2. Signaling Pathways
  3. Others
  4. Biochemical Assay Reagents
  5. Biochemical Assay Reagents Ligand

Biochemical Assay Reagents Ligand

Biochemical Assay Reagents Ligand (1):

Cat. No. Product Name Effect Purity
  • HY-Q51222
    ZINC110492
    		Ligand
    ZINC110492 is a selective ligand of CS-ΔEx4 (a splicing isoform of citrate synthase (CS)). ZINC110492 does not bind to CS full-length (CS-FL). ZINC110492 inhibits colorectal cancer (CRC) cell growth in cells overexpressing CS-ΔEx4 with an IC50 of 7.840 µM. ZINC110492 significantly decreases both citrate and 2-hydroxyglutarate (2-HG) levels in the CS-ΔEx4-overexpressing SW1116 cells.