2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-134216
    MAHMA NONOate
    MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP.
    MAHMA NONOate
  • HY-W013935
    Bisphenol B
    		99.34%
    Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties.
    Bisphenol B
  • HY-P2985
    Alanine aminotransferase, Porcine heart
    Alanine aminotransferase, Porcine heart is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate.
    Alanine aminotransferase, Porcine heart
  • HY-E70285
    beta-1,4-Galactosyltransferase 1 (Y285L)
    beta-1,4-Galactosyltransferase 1 (Y285L) can enzymatic synthesis of the LacdiNAc motif. beta-1,4-Galactosyltransferase 1 (Y285L) can transfer of GalNAc from UDP-GalNAc.
    beta-1,4-Galactosyltransferase 1 (Y285L)
  • HY-101400A
    Deoxycytidine triphosphate (trisodium) solution (100mM)
    		99.46%
    Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
    Deoxycytidine triphosphate (trisodium) solution (100mM)
  • HY-W353102
    Estradiol 17-(β-D-Glucuronide)
    		99.0%
    Estradiol 17-(β-D-Glucuronide), a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans. Estradiol 17-(β-D-Glucuronide) is a high-affinity substrate for oatp organic anion transporter.
    Estradiol 17-(β-D-Glucuronide)
  • HY-18341A
    L-Thyroxine sodium salt pentahydrate
    		99.91%
    L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
    L-Thyroxine sodium salt pentahydrate
  • HY-112052
    Aminomalonic acid
    		98.87%
    Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis.
    Aminomalonic acid
  • HY-B0228S13
    Adenosine-13C10
    		99.63%
    Adenosine-13C10 (Adenine riboside-13C10; D-Adenosine-13C10) is 13C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
    Adenosine-<sup>13</sup>C<sub>10</sub>
  • HY-113437A
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium
    		98.0%
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite. It is used in the generation of micelles, liposomes, and artificial membranes.
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium
  • HY-W009390
    DL-Homocystine
    		98.0%
    DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia.
    DL-Homocystine
  • HY-W016823S
    p-Tyramine-d4 hydrochloride
    		≥99.90%
    p-Tyramine-d4 (hydrochloride) is the deuterium labeled Tyramine hydrochloride. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods.
    p-Tyramine-d<sub>4</sub> hydrochloride
  • HY-N2543
    Damascenone
    		99.26%
    Damascenone ((E/Z)-Damascenone) is an active compound of Epipremnum pinnatum with anti-inflammatory activity. Damascenone is a mixture complex of E-isomer-Damascenone and Z-isomer Damascenone.
    Damascenone
  • HY-N0455AS2
    L-Arginine-d7 hydrochloride
    		99.72%
    L-Arginine-d7 (hydrochloride) is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
    L-Arginine-d<sub>7</sub> hydrochloride
  • HY-121705
    Propionyl-L-carnitine
    Propionyl-L-carnitine is an orally active L-carnitine derivative. Propionyl-L-carnitine has a high affinity for muscle L-carnitine transferase. Propionyl-L-carnitine increases Apoptosis, Bax, and reduces NF-κB, VCAM-1, MCP-1, and survivin. Propionyl-L-carnitine activates Src kinase, Akt, induces p-AMPK and nitric oxide synthesis. Propionyl-L-carnitine alleviates cardiovascular disease, obesity, and colitis.
    Propionyl-L-carnitine
  • HY-W001171R
    3-Hydroxyanthranilic acid (Standard)
    3-Hydroxyanthranilic acid (Standard) is the analytical standard of 3-Hydroxyanthranilic acid. This product is intended for research and analytical applications. 3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.
    3-Hydroxyanthranilic acid (Standard)
  • HY-135867E
    NHC-triphosphate tetraammonium
    NHC-triphosphate tetraammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a triphosphate form. NHC-triphosphate tetraammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA.
    NHC-triphosphate tetraammonium
  • HY-Y0966S1
    Glycine-d2
    		99.92%
    Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
    Glycine-d<sub>2</sub>
  • HY-P2869
    β-Galactosidase, E. coli
    β-Galactosidase (EC 3.2.1.23) is a glycoside hydrolase that hydrolyzes the β-glycosidic bonds formed between galactose and its organic moieties. In E.coli, the lacZ gene is the structural gene of β-galactosidase, which can be used as part of the induction system lac operon. β-Galactosidase can hydrolyze lactose to form glucose and galactose, and enter glycolysis; it can also catalyze the transgalactosylation of lactose into allolactose; allolactose can be cracked into monosaccharides.
    β-Galactosidase, E. coli
  • HY-134424
    Propionyl coenzyme A lithium
    Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms.
    Propionyl coenzyme A lithium
Cat. No. Product Name / Synonyms Application Reactivity