2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N1423A
    Glycocholic acid sodium
    Glycocholic acid sodium is an orally active bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways.
    Glycocholic acid sodium
  • HY-W009390
    DL-Homocystine
    		98.0%
    DL-Homocystine is the double-bonded form of homocysteine and homocysteine is recognized as an important substance in the pathogenesis and pathophysiology of schizophrenia.
    DL-Homocystine
  • HY-113344
    16α-Hydroxyestrone
    		99.74%
    16α-Hydroxyestrone (16αOHE) is a major Estradiol metabolite. 16α-Hydroxyestrone (16αOHE) can be used for the research of metabolic disease.
    16α-Hydroxyestrone
  • HY-W011956
    6-Hydroxymelatonin
    		99.81%
    6-Hydroxymelatonin is a primary metabolic of Melatonin, which is metabolized by cytochrome P450 (CYP) 1A2.
    6-Hydroxymelatonin
  • HY-113405
    21-Deoxycortisol
    		99.62%
    21-Deoxycortisol is an endogenous metabolite. 21-Deoxycortisol is a sign of congenital adrenal hyperplasia.
    21-Deoxycortisol
  • HY-109590S
    Arachidonic acid-d8
    		99.2%
    Arachidonic acid-d8 is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.
    Arachidonic acid-d<sub>8</sub>
  • HY-113165A
    Isobutyryl-L-carnitine chloride
    		98.0%
    Isobutyryl-L-carnitine chloride is a product of the acyl-CoA dehydrogenases.
    Isobutyryl-L-carnitine chloride
  • HY-B0234R
    Estrone (Standard)
    Estrone (Standard) is the analytical standard of Estrone. This product is intended for research and analytical applications. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells.
    Estrone (Standard)
  • HY-N0729S2
    Linoleic acid-13C18
    		99.10%
    Linoleic acid-13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
    Linoleic acid-<sup>13</sup>C<sub>18</sub>
  • HY-W014180
    N-Acetyl-L-histidine monohydrate
    		99.96%
    N-Acetyl-L-histidine monohydrate, a histidine derivative, is a prominent biomolecule in brain, retina and lens of poikilothermic vertebrates. N-Acetyl-L-histidine monohydrate has a role as an animal metabolite.
    N-Acetyl-L-histidine monohydrate
  • HY-112779
    Pertussis Toxin
    		≥99.0%
    Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. Pertussis Toxin inhibits G protein-coupled receptor (GPR) signaling through Gi proteins.
    Pertussis Toxin
  • HY-101411
    4-Acetamidobutanoic acid
    		98.0%
    4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities.
    4-Acetamidobutanoic acid
  • HY-113469A
    Cyclic GMP sodium
    		99.89%
    Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses.
    Cyclic GMP sodium
  • HY-B1500
    2,2,2-Trichloroethanol
    		99.53%
    2,2,2-Trichloroethanol, the active form of Chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4).
    2,2,2-Trichloroethanol
  • HY-P0002
    Protirelin
    		99.98%
    Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.
    Protirelin
  • HY-N0666S8
    L-Aspartic acid-d3
    		99.9%
    L-Aspartic acid-d3 is the deuterium labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.
    L-Aspartic acid-d<sub>3</sub>
  • HY-Y0319G
    Magnesium acetate tetrahydrate
    		99.47%
    Magnesium acetate tetrahydrate is a carboxylic acid and short-chain fatty acid (SCFAs). Magnesium acetate tetrahydrate activates AMPK, increases ROS, cleaved caspase 9, PPARα, downregulates SREBP-1c, ChREBP expression. Magnesium acetate tetrahydrate exhibits antifungal activity against Saccharomyces cerevisiae W303-1A. Magnesium acetate tetrahydrate regulates energy metabolism. Magnesium acetate tetrahydrate has anticancer activity against gastric cancer. Magnesium acetate tetrahydrate induces writhing reaction and ulcerative colitis. Magnesium acetate tetrahydrate can be used in the researches for gastric cancer, ulcerative colitis, hepatic steatosis, and pain.
    Magnesium acetate tetrahydrate
  • HY-18569S3
    3-Indoleacetic acid-d7
    		99.84%
    3-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.
    3-Indoleacetic acid-d<sub>7</sub>
  • HY-W004461
    S-Methyl thiomethanesulfonate
    		99.87%
    S-Methyl thiomethanesulfonate (MMTS) is a sulfur-containing volatile organic compound produced by plants and bacteria and is an effective anti-oomycete agent.
    S-Methyl thiomethanesulfonate
  • HY-112537S1
    D-Glucose 6-Phosphate-13C6 disodium xhydrate
    		99.6%
    D-Glucose 6-Phosphate-13C6 disodium xhydrate is the 13C labeled D-Glucose 6-phosphate (HY-112537). D-Glucose 6-phosphate is a glucose sugar phosphorylated at the hydroxy group on carbon 6.
    D-Glucose 6-Phosphate-<sup>13</sup>C<sub>6</sub> disodium xhydrate
Cat. No. Product Name / Synonyms Application Reactivity