2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. TMPRSS6

TMPRSS6

Matriptase-2; Transmembrane protease serine 6

TMPRSS6 (Matriptase-2) is a serine protease highly expressed in the liver. TMPRSS6 functions as a negative regulator of the expression of the systemic iron-regulatory hormone hepcidin.

TMPRSS6 Related Products (2):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-147278A
    Manusiran sodium
    		Inhibitor
    Manusiran (SLN124) sodium, a GalNAc conjugated 19-mer siRNA targeting TMPRSS6 (transmembrane protease serine 6), reduces plasma iron and increases hepcidin levels[1][2].
    Manusiran sodium
  • HY-147278
    Manusiran
    		Inhibitor
    Manusiran (SLN124), a GalNAc conjugated 19-mer siRNA targeting TMPRSS6 (transmembrane protease serine 6), reduces plasma iron and increases hepcidin levels of healthy volunteers[1][2].
    Manusiran