2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1278
    D-α-Tocopherol acetate
    		98.32%
    D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine.
    D-α-Tocopherol acetate
  • HY-128965
    N-Glycolylneuraminic acid
    		99.76%
    N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs).
    N-Glycolylneuraminic acid
  • HY-W008638
    2'-Deoxyinosine
    		99.91%
    2’-deoxyadenosine inhibits the growth of human colon-carcinoma cell lines and is found to be associated with purine nucleoside phosphorylase (PNP) deficiency.
    2'-Deoxyinosine
  • HY-113162
    Bovinic acid
    		≥99.0%
    Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities. Bovinic acid is a major constituent of the plant C. lacrima-joby. Bovinic acid possesses insectividal activity against the potato bug and herbicidal activity against wild oat, sun spurge, goosefoot, canary grass, and knotweed.
    Bovinic acid
  • HY-14649G
    Retinoic acid (GMP)
    Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors.
    Retinoic acid (GMP)
  • HY-B0941
    6-Benzylaminopurine
    		99.97%
    6-Benzylaminopurine (Benzyladenine) is the first cytokinin that causes plant growth and development by stimulating cell division and inhibiting respiratory kinases, thereby prolonging the preservation of green vegetables.
    6-Benzylaminopurine
  • HY-14596R
    Genistein (Standard)
    Genistein (Standard) is the analytical standard of Genistein. This product is intended for research and analytical applications. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
    Genistein (Standard)
  • HY-N2325
    D-(+)-Cellobiose
    		99.94%
    D-(+)-Cellobiose is a water-soluble disaccharide and an important intermediate product in the degradation process of cellulose and hemicellulose. D-(+)-cellobiose is used as a carbon source by microorganisms in fermentation processes, where it is converted into ethanol or other metabolic products. D-(+)-Cellobiose has significant application value in biofuel production, such as bioethanol.
    D-(+)-Cellobiose
  • HY-113259
    7α-Hydroxy-4-cholesten-3-one
    		99.60%
    7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1.
    7α-Hydroxy-4-cholesten-3-one
  • HY-W011978
    N-Acetyl-L-tryptophan
    		99.82%
    N-Acetyl-L-tryptophan is an antagonist of the neurokinin-1 receptor (NK-1R), disrupting the binding of substance P (SP) to NK-1R. This action provides neuroprotective effects, improving memory deficits and motor impairments. N-Acetyl-L-tryptophan is also an inhibitor of cytochrome c (Cytochrome c), and it exerts antioxidant and anti-inflammatory effects by inhibiting the expression of IL-1β and the activation of caspase-1. N-Acetyl-L-tryptophan holds promise for research in neurodegenerative and inflammatory diseases.
    N-Acetyl-L-tryptophan
  • HY-101399
    γ-Glu-Phe
    		99.83%
    γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth.
    γ-Glu-Phe
  • HY-B0504S2
    Creatinine-d5
    		99.93%
    Creatinine-d5 is the deuterium labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.
    Creatinine-d<sub>5</sub>
  • HY-113008
    Urocanic acid
    		99.96%
    Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR).
    Urocanic acid
  • HY-113365
    Cholestenone
    		99.81%
    Cholestenone (4-cholesten-3-one) is an orally available antimicrobial agent that is metabolized primarily in the liver as an intermediate oxidation product of cholesterol. Cholestenone inhibits human dermal fibroblast migration and fights Helicobacter pylori infection in vitro and in mouse models by inhibiting cholesterol-α-D-glucopyranoside (CGL). Cholestenone also alleviates metabolic disorders caused by obesity in db/db mice.
    Cholestenone
  • HY-W004282
    Undecanoic acid
    		99.97%
    Undecanoic acid (Undecanoate) is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
    Undecanoic acid
  • HY-N0390S9
    L-Glutamine-15N-1
    		98.0%
    L-Glutamine-15N-1 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
    L-Glutamine-<sup>15</sup>N-1
  • HY-B0389S10
    D-Glucose-13C
    		99.70%
    D-Glucose-13C is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response.
    D-Glucose-<sup>13</sup>C
  • HY-W040307B
    Saccharopine hydrochloride
    		99.84%
    Saccharopine (L-Saccharopine) hydrochloride, a lysine degradation intermediate, is a mitochondrial toxin. Lysine and α-ketoglutarate are converted into Saccharopine hydrochloride by the lysine-ketoglutarate reductase. Saccharopine hydrochloride is then oxidized to α-aminoapidate semialdehyde and glutamate by the saccharopine dehydrogenase. Saccharopine hydrochloride impairs development by disrupting mitochondrial homeostasis.
    Saccharopine hydrochloride
  • HY-N0420S1
    Succinic acid-d4
    		99.0%
    Succinic-2,2,3,3-d4 acid is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
    Succinic acid-d<sub>4</sub>
  • HY-113008B
    trans-Urocanic acid
    		99.84%
    trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function.
    trans-Urocanic acid
Cat. No. Product Name / Synonyms Application Reactivity