2. Signaling Pathways
  3. Cytoskeleton
  4. Connexin
  5. Connexin Inhibitor

Connexin Inhibitor

Connexin Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-149318
    VRT-534
    		Inhibitor 98.32%
    VRT-534 (Compound 3) is a chemical chaperone targeting connexin 26 (Cx26). Vrt-534 exhibits dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively. Vrt-534 can be used in research related to hearing impairment.
  • HY-149318B
    (R,R)-VRT-534
    		Inhibitor
    (R,R)-VRT-534 is the (R,R)-enantiomer of VRT-534 (HY-149318). VRT-534 (Compound 3) is a chemical chaperone targeting connexin 26 (Cx26). Vrt-534 exhibits dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively. Vrt-534 can be used in research related to hearing impairment.