Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1608):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W012487

H-Phe(3-Cl)-OH		98.59%
H-Phe(3-Cl)-OH is a phenylalanine derivative.

HY-79404A

Boc-beta-t-butyl-d-alanine		98.87%
Boc-beta-t-butyl-d-alanine is an intermediate, can be used in the synthesis of peptides and other amino acids.

HY-44070

N-(tert-Butoxycarbonyl)-O-(tert-butyl)-L-threonyl-L-proline
N-(tert-Butoxycarbonyl)-O-(tert-butyl)-L-threonyl-L-proline is a proline derivative.

HY-W002237

2-Amino-2-(4-chlorophenyl)acetic acid		≥98.0%
2-Amino-2-(4-chlorophenyl)acetic acid is a Glycine (HY-Y0966) derivative.

HY-W008297

Z-Thr-OMe		99.33%
Z-Thr-OMe is a threonine derivative.

HY-W013300

Boc-N-Me-Phe-OH		99.70%
Boc-N-Me-Phe-OH is a phenylalanine derivative.

HY-20838B

(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid		≥98.0%
(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid is a Glycine (HY-Y0966) derivative.

HY-W015177

H-Phe(3-CN)-OH		99.75%
H-Phe(3-CN)-OH is a phenylalanine derivative.

HY-W014373

L-Lysine ethyl ester dihydrochloride
L-Lysine ethyl ester dihydrochloride is a lysine derivative.

HY-77635

Z-D-Chg-OH
Z-D-Chg-OH is a glycine derivative that can be used for amino acid synthesis.

HY-W008942

Z-Leu-OH.DCHA		99.85%
Z-Leu-OH.DCHA is a leucine derivative.

HY-W142161

Fmoc-N-Me-His(Trt)-OH		98.24%
Fmoc-N-Me-His(Trt)-OH (Fmoc-MeHis(Trt)-OH) is a is an amino acid derivative containing amino and carboxyl groups. Fmoc-N-Me-His(Trt)-OH for the synthesis of Fmoc-MeHis (Trt) -Leu-OH.

HY-W048828

((Benzyloxy)carbonyl)-L-alanyl-L-valine
((Benzyloxy)carbonyl)-L-alanyl-L-valine is a valine derivative.

HY-W004064

N-Boc-O-Benzyl-D-serine		99.66%
N-Boc-O-Benzyl-D-serine is a serine derivative.

HY-W008182

H-Lys(Z)-OMe.HCl		99.86%
H-Lys(Z)-OMe.HCl is a lysine derivative.

HY-W052493

2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid is a tyrosine derivative.

HY-Y0007

N-[(Benzyloxy)carbonyl]-L-alanine		99.38%
N-[(Benzyloxy)carbonyl]-L-alanine is an alanine derivative.

HY-W142035

N-Benzoyl-L-leucine		99.61%
N-Benzoyl-L-leucine is a leucine derivative.

HY-W009648

O-tert-Butylthreoninetert-butyl ester		99.89%
O-tert-Butylthreoninetert-butyl ester is a threonine derivative.

HY-W015233

H-D-Asp(OtBu)-OH		99.91%
H-D-Asp(OtBu)-OH is an aspartic acid derivative.

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