Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1536):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W010893

Fmoc-2-Nal-OH		99.59%
Fmoc-2-Nal-OH is an alanine derivative.

HY-113119

N-Butyrylglycine		98.26%
N-Butyrylglycine is a Glycine (HY-Y0966) derivative.

HY-66024

Fmoc-Lys(Boc,Me)-OH		99.94%
Fmoc-Lys(Boc,Me)-OH is a lysine derivative.

HY-W039102

N-Fmoc-N,O-dimethyl-L-serine		98.25%
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells.

HY-W008446

(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid		99.80%
(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid is a proline derivative.

HY-75331

Glycine tert-butyl ester hydrochloride		≥98.0%
Glycine tert-butyl ester hydrochloride is a Glycine (HY-Y0966) derivative.

HY-139666

N-Palmitoyl-L-glutamine		99.88%
N-Palmitoyl-L-glutamine is a Glutamine derivative.

HY-Y0978

Boc-Glycine		99.81%
Boc-Glycine is a Glycine (HY-Y0966) derivative.

HY-W011135

Fmoc-D-Isoleucine		99.99%
Fmoc-D-Isoleucine is an isoleucine derivative.

HY-W008072

Fmoc-D-Ala-OH		99.52%
Fmoc-D-Ala-OH is an alanine derivative.

HY-W008371

Fmoc-Met-OH		99.50%
Fmoc-Met-OH is a Methionine (HY-13694) derivative.

HY-W008688

Fmoc-L-Norleucine		99.58%
Fmoc-L-Norleucine is a leucine derivative.

HY-W048918

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-homocysteine		99.78%
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-trityl-L-homocysteine is a cysteine derivative.

HY-P1851A

AGA-(C8R) HNG17, humanin derivative TFA		98.34%
AGA-(C8R) HNG17, humanin derivative TFA is a potent humanin (HN) derivative. AGA-(C8R) HNG17, humanin derivative completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.

HY-W097054

Fmoc-L-cysteic acid
Fmoc-L-cysteic acid is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize triarylsulfonium compounds for radiolabeling of peptides.

HY-W008156

Fmoc-D-Ser(tBu)-OH		99.93%
Fmoc-D-Ser(tBu)-OH is a serine derivative.

HY-W009088

Fmoc-Tle-OH		99.76%
Fmoc-Tle-OH is a leucine derivative.

HY-W018386

3-Bromo-L-tyrosine		98.74%
3-Bromo-L-tyrosine (3-Bromo-Tyr) is a tyrosine derivative.

HY-W011026

Fmoc-D-Phe-OH		99.90%
Fmoc-D-Phe-OH is a phenylalanine derivative.

HY-W048911

(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine		99.73%
(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine is a histidine derivative.

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