Endogenous Metabolite

Related Products

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite Related Products (8051)
Antibodies (477)

By Effects:	Controls (3) Inhibitors (57) Agonists (4) Antagonist (1) Activators (6) Modulators (9) Chemicals (11) Inducers (6)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-113308

Taurolithocholic acid		99.7%
Taurolithocholic acid is a bile acid that has the activity of increasing cell viability, inducing the S phase of the cell cycle, and promoting DNA synthesis in a concentration-dependent manner in the intrahepatic cholangiocarcinoma cell line RMCCA-1. It can also increase the phosphorylation of EGFR and ERK 1/2 and the expression of cyclin D1 in RMCCA-1 cells, and its induced RMCCA-1 cell growth can be inhibited by specific antagonists and inhibitors.

HY-W017386

3-Methyl-2-oxovaleric acid sodium		99.60%
3-Methyl-2-oxovaleric acid sodium is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid sodium is a biomarker of mustard airway diseases (MADs) and uric acid stone.

HY-B2221

Cellulose		98.9%
Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food.

HY-N0060B

(E)-Ferulic acid		99.89%
(E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-113217

Cholesteryl oleate		99.0%
Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing.

HY-N0455AS1

L-Arginine-¹⁵N₄ hydrochloride		99.94%
L-Arginine-¹⁵N₄ (hydrochloride) is the ¹⁵N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-118103

Coprostanol		99.1%
Coprostanol (Coprostan-3-ol) is a fecal sterol formed by microbial reduction of cholesterol in the intestines of man and higher animals. Coprostanol can be used as an indicator sterol of fecal pollution. Coprostanol has been recognized as a good indicator of pollution of water resources by sewage discharges.

HY-100618

Hispidin		99.85%
Hispidin, a PKC inhibitor and a phenolic compound can be found in Phellinus linteus, has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties.

HY-Y0124

NSC 16590
NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

HY-N0060A

Ferulic acid sodium		99.88%
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-Y0068

N-Acetyl-L-phenylalanine		99.98%
N-Acetyl-L-phenylalanine (N-Acetylphenylalanine) is a principal acylamino acid. N-Acetyl-L-phenylalanine can be synthesized from L-phenylalanine and acetyl-CoA. N-Acetyl-L-phenylalanine can be used in kidney research.

HY-W014180

N-Acetyl-L-histidine monohydrate		99.96%
N-Acetyl-L-histidine monohydrate, a histidine derivative, is a prominent biomolecule in brain, retina and lens of poikilothermic vertebrates. N-Acetyl-L-histidine monohydrate has a role as an animal metabolite.

HY-W012836

4-Ethylphenol		99.99%
4-Ethylphenol is a volatile phenolic compound associated with off-odour in wine. 4-Ethylphenol is a phenolic compound that can be synthesized by intestinal flora. 4-Ethylphenol will be converted to 4-ethylphenyl sulfate (HY-W674241) by Lactobacillus plantarum.

HY-P2861

Sarcosine oxidase, Bacillus
Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H₂O₂, 5,10-CH₂-tetrahydrofolate, which are often used in biochemical reactions.

HY-113469A

Cyclic GMP sodium		99.89%
Cyclic GMP (cGMP) sodium, an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP sodium occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses.

HY-W008820S

Glutaric acid-d₆		98.0%
Glutaric acid-d₆ is the deuterium labeled Glutaric acid. Glutaric acid is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I.

HY-N0299

Stachyose hydrate		98.0%
Stachyose hydrate is an orally active prebiotic that enhances the growth and activity of beneficial bacteria. Stachyose hydrate has hypoglycemic effects and can improve inflammation by regulating gut microbiota. In addition, Stachyose hydrate can induce plant cell apoptosis (Apoptosis). Stachyose hydrate can be used in research on inflammation, gastrointestinal diseases, and agriculture .

HY-N0666S8

L-Aspartic acid-d₃		99.9%
L-Aspartic acid-d₃ is the deuterium labeled L-Aspartic acid. L-Aspartic aicd is an amino acid that can penetrate the blood-brain barrier. L-Aspartic aicd is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd commonly used in the study of inflammatory conditions.

HY-113136

1-Methylguanosine		99.57%
1-Methylguanosine (N1-Methylguanosine) is a methylated nucleoside originating from RNA degradation. 1-Methylguanosine is a tumour marker.

HY-W011417

Cinnabarinic acid		99.86%
Cinnabarinic acid is a specific orthosteric agonist of mGlu₄ by interacting with residues of the glutamate binding pocket of mGlu4, has no activity at other mGlu receptors. Cinnabarinic acid is an endogenous metabolite of the kynurenine pathway of tryptophan. Cinnabarinic acid induces cell apoptosis.

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Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite Related Products (8051)

Antibodies (477)

Endogenous Metabolite Related Products (8051):