2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-101480A
    Xylamidine tosylate
    Xylamidine tosylate is a serotonin inhibitor with reproductive activity. Xylamidine tosylate can affect reproductive processes and may be used as an experimental tool in related research. The mechanism of action of Xylamidine tosylate involves the regulation of the serotonin system.
    Xylamidine tosylate
  • HY-E70256
    12:0 Coenzyme A triammonium
    12:0 Coenzyme A (Lauroyl coenzyme A triammonium) is an intermediary in fatty acid synthesis or metabolism, formed by combining long-chain fatty acids (or lauric acid) with coenzyme A. 12:0 Coenzyme A is involved in lipid biosynthesis and fatty acid transport, in which coenzyme A acts as a transport molecule to help move and target specific compounds.
    12:0 Coenzyme A triammonium
  • HY-E70324
    Amoxicillin acylase (Immobilized)
    Amoxicillin acylase (Immobilized) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible.
    Amoxicillin acylase (Immobilized)
  • HY-P2588
    Osteocalcin (human)
    Osteocalcin (human) is a vitamin K-dependent bone specific protein. Osteocalcin (human) is chemotactic for several of the cell types frequently found at bone remodeling surfaces.
    Osteocalcin (human)
  • HY-W749641
    (7Z,9E)-Dodecadienyl acetate
    (7Z,9E)-Dodecadienyl acetate is a female pheromone isolated from female grapevine moths.
    (7Z,9E)-Dodecadienyl acetate
  • HY-W768246
    Galactose 1-phosphate-13C6 potassium
    Galactose 1-phosphate-13C6 potassium is the 13C-labeled Galactose 1-phosphate Potassium salt (HY-113143A). Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sugars.
    Galactose 1-phosphate-<sup>13</sup>C<sub>6</sub> potassium
  • HY-W768333
    D-Ribofuranose-13C5
    D-Ribofuranose-13C5 (D-Ribose-13C5) is the 13C-labeled D-Ribofuranose (HY-113375). D-Ribofuranose (D-Ribose) is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency and Medium Chain Acyl Co A Dehydrogenase Deficiency.
    D-Ribofuranose-<sup>13</sup>C<sub>5</sub>
  • HY-W004260B
    Dieicosanoin
    Dieicosanoin is a diacylglycerol containing arachidic acid (HY-W004260). Arachidic acid is a saturated long-chain fatty acid with a 20-carbon backbone. Arachidic acid can be isolated from peanut butter and anaerobic fungi.
    Dieicosanoin
  • HY-N10228
    Gliorosein
    Gliorosein is a fungal metabolite isolated from Gliocladium. Gliorosein is isomeric with the quinol but shows a different ultraviolet absorption spectrum.
    Gliorosein
  • HY-B0400S7
    D-Sorbitol-d-2
    D-Sorbitol-d-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
    D-Sorbitol-d-2
  • HY-N7718
    (−)-Rugulosin
    (−)-Rugulosin is a fungal metabolite and an orally active anti-influenzal agent.
    (−)-Rugulosin
  • HY-129099
    N-Desmethyltamoxifen
    N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
    N-Desmethyltamoxifen
  • HY-N0667S1
    L-Asparagine-15N2,d8
    L-Asparagine-15N2,d8 is the 15N- and deuterium labeled L-Asparagine (HY-N0667). L-Asparagine is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine-<sup>15</sup>N<sub>2</sub>,d<sub>8</sub>
  • HY-W674036
    11-Mercaptoundecylphosphoric acid
    11-Mercaptoundecylphosphoric acid is a phosphate compound with good biocompatibility and anti-cell adhesion activity. 11-Mercaptoundecylphosphoric acid can be used to construct surface modification of biomaterials and improve its application potential in the biomedical field. By adjusting its concentration and application method, 11-Mercaptoundecylphosphoric acid can effectively control the behavior and function of cells.
    11-Mercaptoundecylphosphoric acid
  • HY-129824
    3-Methyl orsellinic acid
    3-Methyl orsellinic acid is the fungal metabolite. 3-Methyl orsellinic acid can be used for synthesis of tripodalsporormielones AeC, and exhibits potential in researches related to memory and cognition.
    3-Methyl orsellinic acid
  • HY-W750959
    L-Methionine sulfoxide-13C
    L-Methionine sulfoxide-13C (H-Met(O)-OH-13C) is the 13C-labeled L-Methionine sulfoxide (HY-W010104). L-Methionine sulfoxide is an orally active oxidation product of Methionine (HY-N0326). L-Methionine sulfoxide can be partially converted into Methionine in the body and participate in the synthesis of glutathione in the liver. L-Methionine sulfoxide provides the body with sulfur activity and can participate in the synthesis of proteins and sulfur-containing compounds.
    L-Methionine sulfoxide-<sup>13</sup>C
  • HY-114930
    Endopeptidase-IN-1
    Endopeptidase-IN-1 serves as an inhibitor of endopeptidase activity.
    Endopeptidase-IN-1
  • HY-W010104AR
    Methionine sulfoxide (Standard)
    Methionine sulfoxide (Standard) is the analytical standard of Methionine sulfoxide. This product is intended for research and analytical applications. Methionine sulfoxide is an oxidation product of methionine with reactive oxygen species and can be regarded as a biomarker of oxidative stress in vivo.
    Methionine sulfoxide (Standard)
  • HY-W714691
    Coproporphyrin III-15N4
    Coproporphyrin III-15N4 (Zincphyrin-15N4) is the 15N-labeled Coproporphyrin III (HY-101398). Coproporphyrin III (Zincphyrin) is a naturally occurring porphyrin derivative that is mainly found in urine.
    Coproporphyrin III-<sup>15</sup>N<sub>4</sub>
  • HY-B0456S1
    Riboflavin-5-Phosphate-13C4,15N2-1
    Riboflavin-5-Phosphate-13C4,15N2-1 is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
    Riboflavin-5-Phosphate-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>2</sub>-1
Cat. No. Product Name / Synonyms Application Reactivity