Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-79676

Methyl (R)-2-((tert-butoxycarbonyl)amino)-3-iodopropanoate		99.96%
Methyl (R)-2-((tert-butoxycarbonyl)amino)-3-iodopropanoate is an alanine derivative.

HY-W010893

Fmoc-2-Nal-OH		99.59%
Fmoc-2-Nal-OH is an alanine derivative.

HY-113119

N-Butyrylglycine		99.93%
N-Butyrylglycine is a Glycine (HY-Y0966) derivative.

HY-22297

Fmoc-Ser-OtBu		99.84%
Fmoc-Ser-OtBu is a serine derivative.

HY-101404A

L-Homocysteine thiolactone hydrochloride		99.99%
L-Homocysteine thiolactone hydrochloride is an intramolecular thioester of Homocysteine. Homocysteine thiolactone hydrochloride prevents translational incorporation of homocysteine into proteins. L-Homocysteine thiolactone hydrochloride can induce elevated HHcy (hyperhomocysteinemia) in mice.

HY-W008156

Fmoc-D-Ser(tBu)-OH		99.93%
Fmoc-D-Ser(tBu)-OH is a serine derivative.

HY-W048688

Fmoc-Trp(Me)-OH		99.66%
Fmoc-Trp (Me)-OH is an amino acid derivative. Fmoc-Trp (Me)-OH is a compound formed by introducing a methyl group into the nitrogen atom (N-1 position) of the indole ring of tryptophan (Trp) and protecting the amino group with an Fmoc (9-fluorenylmethoxycarbonyl) group. Fmoc-Trp (Me)-OH can be used for protein or peptide synthesis.

HY-W036333

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-N2-methyl-L-lysine		99.75%
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-N2-methyl-L-lysine is a lysine derivative.

HY-W048693

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-L-serine		98.54%
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-L-serine is a serine derivative.

HY-Z0424

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester		99.42%
(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester is an alanine derivative.

HY-W006064

(S)-2-Aminopent-4-ynoic acid		99.91%
(S)-2-Aminopent-4-ynoic acid is a synthetic amino acid. (S)-2-Aminopent-4-ynoic acid can be used in synthesis of folate-conjugates and corresponding metal-chelate complexes. (S)-2-Aminopent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W002300

Boc-L-Valine		98.44%
Boc-L-Valine is a valine derivative.

HY-128676

N-ε-propargyloxycarbonyl-L-lysine hydrochloride		99.80%
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals. N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133803

Z-Ala-Ala-OH		99.84%
Z-Ala-Ala-OH is a non-polar amino acid that can be used in enzymatic peptide synthesis.

HY-W010959

Fmoc-Asp-OtBu		99.91%
Fmoc-Asp-OtBu is an aspartic acid derivative.

HY-W008426

Fmoc-D-Tyr(tBu)-OH		99.91%
Fmoc-D-Tyr(tBu)-OH is a tyrosine derivative.

HY-20561

N-Methyl-L-valine		≥98.0%
N-Methyl-L-valine is a valine derivative.

HY-Y0978

Boc-Glycine		99.81%
Boc-Glycine is a Glycine (HY-Y0966) derivative.

HY-W010895

Fmoc-1-Nal-OH		99.89%
Fmoc-1-Nal-OH is an alanine derivative.

HY-P2237

Boc-Leu-Gly-Arg-AMC		98.61%
Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays.

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