2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Apolipoprotein

Apolipoprotein

Plasma lipoprotein metabolism is regulated and controlled by the specific apolipoprotein (apo-) constituents of the various lipoprotein classes. The major apolipoproteins include apoE, apoB, apoA-I, apoA-II, apoA-IV, apoC-I, apoC-II, and apoC-III. Specific apolipoproteins function in the regulation of lipoprotein metabolism through their involvement in the transport and redistribution of lipids among various cells and tissues, through their role as cofactors for enzymes of lipid metabolism, or through their maintenance of the structure of the lipoprotein particles.

Apolipoprotein Isoform Specific Products:

Apolipoprotein Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-RS00845
    APOC2 Human Pre-designed siRNA Set A

    APOC2 Human Pre-designed siRNA Set A contains three designed siRNAs for APOC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Components

    APOC2 siRNA-1: 5 nmol (HPLC)

    APOC2 siRNA-2: 5 nmol (HPLC)

    APOC2 siRNA-3: 5 nmol (HPLC)

    siRNA Negative Control: 5 nmol (HPLC)

    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

    GAPDH siRNA Positive Control: 5 nmol (HPLC)
    APOC2 Human Pre-designed siRNA Set A
  • HY-173323
    Lp(a)-IN-7
    		Inhibitor
    Lp(a)-IN-7 (example 1) is a lipoprotein (a) (Lp(a)) formation inhibitor with an IC50 of 2.51 nM in conditioned media containing apolipoprotein B (apoB) and apolipoprotein(a). Lp(a)-IN-7 can be used for the study of cardiovascular disease.
    Lp(a)-IN-7
  • HY-P10188
    apoB (4372-4392)
    		Inhibitor
    apoB (4372-4392) is a potent lipoprotein(a) assembly inhibitor, with an IC50 of 40 μM. apoB (4372-4392) can noncovalently bind to apolipoprotein(a) with high affinity.
    apoB (4372-4392)
  • HY-111346R
    1-Linoleoyl Glycerol (Standard)
    1-Linoleoyl Glycerol (Standard) is the analytical standard of 1-Linoleoyl Glycerol. This product is intended for research and analytical applications. 1-Linoleoyl glycerol is a LpPLA2 inhibitor. 1-Linoleoyl glycerol acts as a precursor for synthesizing various functional lipids, such as phospholipids. 1-Linoleoyl glycerol mitigates inflammation induced by Apolipoprotein CIII (reduction of IL-6).
    1-Linoleoyl Glycerol (Standard)
  • HY-RS19408
    Apoa4 Mouse Pre-designed siRNA Set A

    Apoa4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Components

    Apoa4 siRNA-1: 5 nmol (HPLC)

    Apoa4 siRNA-2: 5 nmol (HPLC)

    Apoa4 siRNA-3: 5 nmol (HPLC)

    siRNA Negative Control: 5 nmol (HPLC)

    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

    GAPDH siRNA Positive Control: 5 nmol (HPLC)
    Apoa4 Mouse Pre-designed siRNA Set A
  • HY-RS19983
    Apoa2 Mouse Pre-designed siRNA Set A

    Apoa2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Apoa2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Components

    Apoa2 siRNA-1: 5 nmol (HPLC)

    Apoa2 siRNA-2: 5 nmol (HPLC)

    Apoa2 siRNA-3: 5 nmol (HPLC)

    siRNA Negative Control: 5 nmol (HPLC)

    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

    GAPDH siRNA Positive Control: 5 nmol (HPLC)
    Apoa2 Mouse Pre-designed siRNA Set A
  • HY-171464A
    Lp(a)-IN-5 hydrochloride
    		Inhibitor
    Lp(a)-IN-5 (Compound A) hydrochloride is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 hydrochloride inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 hydrochloride is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases.
    Lp(a)-IN-5 hydrochloride
Apolipoprotein Isoform Comparison

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