Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1608):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-20897A

5-Bromo-L-tryptophan		99.60%
5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236).

HY-W013998

Glycyl-L-phenylalanine		99.74%
Glycyl-L-phenylalanine is a phenylalanine derivative.

HY-W013163

(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropanoic acid		99.74%
(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropanoic acid is a phenylalanine derivative.

HY-W041992

Fmoc-β-cyclopropyl-L-Alanine		99.89%
Fmoc-β-cyclopropyl-L-Alanine is an alanine derivative.

HY-W041867

Boc-Ser-OtBu		98.0%
Boc-Ser-OtBu is a serine derivative.

HY-32687A

L-Serine methyl ester hydrochloride		99.56%
L-Serine methyl ester (hydrochloride) is a serine derivative.

HY-B1732

DL-3-Phenylalanine		99.99%
DL-3-Phenylalanine is a phenylalanine derivative.

HY-W022223

Fmoc-3-Chloro-L-phenylalanine		98.97%
Fmoc-3-Chloro-L-phenylalanine is a phenylalanine derivative.

HY-59140

(S)-2-Amino-3,3-dimethylbutanoic acid		≥98.0%
(S)-2-amino-3,3-dimethylbutanoic acid is a leucine derivative.

HY-Y0749

Glutamic acid dimethyl ester hydrochloride
Glutamic acid dimethyl ester hydrochloride is a glutamic acid derivative.

HY-W013740

Fmoc-N-Me-Asp(OtBu)-OH		99.64%
Fmoc-N-Me-Asp(OtBu)-OH is an aspartic acid derivative.

HY-W013750

Fmoc-Arg-OH		99.95%
Fmoc-Arg-OH (Fmoc-L-Arginine), an Fmoc modified Arginine, is used in peptide synthesis.

HY-W007722

H-Ala-OtBu.HCl		≥98.0%
H-Ala-OtBu.HCl is an alanine derivative.

HY-41257

Boc-L-Tyrosine methyl ester		99.97%
Boc-L-Tyrosine methyl ester is a tyrosine derivative.

HY-W001158S

N,N-Dimethylglycine-d₆ hydrochloride		99.46%
N,N-Dimethylglycine-d₆ (Dimethylglycine-d₆) hydrochloride is the deuterium labeled N,N-Dimethylglycine hydrochloride (HY-W001158). N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects.

HY-W102456

H-Phe(4-Ac)-OH		99.19%
H-Phe(4-Ac)-OH (L-4-Acetylphenylalanine) is a keto-amino acid that can be converted from α-keto acids containing an acetyl group. H-Phe(4-Ac)-OH can be added to the amber position to form mutant Z-domain proteins. H-Phe(4-Ac)-OH is used as a functional amino acid in peptide modification to achieve chemical bonding between peptides and solid surfaces.

HY-W008694

N-Benzoyl-L-arginine ethyl ester hydrochloride		98.18%
N-Benzoyl-L-arginine ethyl ester hydrochloride is an arginine derivative.

HY-P1851A

AGA-(C8R) HNG17, humanin derivative TFA		98.34%
AGA-(C8R) HNG17, humanin derivative TFA is a potent humanin (HN) derivative. AGA-(C8R) HNG17, humanin derivative completely suppresses neuronal cell death by Alzheimer's disease-relevant insults.

HY-W013749

Fmoc-N-Me-Ser(tBu)-OH		99.84%
Fmoc-N-Me-Ser(tBu)-OH is a serine derivative.

HY-W048825

Fmoc-Ala-Ala-OH		99.35%
Fmoc-Ala-Ala-OH (3) is a self-assemble fluorenylmethoxycarbonyl-dipeptide, which is a smaller amphiphilic building blocks consists dipeptides linked to fluore nylmethoxycarbonyl (Fmoc). Fmoc-Ala-Ala-OH can be used as scaffold materials in 3D cell culture.

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