1. Signaling Pathways
  2. Stem Cell/Wnt
  3. Wnt
  4. Wnt Isoform
  5. Wnt Modulator

Wnt Modulator

Wnt Modulators (5):

Cat. No. Product Name Effect Purity
  • HY-10593
    IQ 1
    Modulator 99.13%
    IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin-driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP-mediated transcription and preventing conversion to β-catenin/p300-mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion.
  • HY-P4858
    C-Peptide 1 (rat)
    Modulator 99.88%
    C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer.
  • HY-126248
    Tankyrase-IN-2
    Modulator 99.06%
    Tankyrase-IN-2 (compound 5k) is a potent, selective, and orally active tankyrase inhibitor (IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectively). Tankyrase-IN-2 has favorable physicochemical profile and pharmacokinetic properties modulating Wnt pathway activity in a colorectal xenograft model.
  • HY-N7171
    4,4'-Di-O-methylellagic acid
    Modulator
    4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) can be isolated from the Australian termites. 4,4'-Di-O-methylellagic acid is blue-fluorescent under ultra-violet light. 4,4'-Di-O-methylellagic acid inhibits colon cancer cell proliferation via the wnt signal pathway.
  • HY-169508
    BMD4503-1
    Modulator
    BMD4503-1 is a quinoxaline derivative. BMD4503-1 can inhibit the LRP5/6-Sclerostin interaction and regulate the Wnt signaling pathway.