2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1533):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W674603
    WAY-351783
    		98.0%
    WAY-351783 is an active molecule.
    WAY-351783
  • HY-152085
    Anticancer agent 94
    Anticancer agent 94 is a 4-Hydroxycoumarin derivative. Anticancer agent 94 can inhibit invasion and migration of lung cancer cells by modulating expression of epithelial-mesenchymal transition (EMT) effectors.
    Anticancer agent 94
  • HY-B0236A
    6-Aminocaproic acid hydrochloride
    6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders.
    6-Aminocaproic acid hydrochloride
  • HY-171241
    Imolamine
    Imolamine is a potent antiplatelet aggregation agent, is a phenyl aminoxidiazole derivative. Imolamine has the potential for the research of coronary heart disease.
    Imolamine
  • HY-169089
    RP-182-PEG3-K(palmitic acid)
    RP-182-PEG3-K palmitic acid (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid inhibits CD206high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid exhibits antitumor efficacy in mouse B16 melanoma allografts.
    RP-182-PEG3-K(palmitic acid)
  • HY-116732
    GW-678248
    GW-678248 is an active compound.
    GW-678248
  • HY-176243
    15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
    15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivate of 15-Deoxy-Δ-12,14-prostaglandin J2 (HY-108568). 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM.
    15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester
  • HY-116727
    RU 24926
    RU 24926 is an active compound.
    RU 24926
  • HY-158927
    5-Chloro-2-thiothinone hydrochloride
    5-Chloro-2-thiothinone (5-Chloro bk-MPA) hydrochloride is structurally similar to known stimulants.
    5-Chloro-2-thiothinone hydrochloride
  • HY-W708886
    Methyl-d3 tetradecanoate
    Methyl-d3 tetradecanoate is the deuterium labeled Methyl myristate (HY-W004288). Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma.
    Methyl-d<sub>3</sub> tetradecanoate
  • HY-118710
    α-Isopropylaminopentiophenone hydrochloride
    		99.98%
    α-Isopropylaminopentiophenone hydrochloride is a α-aminoketone derivative.
    α-Isopropylaminopentiophenone hydrochloride
  • HY-122366
    L-Chlorozotocin
    L-Chlorozotocin is an active compound.
    L-Chlorozotocin
  • HY-P3627
    Nagrestipen
    Nagrestipen, a human macrophage inflammatory protein-1 alpha (MIP-1α) variant, also known as ECI 301. Nagrestipen has antitumor activity and can be used in therapeutic trials to study cancer, tumors, metastases, radiation oncology, and tumor metastasis.
    Nagrestipen
  • HY-125347
    TA-993
    TA-993 is a compound that increases limb blood flow. Its effect of increasing limb blood flow is mediated through the sympathetic nervous system, but not through adrenergic receptors, and its mechanism of action on heart rate may be different.
    TA-993
  • HY-120205
    A-119637
    A-119637 is an active compound.
    A-119637
  • HY-122299
    Motretinide
    Motretinide (Ro 11-1430) is an aromatic retinoic acid with teratogenic activity. Motretinide can be used in studies on medication guidance during pregnancy.
    Motretinide
  • HY-136747
    Nek2/Hec1-IN-1
    N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide is a derivative of INH1 with anticancer activity. It is cytotoxic to MDA-MB-231, MDA-MB-488, HeLa, and K562 cells (IC50s=1.1, 3.4, 1.6, and 1.2 μM, respectively).
    Nek2/Hec1-IN-1
  • HY-172532
    Acetylagmatine acetate
    Acetylagmatine (N-Acetylagmatine) acetate is a product formed by agmatine N-acetyltransferase (AgmNAT) catalyzing the reaction of acetyl-CoA and Agmatine (HY-101238). Agmatine is the product of arginine decarboxylation. Agmatine is a neurotransmitter and neuromodulator in mammalian brain.
    Acetylagmatine acetate
  • HY-A0220
    Rescinnamine
    Rescinnamine is a derivative of the indole alkaloid reserpine. Rescinnamine shows sedative effects. Rescinnamine can be used for hypertension research.
    Rescinnamine
  • HY-W753724
    N-Ethyl 2C-B hydrochloride
    N-Ethyl 2C-B hydrochloride is a phenethylamine with psychoactive properties.
    N-Ethyl 2C-B hydrochloride