2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113277R
    3-Methyladipic acid (Standard)
    3-Methyladipic acid (Standard) is the analytical standard of 3-Methyladipic acid. This product is intended for research and analytical applications. 3-Methyladipic acid is the final metabolite in the ω-oxidation pathway.
    3-Methyladipic acid (Standard)
  • HY-133588R
    4-Formylaminoantipyrine (Standard)
    4-Formylaminoantipyrine (Standard) is the analytical standard of 4-Formylaminoantipyrine. This product is intended for research and analytical applications. 4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo.
    4-Formylaminoantipyrine (Standard)
  • HY-W014993S1
    1,3-Dimethyluric acid-dsub>3
    1,3-Dimethyluric acid-d3 is deuterated labeled 1,3-Dimethyluric acid (HY-W014993). 1,3-Dimethyluric acid is a product of theophylline metabolism in man. 1,3-Dimethyluric acid is one of the purine components in urinary calculi.
    1,3-Dimethyluric acid-dsub>3</sub>
  • HY-103164A
    8-(3-Chlorostyryl)caffeine
    8-(3-Chlorostyryl)caffeine (CSC) is an adenosine antagonist with selective activity at the A2a adenosine receptor. 8-(3-Chlorostyryl)caffeine showed 520-fold selectivity in radioligand binding experiments in rat brain. Antagonism of adenylylase by 8-(3-Chlorostyryl)caffeine shows 22-fold selectivity in rat chromaffin cells When 8-(3-Chlorostyryl)caffeine is co-administered with the A1-selective antagonist CPX, It can also further increase exercise activity. 8-(3-Chlorostyryl)caffeine exhibits good MAO-B inhibitory activity in primate mitochondria. 8-(3-Chlorostyryl)caffeine also has excellent A2A receptor affinity.
    8-(3-Chlorostyryl)caffeine
  • HY-E70036
    Galcuronokinase (AtGalAK)
    Galcuronokinase (AtGalAK) is a member of the GHMP kinase family. Galcuronokinase (AtGalAK) catalyzes the ATP-dependent conversion of alpha-d-galacturonic acid (d-GalA) to alpha-d-galacturonic acid-1-phosphate (GalA-1-P).
    Galcuronokinase (AtGalAK)
  • HY-111095S2
    D-(-)-Lactic acid-13C-1
    D-(-)-Lactic acid-13C-1 is the 13C labeled D-(-)-Lactic acid. D-(-)-Lactic acid is a normal intermediate in the fermentation (oxidation, metabolism) of sugar. D-(-)-Lactic acid is identified to be a competitive inhibitor of ProDH (proline dehydrogenase) in plants.
    D-(-)-Lactic acid-<sup>13</sup>C-1
  • HY-W004260S
    Arachidic acid-d2
    Arachidic acid-d2 is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research.
    Arachidic acid-d<sub>2</sub>
  • HY-17461AR
    Cortisone acetate (Standard)
    Cortisone acetate (Standard) is the analytical standard of Cortisone acetate. This product is intended for research and analytical applications. Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations.
    Cortisone acetate (Standard)
  • HY-P2742A
    L-Ascorbate oxidase, Cucumber
    L-Ascorbate oxidase, Cucumber belongs to the family of oxidoreductases acting on diphenols and related substances as donor with oxygen as acceptor. L-Ascorbate oxidase, Cucumber catalyses the oxidation of L‐Ascorbate (HY-B0166) with oxygen to dehydroascorbate with the generation of water. L-Ascorbate oxidase, Cucumber can be used in baking processes and cereal‐based processes.
    L-Ascorbate oxidase, Cucumber
  • HY-I0400S1
    N-Acetylneuraminic acid-13C-1
    N-Acetylneuraminic acid-13C-1 is the 13C labeled N-Acetylneuraminic acid.
    N-Acetylneuraminic acid-<sup>13</sup>C-1
  • HY-W766305
    Thymidine-113C,15N2
    Thymidine-13C,15N2 is the 13C- and 15N-labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.
    Thymidine-1<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-N11948
    Simmondsin
    Simmondsin, derived from the jojoba plant (Simmondsia chinensis), has been shown to decrease food intake and body weight in rats without any noticeable adverse effects.
    Simmondsin
  • HY-N1363R
    Royal Jelly acid (Standard)
    Royal Jelly acid (Standard) is the analytical standard of Royal Jelly acid. This product is intended for research and analytical applications. Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes.
    Royal Jelly acid (Standard)
  • HY-N1393S1
    2-Methoxybenzoic acid-d3
    2-Methoxybenzoic acid-d3 (NSC 3778-d3; O-Methylsalicylic acid-d3; Salicylic acid methyl ether-d3) is deuterium-labeled 2-Methoxybenzoic acid (HY-N1393).
    2-Methoxybenzoic acid-d3
  • HY-125715
    Trigalacturonic acid
    Trigalacturonic acid is an important plant polysaccharide that has the activity of promoting plant cell growth and enhancing cell wall stability. Trigalacturonic acid can improve the ability of plants to adapt to adversity and is widely used as a nutrient in cell culture. Trigalacturonic acid is also used as a food additive with thickening and gelling functions, playing an important role in the food industry.
    Trigalacturonic acid
  • HY-119332
    3-Keto petromyzonol
    3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey.
    3-Keto petromyzonol
  • HY-E70252
    1-Pyrenebutanoyl-CoA
    1-Pyrenebutanoyl-CoA is a type of coenzyme A that can non-competitively inhibit (Ki = 2 μM) phosphorylating (ADP-stimulated) respiration in rat liver mitochondria, and competitively inhibit (Ki = 2.1 μM and 15 μM) carnitine palmitoyl-CoA transferase and octanoyl-CoA transferase.
    1-Pyrenebutanoyl-CoA
  • HY-175394
    β-Hydroxybutyrate methionine
    β-Hydroxybutyrate methionine is a conjugate of β-Hydroxybutyrate and methionine. β-Hydroxybutyrate methionine can be used in obesity research.
    β-Hydroxybutyrate methionine
  • HY-W338294S1
    2'-Deoxycytidine-13C-2 monohydrate
    2'-Deoxycytidine-13C-2 (monohydrate) Monohydrate is the 13C labeled 2'-Deoxycytidine.
    2'-Deoxycytidine-<sup>13</sup>C-2 monohydrate
  • HY-E70043
    Ganglioside sialidase (AuSialidase S)
    Ganglioside sialidase (AuSialidase S) is an endogenous metabolite. Ganglioside sialidases have been implicated in neuronal differentiation processes, including neurite outgrowth.
    Ganglioside sialidase (AuSialidase S)
Cat. No. Product Name / Synonyms Application Reactivity