Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Chemical (1)

Amino Acid Derivatives Related Products (1590):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W009686

L-Prolyl-L-leucine		99.87%
L-Prolyl-L-leucine is a leucine derivative.

HY-Y1801

β-Methyl L-aspartate hydrochloride		≥98.0%
β-Methyl L-aspartate hydrochloride is an aspartic acid derivative.

HY-W045221

(R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)pyrrolidin-2-yl)acetic acid		99.96%
(R)-2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)pyrrolidin-2-yl)acetic acid is a proline derivative.

HY-W016443

L-m-Tyrosine		99.94%
L-m-Tyrosine is an unnatural amino acid. L-m-Tyrosine reduces dopamine, norepinephrine and serotonin in rats. L-m-Tyrosine has potential in the research of Parkinsons disease, Alzheimers disease, and arthritis.

HY-W048207

N6-Propionyl-L-lysine		99.86%
N6-Propionyl-L-lysine is a lysine derivative.

HY-W006185

(S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride
(S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride is a glutamic acid derivative.

HY-W011056

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(furan-2-yl)propanoic acid		99.66%
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(furan-2-yl)propanoic acid is an alanine derivative.

HY-W010838

Fmoc-D-Bip(4,4’)-OH		99.57%
Fmoc-D-Bip(4,4’)-OH is an alanine derivative.

HY-W014375S2

Arginine-¹³C₆ hydrochloride		99.00%
Arginine-¹³C₆ hydrochloride is ¹³C-labeled Arginine (hydrochloride) (HY-W014375). Arginine hydrochloride is an arginine derivative.

HY-66025

Fmoc-Lys(Me)2-OH hydrochloride
Fmoc-Lys(Me)2-OH HCl is a lysine derivative.

HY-B1169

Timonacic		≥98.0%
Timonacic (1,3-Thiazolidine-4-carboxylic acid) is an orally active thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects. Timonacic has a LD₅₀ of 400 mg/kg for mice. Timonacic can be used in the research of liver diseases, gastrointestinal diseases, and cancer.

HY-W010719

Fmoc-D-Asn(Trt)-OH		99.89%
N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-D-asparagine is an asparagine derivative.

HY-W013143

Fmoc-Cys(Acm)-OH		99.33%
Fmoc-Cys(Acm)-OH is a cysteine derivative.

HY-W018502

4-Aminobutylphosphonic acid		≥98.0%
4-Aminobutylphosphonic acid is aamino acids and their derivatives.

HY-Y1789

Methyl 2-aminoacetate hydrochloride		≥98.0%
Methyl 2-aminoacetate hydrochloride is a Glycine (HY-Y0966) derivative.

HY-41257

Boc-L-Tyrosine methyl ester		99.97%
Boc-L-Tyrosine methyl ester is a tyrosine derivative.

HY-W102456

H-Phe(4-Ac)-OH		99.19%
H-Phe(4-Ac)-OH (L-4-Acetylphenylalanine) is a keto-amino acid that can be converted from α-keto acids containing an acetyl group. H-Phe(4-Ac)-OH can be added to the amber position to form mutant Z-domain proteins. H-Phe(4-Ac)-OH is used as a functional amino acid in peptide modification to achieve chemical bonding between peptides and solid surfaces.

HY-34597

(S)-2-Amino-3-(4-bromophenyl)propanoic acid		99.91%
(S)-2-Amino-3-(4-bromophenyl)propanoic acid is a phenylalanine derivative.

HY-W010734

Fmoc-Ser(Trt)-OH		99.97%
Fmoc-Ser(Trt)-OH is a serine derivative.

HY-W013155

H-His(Trt)-OH		99.98%
H-His(Trt)-OH is a histidine derivative.

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