2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W584173
    D-Glyceric acid calcium hydrate
    D-Glyceric acid calcium hydrate is an endogenous metabolite present in urine that can be used for the research of primary hyperoxaluria type I and glutaric acidemia type 2.
    D-Glyceric acid calcium hydrate
  • HY-P3280A
    γ-Glu-Gly TFA
    γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly TFA has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids.
    γ-Glu-Gly TFA
  • HY-165112
    1,2-Dioleoyl-3-α-linolenoyl-rac-glycerol
    1,2-Dioleoyl-3-α-linolenoyl-rac-glycerol (1,2-Olein-3-α-linolenin) is a compound that is being studied as a triglyceride in bumblebee fat body. Chromatographic analysis revealed differences in fatty acid composition and triglyceride isomer distribution in different bumblebee species.
    1,2-Dioleoyl-3-α-linolenoyl-rac-glycerol
  • HY-125954A
    Uridine diphosphate glucuronic acid ammonium
    Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum.
    Uridine diphosphate glucuronic acid ammonium
  • HY-W874850R
    Fluorodifen (Standard)
    Fluorodifen (Standard) is the analytical standard of Fluorodifen. This product is intended for research and analytical applications. Fluorodifen is a selective herbicide with the activity of inhibiting weed growth. Fluorodifen can effectively control the growth of various annual and perennial broadleaf weeds and some grass weeds, and is widely used in the field management of various crops. By acting on the photosynthesis of plants and the regulation of their growth hormones, Fluorodifen ensures the healthy growth and harvest of crops.
    Fluorodifen (Standard)
  • HY-N0210S5
    D-Galactose-d
    D-Galactose-d is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
    D-Galactose-d
  • HY-103276
    Alytesin
    Alytesin, a bombesin-like peptide, is found in extracts of the skin of Alytes obstetricans. Alytesin reduces gastric acid secretion and induces hypertension. Alytesin also induces short-term anorexigenic effects in neonatal chicks
    Alytesin
  • HY-113259R
    7α-Hydroxy-4-cholesten-3-one (Standard)
    7α-Hydroxy-4-cholesten-3-one (Standard) is the analytical standard of 7α-Hydroxy-4-cholesten-3-one. This product is intended for research and analytical applications. 7α-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7α-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7α-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7α-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1.
    7α-Hydroxy-4-cholesten-3-one (Standard)
  • HY-W012999R
    Tiglic acid (Standard)
    Tiglic acid (Standard) is the analytical standard of Tiglic acid. This product is intended for research and analytical applications. Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite[1].
    Tiglic acid (Standard)
  • HY-I0960S7
    Uracil-d1
    Uracil-d1 is the deuterium labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.
    Uracil-d<sub>1</sub>
  • HY-W040047S
    Pregnanediol 3-glucuronide-13C5
    Pregnanediol 3-glucuronide-13C5 is 13C-labeled Pregnanediol (HY-107850) Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo.
    Pregnanediol 3-glucuronide-<sup>13</sup>C<sub>5</sub>
  • HY-N7092S14
    D-Fructose-d-2
    D-Fructose-d-2 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
    D-Fructose-d-2
  • HY-111094
    NPD7155
    NPD7155 is a purine-based competitive inhibitor of MTH1, designed to target cancer cells while exhibiting off-target effects that contribute to its cytotoxicity.
    NPD7155
  • HY-146567S
    meso-Erythritol-d6
    meso-Erythritol-d6 is the deuterium labeled meso-Erythritol (HY-100551). meso-Erythritol is a sugar alcohol that found in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and can be used as low-calorie sweetener food additives.
    meso-Erythritol-d<sub>6</sub>
  • HY-B1674S4
    (±)-Leucine-d7
    (±)-Leucine-d7 is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%.
    (±)-Leucine-d<sub>7</sub>
  • HY-N0001S
    (±)-Epicatechin-13C3
    (±)-Epicatechin-13C3 is the 13C labeled (±)-Epicatechin. (-)-Epicatechin (HY-N0001) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
    (±)-Epicatechin-<sup>13</sup>C<sub>3</sub>
  • HY-115371
    Butaperazine dimaleate
    Butaperazine dimaleate is an antipsychotic compound with activity for the detection of vanadium (V). Butaperazine dimaleate can react with vanadium (V) in a phosphoric acid medium to form a red radical cation. The absorption spectrum of butaperazine dimaleate reaches a maximum at 513 nm, which conforms to Beer's law and corresponds to a concentration range of 0.25-5.0 μg/ml. Butaperazine dimaleate has a sensitivity value of 6.1 ng/cm2 and is suitable for the analysis of vanadium steel, minerals, biological samples, and soil samples.
    Butaperazine dimaleate
  • HY-N0230R
    β-Alanine (Standard)
    β-Alanine (Standard) is the analytical standard of β-Alanine. This product is intended for research and analytical applications. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
    β-Alanine (Standard)
  • HY-B0234S
    Estrone-13C3
    		98.0%
    Estrone-13C3 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells.
    Estrone-<sup>13</sup>C<sub>3</sub>
  • HY-113277R
    3-Methyladipic acid (Standard)
    3-Methyladipic acid (Standard) is the analytical standard of 3-Methyladipic acid. This product is intended for research and analytical applications. 3-Methyladipic acid is the final metabolite in the ω-oxidation pathway.
    3-Methyladipic acid (Standard)
Cat. No. Product Name / Synonyms Application Reactivity