Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W110126

(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid		99.18%
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid is a lysine derivative.

HY-I0423

3-(2-Thienyl)-D-alanine		99.88%
3-(2-Thienyl)-D-alanine is an alanine derivative.

HY-113214

3,5-Diiodo-L-tyrosine		99.19%
3,5-Diiodo-L-tyrosine is a tyrosine derivative.

HY-129847

Alitame		99.79%
Alitame is a high-intensity sweetener formed from the amino acids L-aspartic acid and D-alanine, and an amine derived from thietane.

HY-B1258

4-(Aminomethyl)benzoic acid		99.99%
4-(Aminomethyl)benzoic acid is a competitive inhibitor of PepT1 and has antifibrinolytic activity.

HY-P2405

Fmoc-Gly-Ser(psi(Me,Me)pro)-OH		99.78%
Fmoc-Gly-Ser(psi(Me,Me)pro)-OH is a dipeptide.

HY-101877

Statine		99.83%
Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases.

HY-W048913

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-(2-((5-sulfonaphthalen-1-yl)amino)ethyl)-L-glutamine		98.12%
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-(2-((5-sulfonaphthalen-1-yl)amino)ethyl)-L-glutamine is a glutamine derivative.

HY-W011001

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclohexylpropanoic acid		99.83%
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclohexylpropanoic acid is an alanine derivative.

HY-W091734

Methyl 4-iodo-L-phenylalaninate hydrochloride
Methyl 4-iodo-L-phenylalaninate hydrochloride is a Phenylalaninate derivative. Methyl 4-iodo-L-phenylalaninate hydrochloride can be used for the preparation of factor XI modulators used in the research of thrombotic and thromboembolic. Methyl 4-iodo-L-phenylalaninate hydrochloride can also be used for the synthesis of compounds for the research of amyloid-related diseases, such as Alzheimer’s disease.

HY-W013734

N,N'-Di-BOC-L-cystine
N,N'-Di-BOC-L-cystine is a cysteine derivative.

HY-W040686

2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid
2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid is a Glycine (HY-Y0966) derivative.

HY-N2378

(2R,3S)-3-Phenylisoserine hydrochloride
(2R,3S)-3-Phenylisoserine hydrochloride is a serine derivative.

HY-79415

4-Methyl-L-leucine
4-Methyl-L-leucine is a Glycine (HY-Y0966) derivative.

HY-W141922

N-(Methylsulfonyl)glycine
N-(Methylsulfonyl)glycine is a Glycine (HY-Y0966) derivative.

HY-W010894

Fmoc-D-2-Nal-OH		99.89%
Fmoc-D-2-Nal-OH is an alanine derivative.

HY-W009562

H-Met-OtBu.HCl		≥98.0%
H-Met-OtBu.HCl is a Methionine (HY-13694) derivative.

HY-I0393

3-(2-Thienyl)-L-alanine		99.66%
3-(2-Thienyl)-L-alanine is an alanine derivative.

HY-42356

Methyl (2R)-2-amino-2-cyclohexylethanoate hydrochloride		≥98.0%
Methyl (2R)-2-amino-2-cyclohexylethanoate hydrochloride is a Glycine (HY-Y0966) derivative.

HY-W141774

S-(2-Carboxyethyl)-L-cysteine		98.64%
S-(2-Carboxyethyl)-L-cysteine (S-Carboxyethylcysteine) is a non-protein (modified) sulfur amino acid. S-(2-Carboxyethyl)-L-cysteine is present in Acacia seed. S-(2-Carboxyethyl)-L-cysteine can affect the seed’s protein use in rats. S-(2-Carboxyethyl)-L-cysteine suppresses the methionine-induced growth rate, and has a negative effect on the plasma amino acid levels in rats.

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