN-5
  • HY-121247
    Bromotetrandrine
    Bromotetrandrine is a potent inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). Bromotetrandrine shows significant MDR reversal activity in vitro and in vivo, which may be related to the inhibition of P-gp overexpression and the increase in intracellular accumulation of anticancer agents. Bromotetrandrine is a brominated derivative of tetrandrine, which is promising for MDR modulator for tumor assessment.
    Bromotetrandrine
  • HY-125054
    Kelletinin A
    Kelletinin A is an active compound.
    Kelletinin A
  • HY-118608
    2α-Methyl androsterone
    2α-Methyl androsterone is an anabolic androgenic steroid metabolite of mesterolone and drostanolone.
    2α-Methyl androsterone
  • HY-129406
    AF 698
    AF 698 is a phthalate derivative of Apovincamine (HY-135743) that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice.
    AF 698
  • HY-P4454
    Goserelin EP Impurity E
    Goserelin EP Impurity E is the impurity of Goserelin (HY-13673).
    Goserelin EP Impurity E
  • HY-123253
    cis-LY393053
    cis-LY393053 is an active compound.
    cis-LY393053
  • HY-133627
    1,3-Dibromo-1,3-dichloroacetone
    1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant.
    1,3-Dibromo-1,3-dichloroacetone
  • HY-139248
    Paclitaxel octadecanedioate
    Paclitaxel octadecanedioate (compound PTX-FA18) is comprised of Paclitaxel (HY-B0015) conjugated to 1,18-octadecanedioic acid (HY-W005178). Paclitaxel octadecanedioate mixed with human serum albumin (HAS) is cytotoxic to HT-1080, PANC-1, HT-29 and Hela cells (IC50s = 12, 2.48, 8.62, and 64.42 nM, respectively).
    Paclitaxel octadecanedioate
  • HY-N7685
    Podophyllol
    Podophyllol, a derivative of podophyllotoxin esters, has antitumor activity.
    Podophyllol
  • HY-W035404
    1-(1,3-Diphenylpropan-2-yl)pyrrolidine hydrochloride
    1-(1,3-Diphenylpropan-2-yl)pyrrolidine hydrochloride is structurally similar to known dissociative anesthetics.
    1-(1,3-Diphenylpropan-2-yl)pyrrolidine hydrochloride
  • HY-101680
    Zolasartan
    Zolasartan is an active compound.
    Zolasartan
  • HY-113704
    BKM1740
    BKM1740 is an active compound.
    BKM1740
  • HY-W004288R
    Methyl myristate (Standard)
    Methyl myristate (Standard) is the analytical standard of Methyl myristate. This product is intended for research and analytical applications. Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma.
    Methyl myristate (Standard)
  • HY-W142039
    Z-Nle-OH
    Z-Nle-OH is a leucine derivative.
    Z-Nle-OH