2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113273
    Ap5A
    Ap5A (Diadenosine pentaphosphate), a diadenosine polyphosphate, is an adenylate kinase inhibitor with a Ki of 2.5 nM. Ap5A can be used for study of cancer.
    Ap5A
  • HY-B1411S1
    i-Inositol-d
    		99.46%
    i-Inositol-d is the deuterium labeled i-Inositol.
    i-Inositol-d
  • HY-145535
    Tetracosanoyl-sulfatide
    Tetracosanoyl-sulfatide is an endogenous metabolite present in Urine that can be used for the research of Mild Metachromatic Leukodystrophy.
    Tetracosanoyl-sulfatide
  • HY-N3686S2
    D-Arabitol-13C-2
    D-Arabitol-13C-2 is the 13C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu.
    D-Arabitol-<sup>13</sup>C-2
  • HY-N10186
    Dibefurin
    Dibefurin is a fungal metabolite that acts as an inhibitor of calcineurin phosphatase.
    Dibefurin
  • HY-113460
    11-trans-Leukotriene C4
    11-trans-Leukotriene C4 is trans-Leukotriene C4 (LTC4). LTC4 is an important inflammatory mediator and regulator of allergic responses.
    11-trans-Leukotriene C4
  • HY-133879
    Calcitriol lactone
    Calcitriol lactone (1α,25-Dihydroxyvitamin D3-26,23-lactone) is a metabolite of vitamin D3. Calcitriol lactone is the active form of vitamin D and affects bone health, cell differentiation, immune function.
    Calcitriol lactone
  • HY-N1480S2
    (-)-Fucose-13C-2
    (-)-Fucose-13C-2 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
    (-)-Fucose-<sup>13</sup>C-2
  • HY-W013061S2
    Propane-1,2,3-triyl tripalmitate-d31
    		≥99.0%
    Propane-1,2,3-triyl tripalmitate-d31 is the deuterium labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
    Propane-1,2,3-triyl tripalmitate-d<sub>31</sub>
  • HY-B0152S2
    Adenine-13C5,15N5
    Adenine-13C5,15C5 (6-Aminopurine-13C5,15C5; Vitamin B4-13C5,15C5) is 13C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
    Adenine-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N<sub>5</sub>
  • HY-W009216S3
    2'-Deoxycytidine-5'-monophosphate-d12 dilithium
    2'-Deoxycytidine-5'-monophosphoric acid-d12 dilithium is deuterium labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
    2'-Deoxycytidine-5'-monophosphate-d<sub>12</sub> dilithium
  • HY-109506R
    DPPC (Standard)
    DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice.
    DPPC (Standard)
  • HY-148197
    Glutathionylspermidine
    Glutathionylspermidine is a peptide and a metabolite of E. coli.
    Glutathionylspermidine
  • HY-W014423R
    L-Histidine hydrochloride hydrate (Standard)
    L-Histidine hydrochloride hydrate (Standard) is the analytical standard of L-Histidine hydrochloride hydrate (HY-W014423). This product is intended for research and analytical applications. L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable.
    L-Histidine hydrochloride hydrate (Standard)
  • HY-W016509R
    epi-Inositol (Standard)
    epi-Inositol (Standard) is the analytical standard of epi-Inositol (HY-W016509). This product is intended for research and analytical applications. epi-Inositol, a inositol analog, is an antidepressant agent. epi-Inositol shows regulatory effects on expression of the most highly regulated gene in the inositol biosynthetic pathway. epi-Inositol shows antiepileptic effect.
    epi-Inositol (Standard)
  • HY-126169
    L-Glutamine amide
    L-Glutamine amide is a metabolite involved in glutamate metabolism.
    L-Glutamine amide
  • HY-128744R
    Phosphonoacetic acid (Standard)
    Phosphonoacetic acid (Standard) is the analytical standard of Phosphonoacetic acid (HY-128744). This product is intended for research and analytical applications. Phosphonoacetic acid is an endogenous metabolite and antiviral agent. Phosphonoacetic acid is active against orthopoxviruses and herpes viruses. Phosphonoacetic acid can inhibit HSV DNA synthesis and virus-specific DNA polymerase activity, and affect the synthesis of late viral proteins.
    Phosphonoacetic acid (Standard)
  • HY-Y1311G
    Malic acid (GMP)
    Malic acid (GMP) is Malic acid (HY-Y1311) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle.
    Malic acid (GMP)
  • HY-70037S
    Cinacalcet-d3
    Cinacalcet-d3 is the deuterium labeled Cinacalcet. Cinacalcet (AMG 073) is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease treatment.
    Cinacalcet-d<sub>3</sub>
  • HY-B0661AS1
    Tamsulosin-d4 hydrochloride
    Tamsulosin-d4 (hydrochloride) is deuterium labeled Tamsulosin (hydrochloride). Tamsulosin hydrochloride ((R)-(-)-YM12617) is an inhibitor of α1-adrenergic receptor. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth in animal models.
    Tamsulosin-d<sub>4</sub> hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity