Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W009592

Glycyl-L-tyrosine		99.59%
Glycyl-L-tyrosine is a synthetic dipeptide that can be used as a food additive for tyrosine supplementation.

HY-W000438

N-Boc-O-tosyl hydroxylamine		99.55%
N-Boc-O-tosyl hydroxylamine is used as a safe and efficient nitrogen source for the N-amination of aryl and alkyl amines.

HY-W010943

Fmoc-Tyr(Me)-OH		99.91%
Fmoc-Tyr(Me)-OH is a tyrosine derivative.

HY-W009088

Fmoc-Tle-OH		99.76%
Fmoc-Tle-OH is a leucine derivative.

HY-W010732

Fmoc-L-Lys(ivDde)-OH		99.87%
Fmoc-L-Lys(ivDde)-OH is a lysine derivative.

HY-W011020

Fmoc-3-Pal-OH		99.98%
Fmoc-3-Pal-OH is an alanine derivative.

HY-W008371

Fmoc-Met-OH		99.86%
Fmoc-Met-OH is a Methionine (HY-13694) derivative.

HY-W008688

Fmoc-L-Norleucine		99.58%
Fmoc-L-Norleucine is a leucine derivative.

HY-W010721

Fmoc-Lys(Biotin)-OH		98.04%
Fmoc-Lys(Biotin)-OH is a lysine derivative.

HY-W039102

N-Fmoc-N,O-dimethyl-L-serine		98.25%
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells.

HY-75331

Glycine tert-butyl ester hydrochloride		≥98.0%
Glycine tert-butyl ester hydrochloride is a Glycine (HY-Y0966) derivative.

HY-W015231

Boc-β-Ala-OH		≥98.0%
Boc-β-Ala-OH is an alanine derivative.

HY-W008072

Fmoc-D-Ala-OH		99.52%
Fmoc-D-Ala-OH is an alanine derivative.

HY-W105804

Selenocystamine dihydrochloride		99.63%
Selenocystamine dihydrochloride is a selenocysteine derivative that can be used in the synthesis of other active compounds. Selenocystamine dihydrochloride can also induce the aggregation of amphiphilic p-sulfonatocalixarene to form supramolecular nanoparticles.

HY-W010276

Gly-Sar		99.56%
Gly-Sar is a Glycine (HY-Y0966) derivative.

HY-W010698

Fmoc-D-Arg(Pbf)-OH		99.98%
Fmoc-D-Arg(Pbf)-OH is an arginine derivative.

HY-W007942

Fmoc-β-Ala-OH		99.93%
Fmoc-β-Ala-OH is an alanine derivative.

HY-W010922

Fmoc-Dap(Boc)-OH		99.98%
Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists.

HY-W008995

Fmoc-Phe(4-F)-OH		99.88%
Fmoc-Phe(4-F)-OH is a phenylalanine derivative.

HY-W041989

Fmoc-Oic-OH		99.86%
Fmoc-Oic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as [desArg¹⁰]HOE 140, which has bradykinin B1 antagonist activity.

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