2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Renin
  5. Renin Antagonist

Renin Antagonist

Renin Antagonists (3):

Cat. No. Product Name Effect Purity
  • HY-P10933
    PRO20
    		Antagonist
    PRO20 is a specific and competitive (pro)renin receptor (PRR) antagonist. PRO20 inhibits Prorenin-induced calcium influx with an IC50 value of 81 nmol/L. PRO20 exerts antihypertensive activity by blocking the binding of prorenin to the PRR, inhibiting the activation of the renin-angiotensin system (RAS), and reducing the production of angiotensin II (Ang II). PRO20 is promising for research of antihypertensive agents.
  • HY-P2075
    EMD 55068
    		Antagonist
    EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate.
  • HY-P1572
    Handle region peptide, rat
    		Antagonist
    Handle region peptide, rat is a prorenin receptor antagonist, suppresses the progression of diabetic nephropathy and has anti-inflammatory in the eye.