2. Signaling Pathways
  3. Apoptosis
  4. RIP kinase
  5. RIPK1 Isoform
  6. RIPK1 Degrader

RIPK1 Degrader

RIPK1 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-175370
    PROTAC RIPK1 Degrader-1
    		Degrader
    PROTAC RIPK1 Degrader-1 is a selective RIPK1 PROTAC degrader. PROTAC RIPK1 Degrader-1 degrades RIPK1 in multiple cancer cell lines (e.g., A375, B16F10 cells). PROTAC RIPK1 Degrader-1 enhances the anti-cancer effect of radiotherapy in syngeneic and humanized mouse models. PROTAC RIPK1 Degrader-1 can be used to study cancers such as melanoma. (Pink: RIPK1-ligand-2: HY-175371, Blue: (S,R,S)-AHPC-Me: HY-112078, Pink + Black: RIPK1 ligand-Linker Conjugate-1: HY-175374, Black: Bispiperidin-piperazin-acetater: HY-175373).