Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W017617

Fmoc-Ser(HPO3Bzl)-OH		99.73%
Fmoc-Ser(HPO3Bzl)-OH is a serine derivative.

HY-W006886

Fmoc-(R)-2-(7-octenyl)Ala-OH		98.85%
Fmoc-(R)-2-(7-octenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize inhibitor peptides that combinatorially inactivate ErbB1, ErbB2, and ErbB3.

HY-W008986

Fmoc-Lys(Ac)-OH		99.79%
Fmoc-Lys(Ac)-OH is a lysine derivative.

HY-W018865

Methyl D-cysteinate hydrochloride		≥98.0%
Methyl D-cysteinate hydrochloride is a cysteine derivative.

HY-W013998

Glycyl-L-phenylalanine		99.74%
Glycyl-L-phenylalanine is a phenylalanine derivative.

HY-59260

N-Boc-L-tert-Leucine		≥98.0%
N-Boc-L-tert-Leucine is a leucine derivative.

HY-101552B

L,L-Dityrosine hydrochloride		99.91%
L,L-Dityrosine hydrochloride (o,o'-Dityrosine hydrochloride) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin.

HY-W014663

(S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoic acid		99.93%
(S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoic acid is a serine derivative.

HY-W041867

Boc-Ser-OtBu		≥98.0%
Boc-Ser-OtBu is a serine derivative.

HY-79106

L-Biphenylalanine		99.95%
L-Biphenylalanine is a phenylalanine derivative.

HY-W141949

L-Glutamic acid potassium salt monohydrate		≥98.0%
L-Glutamic acid potassium salt monohydrate is a glutamic acid derivative.

HY-B1732

DL-3-Phenylalanine		99.99%
DL-3-Phenylalanine is a phenylalanine derivative.

HY-59140

(S)-2-Amino-3,3-dimethylbutanoic acid		≥98.0%
(S)-2-amino-3,3-dimethylbutanoic acid is a leucine derivative.

HY-W041982

Fmoc-Asp-OMe		99.29%
Fmoc-Asp-OMe is an aspartic acid derivative.

HY-W010782

Fmoc-Lys(Z)-OH		99.53%
Fmoc-Lys(Z)-OH is a lysine derivative.

HY-Y0749

Glutamic acid dimethyl ester hydrochloride
Glutamic acid dimethyl ester hydrochloride is a glutamic acid derivative.

HY-W013750

Fmoc-Arg-OH		99.95%
Fmoc-Arg-OH (Fmoc-L-Arginine), an Fmoc modified Arginine, is used in peptide synthesis.

HY-W011156

Mpa(Trt)		99.77%
Mpa(Trt) is a 3-mercaptopropionic acid derivative containing a trityl protecting group (Trt) and can be used to synthesize compounds with anti-leukemia activity.

HY-W007722

H-Ala-OtBu.HCl		≥98.0%
H-Ala-OtBu.HCl is an alanine derivative.

HY-W001158S

N,N-Dimethylglycine-d₆ hydrochloride		99.46%
N,N-Dimethylglycine-d₆ (Dimethylglycine-d₆) hydrochloride is the deuterium labeled N,N-Dimethylglycine hydrochloride (HY-W001158). N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects.

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