2. Signaling Pathways
  3. Immunology/Inflammation
  4. BCL6
  5. BCL6 Inducer

BCL6 Inducer

BCL6 Inducer (1):

Cat. No. Product Name Effect Purity
  • HY-173364
    EB-TCIP
    		Inducer
    EB-TCIP (BAK-04-212) is a bivalent molecule comprised of AP1867 (HY-114434) and BI-3812 (HY-111381). EB-TCIP can form a reversible ternary complex between FKBPF36V and BCL6BTB. EB-TCIP recruits FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, leading to rapid expression of BCL6 target genes (eg: SOCS2 and CXCL11). EWS/FLI1 is a fusion transcription factors in Ewing sarcoma. EB-TCIP can be used for research of deregulated transcription in cancer.