Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1608):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W013154

Fmoc-Tic-OH		99.83%
Fmoc-Tic-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as the biotinylated derivative of the opioid receptor antagonist TIPP.

HY-W011903

H-Ala-Tyr-OH		99.78%
H-Ala-Tyr-OH is a tyrosine derivative.

HY-W010724

Fmoc-D-Cys(Trt)-OH		99.37%
Fmoc-D-Cys(Trt)-OH is a cysteine derivative.

HY-W010719

Fmoc-D-Asn(Trt)-OH		99.89%
N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-D-asparagine is an asparagine derivative.

HY-W008178

(R)-2-((tert-Butoxycarbonyl)amino)-3-(tritylthio)propanoic acid		99.87%
(R)-2-((tert-Butoxycarbonyl)amino)-3-(tritylthio)propanoic acid is a cysteine derivative.

HY-W013779

Fmoc-D-Gly(allyl)-OH		99.98%
Fmoc-D-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative.

HY-W009023

Fmoc-D-4-Pal-OH		99.29%
Fmoc-D-4-Pal-OH is an alanine derivative.

HY-W048697

Fmoc-D-Pen(Trt)-OH
Fmoc-D-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize analogs of cyclic lanthionine enkephalin, a δ-opioid receptor selective ligand.

HY-W009912

H-Tyr(Me)-OH		99.74%
H-Tyr(Me)-OH is a synthetic amino acid, and can enter into protein in E. coli in response to an amber nonsense codon.

HY-W012437

Boc-Thr-OH
Boc-Thr-OH is a threonine derivative.

HY-W142062

cis-Fmoc-Pro(4-N3)-OH		99.13%
cis-Fmoc-Pro(4-N3)-OH is a proline derivative. cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W048703

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-tyrosine		99.50%
(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-tyrosine is a tyrosine derivative.

HY-W013968

Boc-Gly-Gly-OH		99.46%
Boc-Gly-Gly-OH is a Glycine (HY-Y0966) derivative.

HY-W009005

Fmoc-HoPhe-OH		99.71%
Fmoc-HoPhe-OH is a phenylalanine derivative.

HY-W002326

Boc-Asp(OtBu)-OH		99.78%
Boc-Asp(OtBu)-OH is an aspartic acid derivative.

HY-W050025

6-Chloro-L-tryptophan		99.50%
6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ.

HY-17490

Oxaceprol		99.70%
Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis.

HY-W008908

Fmoc-Tyr(H2PO3)-OH		99.22%
Fmoc-Tyr(H2PO3)-OH is a tyrosine derivative.

HY-Z0438

Boc-L-Ile-OH		98.0%
Boc-L-Ile-OH is an isoleucine derivative.

HY-W008467

(S)-2-amino-3-hydroxy-2-methylpropanoic acid		98.0%
(S)-2-amino-3-hydroxy-2-methylpropanoic acid is a serine derivative.

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