Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W041984

Fmoc-Cpg-OH		99.98%
Fmoc-Cpg-OH is a Glycine (HY-Y0966) derivative.

HY-W010962

Fmoc-Dap(Alloc)-OH		99.59%
Fmoc-Dap(Alloc)-OH is an alanine derivative.

HY-W014919

H-Phe(2-Cl)-OH		99.92%
H-Phe(2-Cl)-OH is a phenylalanine derivative.

HY-W008064

Fmoc-Cit-OH		99.32%
Fmoc-Cit-OH (Fmoc-L-Citrulline) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize a degradable ADC linker composed of a valine-citrulline (Val-Cit) motif.

HY-W008696

Fmoc-Thr-OH		99.37%
Fmoc-Thr-OH is a threonine derivative.

HY-W008024

Fmoc-Dab(Boc)-OH		99.56%
Fmoc-Dab(Boc)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize somatostatin analogs that inhibit neointima formation induced by balloon injury in rats without altering growth hormone release.

HY-W040804

2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride		99.51%
2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrochloride is an alanine derivative.

HY-W011026

Fmoc-D-Phe-OH		99.90%
Fmoc-D-Phe-OH is a phenylalanine derivative.

HY-W008075

Fmoc-Asp(OAll)-OH		99.89%
Fmoc-Asp(OAll)-OH is an aspartic acid derivative.

HY-W008642

Leu-Leu-OH		98.75%
Leu-Leu-OH (L-Leucyl-L-leucine), a Leu derivative, is a neutral dipeptide that can be used to study the functionality of dileucine motifs.

HY-139666

N-Palmitoyl-L-glutamine		99.88%
N-Palmitoyl-L-glutamine is a Glutamine derivative.

HY-W048911

(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine		99.73%
(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine is a histidine derivative.

HY-112716

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride		≥99.0%
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK), a trypsin like protease inhibitor, sensitizes HeLa cells to Fas-mediated cell death.

HY-W007618

Boc-Lys-OH		99.56%
Boc-Lys-OH is an amino acid derivative. Boc-Lys-OH plays a key role in peptide synthesis and redox activity research.

HY-W008113

Boc-L-Homoserine
Boc-L-Homoserine is a serine derivative.

HY-W013726

Fmoc-Phe(4-Br)-OH		99.83%
Fmoc-Phe(4-Br)-OH is a phenylalanine derivative that can be used for compound synthesis.

HY-W014375

Arginine hydrochloride		≥98.0%
Arginine hydrochloride is an arginine derivative.

HY-W048739

Fmoc-α-Me-Leu-OH		99.50%
Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity.

HY-W048918

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-homocysteine		99.78%
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-homocysteine is a cysteine derivative.

HY-W008446

(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid		99.80%
(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid is a proline derivative.

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