Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1536):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-32688

Boc-Ser-OMe		99.11%
Boc-Ser-OMe is a serine derivative.

HY-W008029

H-Lys(Z)-OtBu.HCl		99.93%
H-Lys(Z)-OtBu.HCl is a lysine derivative.

HY-112716

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride		≥99.0%
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK), a trypsin like protease inhibitor, sensitizes HeLa cells to Fas-mediated cell death.

HY-W041867

Boc-Ser-OtBu		≥98.0%
Boc-Ser-OtBu is a serine derivative.

HY-79106

L-Biphenylalanine		99.95%
L-Biphenylalanine is a phenylalanine derivative.

HY-W008558

Fmoc-N-Me-Leu-OH		99.23%
Fmoc-N-Me-Leu-OH, an N-Fmoc-N-methyl amino acid, is available for the peptide-coupling reaction.

HY-W013726

Fmoc-Phe(4-Br)-OH		99.83%
Fmoc-Phe(4-Br)-OH is a phenylalanine derivative that can be used for compound synthesis.

HY-W010782

Fmoc-Lys(Z)-OH		99.53%
Fmoc-Lys(Z)-OH is a lysine derivative.

HY-W019676

Boc-Tyr-OtBu		99.68%
Boc-Tyr-OtBu is a tyrosine derivative.

HY-W008021

Fmoc-D-Leu-OH		99.93%
Fmoc-D-Leu-OH is a leucine derivative.

HY-W008694

N-Benzoyl-L-arginine ethyl ester hydrochloride		98.18%
N-Benzoyl-L-arginine ethyl ester hydrochloride is an arginine derivative.

HY-W013714

Fmoc-Phe(4-I)-OH		99.63%
Fmoc-Phe(4-I)-OH is a phenylalanine derivative.

HY-W048207

N6-Propionyl-L-lysine		99.86%
N6-Propionyl-L-lysine is a lysine derivative.

HY-W006886

Fmoc-(R)-2-(7-octenyl)Ala-OH		98.85%
Fmoc-(R)-2-(7-octenyl)Ala-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize inhibitor peptides that combinatorially inactivate ErbB1, ErbB2, and ErbB3.

HY-W008986

Fmoc-Lys(Ac)-OH		99.79%
Fmoc-Lys(Ac)-OH is a lysine derivative.

HY-W013998

Glycyl-L-phenylalanine		99.74%
Glycyl-L-phenylalanine is a phenylalanine derivative.

HY-W141821

Fmoc-Phe(CF2PO3)-OH		≥98.0%
Fmoc-Phe(CF2PO3)-OH is a phenylalanine derivative.

HY-W141858

N-(3-Indolylacetyl)-L-alanine		99.91%
N-(3-Indolylacetyl)-L-alanine (Indoleacetylalanine) is an indoleacetylamino acid. N-(3-Indolylacetyl)-L-alanine appears to increase callus growth and reduces the ability of growths to differentiate into shoots of Phalaenopsis orchids.

HY-W041989

Fmoc-Oic-OH		99.72%
Fmoc-Oic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg¹⁰]HOE 140, which has bradykinin B1 antagonist activity.

HY-W041982

Fmoc-Asp-OMe		99.29%
Fmoc-Asp-OMe is an aspartic acid derivative.

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