2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113437A
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium
    		98.0%
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium (compound 3-F7) is a phosphatidic acid and a human endogenous metabolite. It is used in the generation of micelles, liposomes, and artificial membranes.
    1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium
  • HY-B0228S6
    Adenosine-d2
    		99.56%
    Adenosine-d2 is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio
    Adenosine-d<sub>2</sub>
  • HY-W007686
    Imidazoleacetic acid hydrochloride
    		99.65%
    Imidazoleacetic acid hydrochloride is a γ-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a Ki value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain.
    Imidazoleacetic acid hydrochloride
  • HY-N2543
    Damascenone
    		99.26%
    Damascenone ((E/Z)-Damascenone) is an active compound of Epipremnum pinnatum with anti-inflammatory activity. Damascenone is a mixture complex of E-isomer-Damascenone and Z-isomer Damascenone.
    Damascenone
  • HY-121705
    Propionyl-L-carnitine
    Propionyl-L-carnitine is an orally active L-carnitine derivative. Propionyl-L-carnitine has a high affinity for muscle L-carnitine transferase. Propionyl-L-carnitine increases Apoptosis, Bax, and reduces NF-κB, VCAM-1, MCP-1, and survivin. Propionyl-L-carnitine activates Src kinase, Akt, induces p-AMPK and nitric oxide synthesis. Propionyl-L-carnitine alleviates cardiovascular disease, obesity, and colitis.
    Propionyl-L-carnitine
  • HY-118103
    Coprostanol
    		99.1%
    Coprostanol (Coprostan-3-ol) is a fecal sterol formed by microbial reduction of cholesterol in the intestines of man and higher animals. Coprostanol can be used as an indicator sterol of fecal pollution. Coprostanol has been recognized as a good indicator of pollution of water resources by sewage discharges.
    Coprostanol
  • HY-128742
    Thiamine monophosphate (chloride) dihydrate
    		99.24%
    Thiamine monophosphate chloride dehydrate is a source of Vitamin B1 (HY-A0100). Thiamine monophosphate chloride involves being absorbed and converted to thiamine in the body. Thiamine monophosphate chloride is mainly used in the research of food supplements as a vitaminB1 source to meet the nutritional needs of the body.
    Thiamine monophosphate (chloride) dihydrate
  • HY-Y0966S1
    Glycine-d2
    		99.92%
    Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
    Glycine-d<sub>2</sub>
  • HY-N1363
    Royal Jelly acid
    		99.42%
    Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases.
    Royal Jelly acid
  • HY-N0455B
    L-Arginine (L-glutamate)
    		98.0%
    L-Arginine L-glutamate ((S)-(+)-Arginine L-glutamate) is the nitrogen donor for synthesis of nitric oxide. L-Arginine L-glutamate can be used for upper gastrointestinal hypofunction or dysfunction like functional dyspepsia research.
    L-Arginine (L-glutamate)
  • HY-113066C
    Guanosine 5'-diphosphate (sodium), 96% (HPLC)
    		99.88%
    Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI).
    Guanosine 5'-diphosphate (sodium), 96% (HPLC)
  • HY-30152
    Xanthotoxol
    		99.46%
    Xanthotoxol (8-Hydroxypsoralen) It is a kind of fragrant bean substance, and it is a CYP450 inhibitor. Xanthotoxol has anti-inflammatory, anti-inflammatory, and 5-HT antagonistic and protective effects. Xanthotoxol inhibited CYP3A4 sum CYP1A2 IC50s separation 7.43 μM sum 27.82 μM. Xanthotoxol can pass through MAPK and NF-κB, inhibiting inflammation.
    Xanthotoxol
  • HY-113373
    Guanidinosuccinic acid
    		98.0%
    Guanidinosuccinic acid is a nitrogenous metabolite.
    Guanidinosuccinic acid
  • HY-W010381
    2-Methylsuccinic acid
    		98.0%
    2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.
    2-Methylsuccinic acid
  • HY-N0541
    Pseudoginsenoside F11
    		99.87%
    Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice.
    Pseudoginsenoside F11
  • HY-W014130
    N-Acetyl-L-arginine
    		99.97%
    N-Acetyl-L-arginine (Ac-Arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population. N-Acetyl-L-arginine shows synergistic activity with glycine buffer. N-Acetyl-L-arginine suppresses the aggregation of intravenous immunoglobulins with a minimum decrease in transition temperature. N-Acetyl-L-arginine dramatically reduces IL-1 expression in the presence of silicone oil. N-Acetyl-L-arginine also demonstrates colloidal stability.
    N-Acetyl-L-arginine
  • HY-Y1309
    1-Naphthol
    		99.96%
    1-naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media.
    1-Naphthol
  • HY-N0913
    Manninotriose
    		99.97%
    Manninotriose is a novel and important player in the RFO(Raffinose family oligosaccharides) metabolism of red dead deadnettle; potential to improve the side effects of MTX for ALL treatment.
    Manninotriose
  • HY-113284
    Succinyladenosine
    		99.43%
    Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency.
    Succinyladenosine
  • HY-Y0966S3
    Glycine-13C2
    		99.10%
    Glycine-13C2 is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
    Glycine-<sup>13</sup>C<sub>2</sub>
Cat. No. Product Name / Synonyms Application Reactivity