2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. SGK
  5. SGK Isoform

SGK

 

SGK Related Products (14):

Cat. No. Product Name Effect Purity
  • HY-145752
    HaloPROTAC-E
    		Inhibitor 98.18%
    HaloPROTAC-E is a potent Halo PROTAC degrader that reversibly induces degradation of two Halo-tagged endoplasmic reticulum-localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM. HaloPROTAC-E significantly and selectively induces degradation of endogenous VPS34 complexes (VPS34, VPS15, Beclin1, and ATG14) labeled with Halo and inhibits autophagy.
  • HY-117357
    SI-113
    		Inhibitor 98.02%
    SI-113 is a SGK1 inhibitor, with an IC50 of 600 nM. SI113 induces autophagy.
  • HY-142687
    SGK1-IN-4
    		Inhibitor 99.80%
    SGK1-IN-4 (compound 17a) is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for osteoarthritis research.
  • HY-135893
    SGK1-IN-2
    		Inhibitor 98.36%
    SGK1-IN-2 (14h) is a selective SGK1 (serum and glucocorticoid regulated kinase 1) inhibitor, with an IC50 of 5 nM at 10 μM ATP concentration.
  • HY-15193B
    EMD638683 S-Form
    		Inhibitor 99.95%
    EMD638683 S-Form is the S-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.
  • HY-15193A
    EMD638683 R-Form
    		Inhibitor 99.86%
    EMD638683 R-Form is the R-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.
  • HY-RS12800
    Sgk1 Rat Pre-designed siRNA Set A
    		Inhibitor

    Sgk1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sgk1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS12799
    Sgk1 Mouse Pre-designed siRNA Set A
    		Inhibitor

    Sgk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sgk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-142686A
    SGK1-IN-3 hydrochloride
    		Inhibitor
    SGK1-IN-3 hydrochloride (compound 3a) is a potent SGK1 inhibitor with an IC50 of <1 μM. SGK1-IN-3 hydrochloride has the potential for the research of osteoarthritis.
  • HY-RS12803
    Sgk3 Mouse Pre-designed siRNA Set A
    		Inhibitor

    Sgk3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sgk3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-RS12798
    SGK1 Human Pre-designed siRNA Set A
    		Inhibitor

    SGK1 Human Pre-designed siRNA Set A contains three designed siRNAs for SGK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
  • HY-15192R
    GSK 650394 (Standard)
    		Inhibitor
    GSK 650394 (Standard) is the analytical standard of GSK 650394. This product is intended for research and analytical applications. GSK 650394 is a novel SGK inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2 in the SPA assay respectively. GSK 650394 also inhibits influenza virus replication.
  • HY-15193R
    EMD638683 (Standard)
    		Inhibitor
    EMD638683 (Standard) is the analytical standard of EMD638683. This product is intended for research and analytical applications. EMD638683 is a highly selective SGK1 inhibitor, with an IC50 value of 3 μM.
  • HY-128221
    SGK1-IN-5
    		Inhibitor
    SGK1-IN-5 (Compound 1) is an inhibitor for serum and glucocorticoid regulated kinase SGK 1 with an IC50 of 3 nM. SGK1-IN-5 inhibits SGK-1 dependent phosphorylation of GSK3β in U2OS cells with an IC50 of 1.4 μM. SGK1-IN-5 can be used in research about osteoarthritis or rheumatism.