Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-134852

Fmoc-Cys(STmp)-OH		98.93%
Fmoc-Cys(STmp)-OH is a cysteine derivative.

HY-W022227

Fmoc-D-Tyr(Me)-OH		99.56%
Fmoc-D-Tyr(Me)-OH is a phenylalanine derivative.

HY-79130

Fmoc-(S)-phenylglycine		99.95%
Fmoc-(S)-phenylglycine is a Glycine (HY-Y0966) derivative.

HY-77801

(R)-2-Amino-4-mercaptobutanoic acid		≥98.0%
(R)-2-Amino-4-mercaptobutanoic acid is a cysteine derivative.

HY-A0282

L-Ornithine L-aspartate		≥98.0%
L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids with oral activity: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. L-Ornithine L-aspartate also improves mitochondrial functions.

HY-W013144

Fmoc-D-Asp(OtBu)-OH		99.18%
Fmoc-D-Asp(OtBu)-OH is an aspartic acid derivative.

HY-65000

H-Lys(Boc)-OMe hydrochloride		≥98.0%
H-Lys(Boc)-OMe hydrochloride is a lysine derivative.

HY-32687A

L-Serine methyl ester hydrochloride		99.56%
L-Serine methyl ester (hydrochloride) is a serine derivative.

HY-W011199

Boc-Tyr(tBu)-OH		99.94%
Boc-Tyr(tBu)-OH is a tyrosine derivative.

HY-134450

L-Aspartic acid β-hydroxamate		≥98.0%
L-Aspartic acid β-hydroxamate is an aspartic acid derivative.

HY-119543

O-Succinyl-L-homoserine		≥98.0%
O-Succinyl-L-homoserine is a homoserine derivative. O-Succinyl-L-homoserine is an intermediate in the biosynthesis of methionine in Escherichia coli and Salmonella typhimurium.

HY-W013779

Fmoc-D-Gly(allyl)-OH		99.98%
Fmoc-D-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative.

HY-W009023

Fmoc-D-4-Pal-OH		99.29%
Fmoc-D-4-Pal-OH is an alanine derivative.

HY-W009912

H-Tyr(Me)-OH		99.74%
H-Tyr(Me)-OH is a synthetic amino acid, and can enter into protein in E. coli in response to an amber nonsense codon.

HY-W012437

Boc-Thr-OH
Boc-Thr-OH is a threonine derivative.

HY-W142062

cis-Fmoc-Pro(4-N3)-OH		99.13%
cis-Fmoc-Pro(4-N3)-OH is a proline derivative. cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W008235

Fmoc-N-Me-Ala-OH		99.87%
Fmoc-N-Me-Ala-OH, an N-Fmoc-N-methyl amino acid, is available for the peptide-coupling reaction.

HY-W048703

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-tyrosine		99.50%
(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-tyrosine is a tyrosine derivative.

HY-42709

Z-Val-Ala-OH		99.78%
Z-Val-Ala-OH is a dipeptide derivative of valine and alanine.

HY-W013968

Boc-Gly-Gly-OH		99.46%
Boc-Gly-Gly-OH is a Glycine (HY-Y0966) derivative.

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