Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1560):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-Y1844

Fmoc-D-Glu(OtBu)-OH		99.96%
Fmoc-D-Glu(OtBu)-OH is a glutamic acid derivative.

HY-W008872

Fmoc-Lys(Mtt)-OH		99.61%
Fmoc-Lys(Mtt)-OH is a lysine derivative.

HY-W025807

Fmoc-His(Boc)-OH
Fmoc-His(Boc)-OH is a histidine derivative.

HY-W023493

DL-Allylglycine		≥98.0%
DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures.

HY-41121

Boc-L-Ala-OH		≥98.0%
Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein.

HY-W005144

Boc-Lys(Fmoc)-OH		99.62%
Boc-Lys(Fmoc)-OH is a lysine derivative.

HY-W142080

α-Methyl-DL-tryptophan		99.92%
α-Methyl-DL-tryptophan (α-Methyltryptophan), a tryptophan derivative, is a selective SLC6A14 blocker. In estrogen receptor (ER)-positive breast cancer cells, α-Methyl-DL-tryptophan inhibits mTOR and activates autophagy and apoptosis. α-Methyl-DL-tryptophan also has the effect of reducing weight.

HY-W000438

N-Boc-O-tosyl hydroxylamine		99.55%
N-Boc-O-tosyl hydroxylamine is used as a safe and efficient nitrogen source for the N-amination of aryl and alkyl amines.

HY-131894

DL-Serine hydroxamate
DL-Serine hydroxamate is a serine derivative.

HY-141447

Z-LYS-SBZL monohydrochloride		99.83%
Z-LYS-SBZL (monohydrochloride) is a lysine derivative.

HY-79648

Fmoc-Aib-OH		99.90%
Fmoc-Aib-OH is an alanine derivative.

HY-W013780

Fmoc-Pro-OH		99.97%
Fmoc-Pro-OH is a proline derivative.

HY-W099595

Ethyl Lauroyl Arginate Hydrochloride		99.23%
Ethyl Lauroyl Arginate Hydrochloride is an arginine derivative.

HY-W000795

(S)-2-amino-3-(4-benzoylphenyl)propanoic acid		99.47%
(S)-2-amino-3-(4-benzoylphenyl)propanoic acid is an alanine derivative.

HY-W008475

Fmoc-Glu-OAll		98.92%
Fmoc-Glu-OAll is a glutamic acid derivative.

HY-101404A

L-Homocysteine thiolactone hydrochloride		99.99%
L-Homocysteine thiolactone hydrochloride is an intramolecular thioester of Homocysteine. Homocysteine thiolactone hydrochloride prevents translational incorporation of homocysteine into proteins. L-Homocysteine thiolactone hydrochloride can induce elevated HHcy (hyperhomocysteinemia) in mice.

HY-W010732

Fmoc-L-Lys(ivDde)-OH		99.87%
Fmoc-L-Lys(ivDde)-OH is a lysine derivative.

HY-W048704

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((4-methoxyphenyl)diphenylmethyl)-L-lysine		98.07%
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-((4-methoxyphenyl)diphenylmethyl)-L-lysine is a lysine derivative.

HY-W009592

Glycyl-L-tyrosine		99.59%
Glycyl-L-tyrosine is a synthetic dipeptide that can be used as a food additive for tyrosine supplementation.

HY-134669

CypK		98.30%
CypK (N-Cyclopropene-L-Lysine), a cyclopropene derivative of lysine, is efficiently incorporated into antibodies through genetic-code expansion. CypK is a minimal bioorthogonal handle for the creation of stable therapeutic protein conjugates.

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