2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W654004
    8-Hydroxy guanosine-13C,15N2
    8-Hydroxy guanosine-13C,15N2 is 13C and 15N labeled 8-Hydroxyguanosine. 8-Hydroxyguanosine, an oxidized nucleoside, is a marker of RNA oxidative damage and oxidative stress. 8-Hydroxyguanosine stimulates proliferation and differentiation of B cells.
    8-Hydroxy guanosine-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-W001179R
    2,5-Dihydroxybenzoic acid (Standard)
    2,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of fibroblast growth factors.
    2,5-Dihydroxybenzoic acid (Standard)
  • HY-113013A
    Hydroxypyruvic acid lithium hydrate
    Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.
    Hydroxypyruvic acid lithium hydrate
  • HY-B0131S2
    Prostaglandin E1-d9
    Prostaglandin E1-d9 is deuterium labeled Prostaglandin E1.Prostaglandin E1 is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inh
    Prostaglandin E1-d<sub>9</sub>
  • HY-N0379S5
    D-Mannose-13C
    		99.90%
    D-Mannose-13C is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote.
    D-Mannose-<sup>13</sup>C
  • HY-W001132S2
    Indole-13C8,15N
    Indole-13C8,15N is the 13C and 15N labeled Indole. Indole is an endogenous metabolite.
    Indole-<sup>13</sup>C<sub>8</sub>,<sup>15</sup>N
  • HY-117463
    Dexamethasone beloxil
    Dexamethasone beloxil (AL-2512) is a novel corticosteroid with anti-inflammatory and ocular hypertensive effects .
    Dexamethasone beloxil
  • HY-B0910AR
    Pyrithioxin dihydrochloride (Standard)
    Pyrithioxin (dihydrochloride) (Standard) is the analytical standard of Pyrithioxin (dihydrochloride). This product is intended for research and analytical applications.
    Pyrithioxin dihydrochloride (Standard)
  • HY-N10257
    Burnettramic acid A aglycone
    Burnettramic acid A aglycone is a fungal metabolite found in Aspergillus burnettii.
    Burnettramic acid A aglycone
  • HY-113027R
    p-Hydroxymandelic acid (Standard)
    Melatonin (Standard) is the analytical standard of Melatonin. This product is intended for research and analytical applications. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress.
    p-Hydroxymandelic acid (Standard)
  • HY-113420S2
    11-Dehydro-thromboxane B2-13C5
    11-Dehydro-thromboxane B2-13C5 is 13C labeled 11-Dehydro-thromboxane B2 (HY-113420). 11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis.
    11-Dehydro-thromboxane B2-<sup>13</sup>C<sub>5</sub>
  • HY-113208A
    11β-13,14-Dihydro-15-keto Prostaglandin F2α
    11β-13,14-Dihydro-15-keto Prostaglandin F2α is the deviative of 13,14-Dihydro-15-keto PGF2a (HY-113208), which is an endogenous metabolite present in Blood that can be used for the research of Pregnancy.
    11β-13,14-Dihydro-15-keto Prostaglandin F2α
  • HY-P4290
    Antiulcer Agent 2
    Antiulcer Agent 2 is a tetrapeptide containing aspartic acid, alanine, histidine, and lysine. Antiulcer Agent 2 is present at the N-terminal of human albumin. Antiulcer Agent 2 has potential applications in ulcers and active oxygen generation.
    Antiulcer Agent 2
  • HY-W096561
    Amiquinsin
    Amiquinsin is a compound with hypotensive activity. Amiquinsin is metabolized in vivo, and the major metabolite is 4-amino-6,7-dimethoxy-3-quinolinol hydrochloride hydrate. The pharmacological and toxicological properties of amiquinsin have been widely discussed.
    Amiquinsin
  • HY-116765
    MAO-B-IN-35
    MAO-B-IN-35 is a potent, selective, reversible monoamine oxidase B (MAO-B) inhibitor with high inhibitory activity. MAO-B-IN-35 can exhibit high selectivity and potency at a small molecule scale. MAO-B-IN-35 is designed and synthesized so that it can be efficiently obtained during standard synthesis procedures and has superior physical and chemical properties.
    MAO-B-IN-35
  • HY-B0399G
    L-Carnitine (GMP)
    L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism.
    L-Carnitine (GMP)
  • HY-W014423S8
    L-Histidine-15N3,d5 hydrochloride hydrate
    L-Histidine-15N3,d5 hydrochloride hydrate is the deuterium and 15N labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable.
    L-Histidine-<sup>15</sup>N<sub>3</sub>,d<sub>5</sub> hydrochloride hydrate
  • HY-P2856
    Phosphatidylinositol phosphodiesterase
    Phosphatidylinositol phosphodiesterase hydrolyzes phosphatidylinositol to diacylglycerols and a mixture of myoinositol 1- and 1, 2-cyclic phosphates.
    Phosphatidylinositol phosphodiesterase
  • HY-77956S2
    Thyminose-13C-2
    Thyminose-13C-2 is the 13C labeled Thyminose. Thyminose is an endogenous metabolite.
    Thyminose-<sup>13</sup>C-2
  • HY-113144R
    L-Hexanoylcarnitine (Standard)
    L-Hexanoylcarnitine (Standard) is the analytical standard of L-Hexanoylcarnitine. This product is intended for research and analytical applications. L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease.
    L-Hexanoylcarnitine (Standard)
Cat. No. Product Name / Synonyms Application Reactivity