2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-125523
    Fumiquinazoline D
    Fumiquinazoline D, a secondary metabolite, is a mycotoxin.
    Fumiquinazoline D
  • HY-N0379S15
    D-mannose-d7
    D-mannose-d7 is the deuterium labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
    D-mannose-d<sub>7</sub>
  • HY-P3026
    Bowman-birk inhibitor
    The Bowman-Birk inhibitor, a highly cross-linked protein featuring seven disulfide bridges, possesses spatially distinct domains specifically designed for the inhibition of both trypsin and chymotrypsin, showcasing its significant role as a plant protease inhibitor with anticarcinogenic properties.
    Bowman-birk inhibitor
  • HY-N0626AR
    Potassium sorbate (Standard)
    Potassium sorbate (Standard) is the analytical standard of Potassium sorbate. This product is intended for research and analytical applications. Potassium sorbate (Sorbic acid potassium) is a highly efficient, and nonpoisonous?food preservatives.?Potassium sorbate generally is an effective inhibitor of most molds and yeasts and some bacteria.
    Potassium sorbate (Standard)
  • HY-B2176S3
    ATP-15N5,d14 dilithium
    ATP-15N5,d14 (Adenosine 5'-triphosphate-15N5,d14) dilithium is deuterium and 15N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
    ATP-<sup>15</sup>N<sub>5</sub>,d<sub>14</sub> dilithium
  • HY-34740S1
    Ethylmalonic acid-d5
    		98.09%
    Ethylmalonic acid-d5 is the deuterium labeled Ethylmalonic acid. Ethylmalonic acid is non-carcinogenic potentially toxic and associated with anorexia nervosa and malonyl-CoA decarboxylase deficiency.
    Ethylmalonic acid-d<sub>5</sub>
  • HY-B0275B
    Oxytetracycline dihydrate
    Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. Oxytetracycline dihydrate potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1 activity.
    Oxytetracycline dihydrate
  • HY-I0626S1
    Cytosine-13C,15N2
    Cytosine-13C,15N2 is the 13C and 15N labeled Cytosine[1]. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[2][3].
    Cytosine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-W018653R
    Cyclohexaneacetic acid (Standard)
    Naloxone (Standard) is the analytical standard of Naloxone. This product is intended for research and analytical applications. Naloxone is an antagonist of Opioid receptor. Naloxone alleviates opioid-overdose-induced respiratory depression. Naloxone may cause pulmonary edema and cardiac arrhythmias.
    Cyclohexaneacetic acid (Standard)
  • HY-135107
    (S)-Ademetionine
    (S)-Ademetionine, also known as S-adenosylmethionine (SAMe), is a widely prevalent metabolite found in all cells and biological fluids, functioning as a key methyl donor in various methylation processes that involve proteins, phospholipids, catecholamines, and DNA.
    (S)-Ademetionine
  • HY-117275A
    Meclofenamic acid sodium hydrate
    Meclofenamic acid (Meclofenamate) sodium hydrate is a non-steroidal anti-inflammatory agent. Meclofenamic acid sodium hydrate is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid sodium hydrate competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid sodium hydrate is a non-selective gap-junction blocker. Meclofenamic acid sodium hydrate inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively.
    Meclofenamic acid sodium hydrate
  • HY-B1092AR
    Gluconate sodium (Standard)
    Gluconate (sodium) (Standard) is the analytical standard of Gluconate (sodium). This product is intended for research and analytical applications. Gluconate sodium (D-Gluconic acid sodium salt) is an orally active glucose derivative. Gluconate sodium reduces nitric oxide and inflammatory cytokines (IL-1β and IL-6). Gluconate sodium inhibits ERK phosphorylation. Gluconate sodium has antioxidant and antiplatelet activation activities. Gluconate sodium has antitumor activity against colorectal cancer. Gluconate sodium improves osteoarthritis, intestinal damage and acute lung injury.
    Gluconate sodium (Standard)
  • HY-16637S2
    (Rac)-Folic acid-13C5,15N
    (Rac)-Folic acid-13C5,15N is the 13C-labeled and 15N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
    (Rac)-Folic acid-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N
  • HY-N10175
    Berkeleyacetal C
    Berkeleyacetal C, a meroterpenoid compound, shows favorable activity of inhibiting nitrogen oxide (NO) production of macrophages stimulated by lipopolysaccharide (LPS). Berkeleyacetal C exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways.
    Berkeleyacetal C
  • HY-169793
    Thalicpureine
    Thalicpureine (compound 12) is a secondary metabolite.
    Thalicpureine
  • HY-N2419R
    Erythrodiol (Standard)
    Erythrodiol (Standard) is the analytical standard of Erythrodiol. This product is intended for research and analytical applications. Erythrodiol is an olive oil component. Erythrodiol promotes Cholesterol efflux (ChE) by selectively inhibiting the degradation of ABCA1 protein. Erythrodiol is a good candidate to be further explored for therapeutic or preventive application in the context of atherosclerosis.
    Erythrodiol (Standard)
  • HY-122211
    MRS2802
    MRS2802 is a P2Y14 receptor agonist with an EC50 value of 63 nM. MRS2802 can effectively activate the P2Y14 receptor and may play a role in regulating platelet function. The selectivity and activity of MRS2802 are conducive to in-depth research on the biological functions and pharmacological properties of P2Y receptors. The development of MRS2802 provides a potential inhibitory strategy for the search for new antiplatelet compounds.
    MRS2802
  • HY-13710
    Dimethindene
    Dimethindene is a potent, selective histamine H1 antagonist. Dimethindene impairs cutaneous wound healing (WH). Dimethindene can block K+ currents.
    Dimethindene
  • HY-W010735R
    ATP (disodium salt hydrate) (Standard)
    ATP (disodium salt hydrate) (Standard) is the analytical standard of ATP (disodium salt hydrate). This product is intended for research and analytical applications. ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation.
    ATP (disodium salt hydrate) (Standard)
  • HY-127038
    Diflumidone sodium
    Diflumidone sodium is a non-steroidal antiinflammatory agent.
    Diflumidone sodium
Cat. No. Product Name / Synonyms Application Reactivity