Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1536):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W010895

Fmoc-1-Nal-OH		99.89%
Fmoc-1-Nal-OH is an alanine derivative.

HY-22297

Fmoc-Ser-OtBu		99.84%
Fmoc-Ser-OtBu is a serine derivative.

HY-W010698

Fmoc-D-Arg(Pbf)-OH		99.98%
Fmoc-D-Arg(Pbf)-OH is an arginine derivative.

HY-W010943

Fmoc-Tyr(Me)-OH		99.91%
Fmoc-Tyr(Me)-OH is a tyrosine derivative.

HY-W010922

Fmoc-Dap(Boc)-OH		99.98%
Fmoc-Dap(Boc)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bicyclic peptide tachykinin NK2 antagonists.

HY-W048693

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-L-serine		98.54%
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-L-serine is a serine derivative.

HY-101552B

L,L-Dityrosine hydrochloride		99.91%
L,L-Dityrosine hydrochloride (o,o'-Dityrosine hydrochloride) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin.

HY-W011020

Fmoc-3-Pal-OH		99.98%
Fmoc-3-Pal-OH is an alanine derivative.

HY-128676

N-ε-propargyloxycarbonyl-L-lysine hydrochloride		98.34%
N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals. N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133803

Z-Ala-Ala-OH		99.84%
Z-Ala-Ala-OH is a non-polar amino acid that can be used in enzymatic peptide synthesis.

HY-W105804

Selenocystamine dihydrochloride		99.63%
Selenocystamine (dihydrochloride) is aselenocysteine derivatives.

HY-W008426

Fmoc-D-Tyr(tBu)-OH		99.91%
Fmoc-D-Tyr(tBu)-OH is a tyrosine derivative.

HY-113119

N-Butyrylglycine		98.26%
N-Butyrylglycine is a Glycine (HY-Y0966) derivative.

HY-20561

N-Methyl-L-valine		≥98.0%
N-Methyl-L-valine is a valine derivative.

HY-W048688

Fmoc-Trp(Me)-OH		99.66%
Fmoc-Trp (Me)-OH is an amino acid derivative. Fmoc-Trp (Me)-OH is a compound formed by introducing a methyl group into the nitrogen atom (N-1 position) of the indole ring of tryptophan (Trp) and protecting the amino group with an Fmoc (9-fluorenylmethoxycarbonyl) group. Fmoc-Trp (Me)-OH can be used for protein or peptide synthesis.

HY-W039102

N-Fmoc-N,O-dimethyl-L-serine		98.25%
N-Fmoc-N,O-dimethyl-L-serine is a serine derivative that can be used for coibamide A synthesis. Coibamide A is a marine natural product with potent antiproliferative activity against human cancer cells.

HY-W015231

Boc-β-Ala-OH		≥98.0%
Boc-β-Ala-OH is an alanine derivative.

HY-Z0424

(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester		99.42%
(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester is an alanine derivative.

HY-W010982

Fmoc-Phe(4-NH2)-OH		98.98%
Fmoc-Phe(4-NH2)-OH is a phenylalanine derivative.

HY-P2237

Boc-Leu-Gly-Arg-AMC		98.61%
Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays.

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