2. Signaling Pathways
  3. Immunology/Inflammation
  4. CX3CR1
  5. CX3CR1 Antagonist

CX3CR1 Antagonist

CX3CR1 Antagonists (2):

Cat. No. Product Name Effect Purity
  • HY-175746
    AZD0233
    		Antagonist
    AZD0233 is an orally active CX3CR1 antagonist. AZD0233 modulates the CX3CR1/CX3CL1 signaling axis via immunomodulatory effects. AZD0233 has improved physicochemical properties, metabolic stability, low toxicity and CYP inhibition. AZD0233 improves cardiac function and reduces macrophages and fibrotic scar in mice model of dilated cardiomyopathy. AZD0233 can be used for cardiovascular diseases like dilated cardiomyopathy research.
  • HY-168975
    Fosrugocrixan
    		Antagonist
    Fosrugocrixan is an antagonist for CX3C chemokine receptor 1 (CX3CR1) that exhibits anti-inflammatory activity.