1. Signaling Pathways
  2. Cell Cycle/DNA Damage
    Cytoskeleton
  3. PAK
  4. PAK4 Isoform
  5. PAK4 Degrader

PAK4 Degrader

PAK4 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-174247
    CPS-021
    Degrader
    CPS-021 is a selective PAK4 PROTAC degrader with a DC50 of 50 nM. CPS-021 has potent antimigratory and invasive activity and significantly suppresses the invasion and metastasis of tumor cells in A549-luc lung metastasis mice model. Pink: PAK4 ligand (HY-174822); Blue: CRBN ligase ligand (HY-10984); Black: linker