Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1608):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W008560

Fmoc-Gly(allyl)-OH		99.94%
Fmoc-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative.

HY-W259767

3-Iodo-L-phenylalanine		99.29%
3-Iodo-L-phenylalanine is an unnatural amino acid that can be used for partial codon redistribution. 3-Iodo-L-phenylalanine has a high efficiency in Ser AGU codon reassignment, and also has a certain effect in Ser UCG codon reassignment. 3-Iodo-L-phenylalanine can be used in the study of genetic code expansion and protein engineering.

HY-79106

L-Biphenylalanine		99.95%
L-Biphenylalanine is a phenylalanine derivative.

HY-W141858

N-(3-Indolylacetyl)-L-alanine		99.91%
N-(3-Indolylacetyl)-L-alanine (Indoleacetylalanine) is an indoleacetylamino acid. N-(3-Indolylacetyl)-L-alanine appears to increase callus growth and reduces the ability of growths to differentiate into shoots of Phalaenopsis orchids.

HY-W008558

Fmoc-N-Me-Leu-OH		99.36%
Fmoc-N-Me-Leu-OH, an N-Fmoc-N-methyl amino acid, is available for the peptide-coupling reaction.

HY-W013190

Fmoc-HoPro-OH		99.96%
Fmoc-HoPro-OH is a proline derivative.

HY-W141919

N-(2-Methylbutyryl)glycine		99.0%
N-(2-Methylbutyryl)glycine is a Glycine (HY-Y0966) derivative.

HY-W011156

Mpa(Trt)		99.77%
Mpa(Trt) is a 3-mercaptopropionic acid derivative containing a trityl protecting group (Trt) and can be used to synthesize compounds with anti-leukemia activity.

HY-B0393

Fudosteine		98.0%
Fudosteine is a cysteine derivative and a mucoactive agent. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression.

HY-W009003

Fmoc-Tyr-OH		99.82%
Fmoc-Tyr-OH is a tyrosine derivative.

HY-W002074

D-Cysteine hydrochloride		98.0%
D-Cysteine hydrochloride is a cysteine derivative.

HY-W013962

4-(Trifluoromethyl)-L-phenylalanine		99.89%
4-(Trifluoromethyl)-L-phenylalanine is a phenylalanine derivative.

HY-W007655

Fmoc-D-Lys(Boc)-OH		99.87%
Fmoc-D-Lys (Boc)-OH is a protected D-lysine derivative with an Fmoc group protecting the amino group and a Boc group protecting the side chain. Fmoc-D-Lys (Boc)-OH ensures the accurate integration of D-lysine into the peptide chain, maintaining the peptide's specific conformation and biological activity. Fmoc-D-Lys (Boc)-OH can be used in the synthesis of peptides containing unnatural amino acids.

HY-W008986

Fmoc-Lys(Ac)-OH		99.79%
Fmoc-Lys(Ac)-OH is a lysine derivative.

HY-W011830

H-Phe-OtBu.HCl		99.44%
H-Phe-OtBu.HCl is a phenylalanine derivative.

HY-W010838

Fmoc-D-Bip(4,4’)-OH		99.57%
Fmoc-D-Bip(4,4’)-OH is an alanine derivative.

HY-W011342

Fmoc-Sar-OH		99.93%
Fmoc-Sar-OH is a Glycine (HY-Y0966) derivative.

HY-W014663

(S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoic acid		99.93%
(S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoic acid is a serine derivative.

HY-W141949

L-Glutamic acid potassium salt monohydrate		98.0%
L-Glutamic acid potassium salt monohydrate is a glutamic acid derivative.

HY-W041982

Fmoc-Asp-OMe		99.29%
Fmoc-Asp-OMe is an aspartic acid derivative.

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