2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0610AR
    Cinnamic acid (Standard)
    Cinnamic acid (Standard) is the analytical standard of Cinnamic acid. This product is intended for research and analytical applications. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
    Cinnamic acid (Standard)
  • HY-W768347
    Xylitol-13C5
    Xylitol-13C5 (Xylite-13C5) is the 13C-labeled Xylitol (HY-N0538). Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model.
    Xylitol-<sup>13</sup>C<sub>5</sub>
  • HY-W016009S
    2'-Deoxyadenosine-5'-monophosphate-d12 dilithium
    2'-Deoxyadenosine-5'-monophosphate-d12 dilithium is deuterium labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
    2'-Deoxyadenosine-5'-monophosphate-d<sub>12</sub> dilithium
  • HY-13683S2
    Mifepristone-d6
    Mifepristone-d6 is deuterated labeled Mifepristone (HY-13683). Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay.
    Mifepristone-d<sub>6</sub>
  • HY-125863A
    Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant)
    Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) is an NADP-dependent enzyme in the pentose phosphate pathway, which is one of the ways glucose is metabolized. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) can be used to quantify ATP, glucose, and creatine kinase.
    Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant)
  • HY-W751526
    N4-Acetylsulfamethazine-13C6
    N4-Acetylsulfamethazine-13C6 (Sulfamethazine-n4-acetyl-13C6) is the 13C-labeled N4-Acetylsulfamethazine (HY-W290839). N4-Acetylsulfamethazine is a metabolite of Sulfamethazine (HY-B0035). Sulfamethazine is one of the most frequently used sulfonamides in the poultry farming industry.
    N4-Acetylsulfamethazine-<sup>13</sup>C<sub>6</sub>
  • HY-77956S3
    Thyminose-d2
    Thyminose-d2 is the deuterium labeled Thyminose. Thyminose is an endogenous metabolite.
    Thyminose-d<sub>2</sub>
  • HY-113216AS
    Asymmetric dimethylarginine-d7 hydrochloride
    Asymmetric dimethylarginine-d7 (hydrochloride) is the deuterium labeled Asymmetric dimethylarginine hydrochloride.
    Asymmetric dimethylarginine-d<sub>7</sub> hydrochloride
  • HY-N0537S
    Xylose-18O
    Xylose-18O is the 18O labeled Xylose.
    Xylose-<sup>18</sup>O
  • HY-131589R
    Metoprolol acid (Standard)
    Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents.
    Metoprolol acid (Standard)
  • HY-W588264
    3-Iodo-L-thyronine
    3-Iodo-L-thyronine (3-Monoiodothyronine) is a thyroid hormone metabolite. 3-iodo-L-thyronine can bind to apolipoprotein B-100 (apoB-100).
    3-Iodo-L-thyronine
  • HY-165066
    EOS (d18:1/30:0/18:2)
    EOS (d18:1/30:0/18:2) is a kind ceramide in the outer epidermis.
    EOS (d18:1/30:0/18:2)
  • HY-W032013R
    1-Octanol (Standard)
    1-Octanol (Standard) is the analytical standard of 1-Octanol. This product is intended for research and analytical applications. 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties.
    1-Octanol (Standard)
  • HY-113024S
    Pristanic acid-d3
    Pristanic acid-d3 is deuterium labeled Pristanic acid. Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome.
    Pristanic acid-</sub>d<sub>3</sub>
  • HY-P2317A
    Cecropin P1, porcine acetate
    Cecropin P1, porcine acetate is an antibacterial peptide that can be isolated from the upper part of the small intestine of the pig. Cecropin P1, porcine acetate shows antibacterial activity against Gram-negative bacteria. Cecropin P1, porcine acetate shows antiviral activity and inhibits PRRSV infection.
    Cecropin P1, porcine acetate
  • HY-121184
    Epicoccamide
    Epicoccamide, a tetramic acid derivative, is secondary metabolite from Epicoccum purpurascens.
    Epicoccamide
  • HY-113400S1
    Cytidine diphosphate-13C9 dilithium
    Cytidine diphosphate-13C9 dilithium is 13C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
    Cytidine diphosphate-<sup>13</sup>C<sub>9</sub> dilithium
  • HY-128741S
    D-Allose-13C
    D-Allose-13C is the 13C labeled D-Allose (HY-128741). D-Allose exhibits antitumor activity against various cancer cells. D-Allose scavenges reactive oxygen species (ROS) and reduces oxidative stress damage. D-Allose exhibits anti-inflammatory and neuroprotective through inhibition of TLR4/PI3K/AKT signaling pathway. D-Allose exhibits antihypertensive, cryoprotective, and anti-osteoporotic activities.
    D-Allose-<sup>13</sup>C
  • HY-126199S
    (Z)-Tetrachlorvinphos-d6
    (Z)-Tetrachlorvinphos-d6 is the deuterium labeled Tetrachlorvinphos (HY-126199). Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals.
    (Z)-Tetrachlorvinphos-d<sub>6</sub>
  • HY-W012570S
    Decyl aldehyde-d2
    Decyl aldehyde-d2 is deuterated labeled Decyl aldehyde (HY-W012570). Decyl aldehyde is a simple ten-carbon aldehyde. Decyl aldehyde is a bacterial luciferase substrate.
    Decyl aldehyde-d<sub>2</sub>
Cat. No. Product Name / Synonyms Application Reactivity