Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W141919

N-(2-Methylbutyryl)glycine		99.0%
N-(2-Methylbutyryl)glycine is a Glycine (HY-Y0966) derivative.

HY-W019676

Boc-Tyr-OtBu		99.68%
Boc-Tyr-OtBu is a tyrosine derivative.

HY-22062

Fmoc-Chg-OH		99.98%
Fmoc-Chg-OH is a Glycine (HY-Y0966) derivative.

HY-20561A

N-Methyl-D-valine		≥98.0%
N-Methyl-D-valine is a valine derivative.

HY-79132

N-Fmoc-O-benzyl-L-tyrosine		99.15%
N-Fmoc-O-benzyl-L-tyrosine is a tyrosine derivative.

HY-W007655

Fmoc-D-Lys(Boc)-OH		99.87%
Fmoc-D-Lys (Boc)-OH is a protected D-lysine derivative with an Fmoc group protecting the amino group and a Boc group protecting the side chain. Fmoc-D-Lys (Boc)-OH ensures the accurate integration of D-lysine into the peptide chain, maintaining the peptide's specific conformation and biological activity. Fmoc-D-Lys (Boc)-OH can be used in the synthesis of peptides containing unnatural amino acids.

HY-78927

N-Boc-L-Prolinal		98.81%
N-Boc-L-Prolinal is a proline with a Boc protecting group, which can be used to synthesize biologically active peptide mimetics, such as the synthesis of Dolastatin 10 (HY-15580) analogs with anti-colon cancer activity.

HY-W018386

3-Bromo-L-tyrosine		98.74%
3-Bromo-L-tyrosine (3-Bromo-Tyr) is a tyrosine derivative.

HY-W013190

Fmoc-HoPro-OH		99.96%
Fmoc-HoPro-OH is a proline derivative.

HY-B0393

Fudosteine		≥98.0%
Fudosteine is a cysteine derivative and a mucoactive agent. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression.

HY-40114

Boc-L-proline		99.79%
Boc-L-proline is an amino acid derivative. As an important intermediate in organic synthesis, Boc-L-proline can be used for peptide synthesis.

HY-W009003

Fmoc-Tyr-OH		99.82%
Fmoc-Tyr-OH is a tyrosine derivative.

HY-W019032

Fmoc-D-Dab(Boc)-OH		98.81%
Fmoc-D-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with antibacterial activity.

HY-W013962

4-(Trifluoromethyl)-L-phenylalanine		99.89%
4-(Trifluoromethyl)-L-phenylalanine is a phenylalanine derivative.

HY-W013714

Fmoc-Phe(4-I)-OH		99.63%
Fmoc-Phe(4-I)-OH is a phenylalanine derivative.

HY-W007578

H-β-Ala-OtBu.HCl		98.13%
H-β-Ala-OtBu.HCl is an alanine derivative.

HY-41650

Boc-Ala-NMe(OMe)
Boc-Ala-NMe(OMe) is an alanine derivative.

HY-W097491

L-Methionine sulfone		99.95%
L-Methionine sulfone is a sulfonic acid derivative of L-Methionine (HY-N0326). L-Methionine in the presence of a number of oxidizing systems is readily converted to L-Methionine sulfone.

HY-W039756

Boc-Ala-Ala-OH		99.04%
Boc-Ala-Ala-OH (NSC 334362) is an Alanine derivative. Boc-Ala-Ala-OH is used in the preparation of anti-bacterial agent.

HY-W141928

N-Isobutyrylglycine
N-Isobutyrylglycine is a Glycine (HY-Y0966) derivative.

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