2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-125344
    Fusarisetin A
    Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor.
    Fusarisetin A
  • HY-22385B
    (S)-Salsolidine
    (S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (Ki=63 μM). The R enantiomer of Salsolidine is more potent than the S form (Ki=26 μM).
    (S)-Salsolidine
  • HY-N0132R
    Synephrine (Standard)
    Synephrine (Standard) is the analytical standard of Synephrine. This product is intended for research and analytical applications. Synephrine (Oxedrine), an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine is a sympathomimetic compound and can be used for weight loss.
    Synephrine (Standard)
  • HY-118079
    Drimentine B
    Drimentine B is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria that has anticancer activity. It inhibits the proliferation of NS-1 murine β lymphocyte myeloma cells by 41 and 59% in vitro when used at concentrations of 50 and 100 μg/mL, respectively.
    Drimentine B
  • HY-142976
    Tetranor-12(S)-HETE
    Tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE (HY-124404A) in numerous tissues. 12(S)‐HETE to tetranor‐12(S)‐HETE conversion could be a marker for psoriasis.
    Tetranor-12(S)-HETE
  • HY-111355
    Cholesterol sulfate
    Cholesterol sulfate is a DOCK2 inhibitor. Cholesterol sulfate has an IC50 value of 2 μM for mouse DOCK2. Cholesterol sulfate can be used in studies such as immunity and inflammation.
    Cholesterol sulfate
  • HY-E70615
    Protein Disulfide Isomerase, Human
    Protein Disulfide Isomerase, Human, an oxidoreductase, is a mainly endoplasmic reticulum (ER) resident protein. Protein Disulfide Isomerase, Human plays an important role in maintaining cellular homeostasis through thiol oxidation/reduction cycling, chaperone action, and isomerization of client proteins.
    Protein Disulfide Isomerase, Human
  • HY-W750719
    Neurosporene
    Neurosporene is a carotenoid. Neurosporene is an intermediate in the synthesis of Lycopene (HY-N0287). Neurosporene can be isolated from date palm, Kocuria sp. GMA bacteria, and Anthurus archeri fungi. Neurosporene has antioxidant activity. Neurosporene can be used in the research of diseases such as cancer.
    Neurosporene
  • HY-N6787S
    5,6-Dihydro-5-methyluracil-d6
    5,6-Dihydro-5-methyluracil-d6 is the deuterium labeled 5,6-Dihydro-5-methyluracil. 5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels.
    5,6-Dihydro-5-methyluracil-d<sub>6</sub>
  • HY-16516R
    Vitamin CK3 (Standard)
    Vitamin CK3 (Standard) is the analytical standard of Vitamin CK3. This product is intended for research and analytical applications. Vitamin CK3 is the combination of Vitamin C and vitamin K3 (100:1 ratio) and has been shown to inhibit tumor growth and lung metastasis.
    Vitamin CK3 (Standard)
  • HY-145533A
    3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid sodium
    3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) sodium is a sialic acid. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid sodium protects the oligo/(poly)sialyl chains from exosialidases at nonreducing terminal, and plays a role in egg activation of salmonid fish. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid sodium is abundant in fetal cord red blood cells and malignant human ovarian cancer cells.
    3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid sodium
  • HY-N0142R
    Phloretin (Standard)
    Phloretin (Standard) is the analytical standard of Phloretin. This product is intended for research and analytical applications. Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill., has anti-inflammatory activities. Phloridzin is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). Phloretin inhibits Yeast-made GLUT1 as well as Human erythrocyte GLUT1 with IC50values of 49 μM and 61 μM, respectively.Phloretin has the potential for the treatment of rheumatoid arthritis (RA) and allergic airway inflammation.
    Phloretin (Standard)
  • HY-13417S
    AICAR-13C2,15N
    AICAR-13C2,15N (Acadesine-13C2,15N; AICA Riboside-13C2,15N) is the 13C and 15N labeled AICAR (HY-13417). AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor.
    AICAR-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N
  • HY-N3686S1
    D-Arabitol-13C-1
    D-Arabitol-13C-1 is the 13C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu.
    D-Arabitol-<sup>13</sup>C-1
  • HY-171941A
    C24:1 Ganglioside GM1 (d18:1/24:1) ammonium
    C24:1 Ganglioside GM1 (d18:1/24:1) (ammonium) is a monosialylated ganglioside that contains nervonic acid.
    C24:1 Ganglioside GM1 (d18:1/24:1) ammonium
  • HY-E70010
    Aldose 1-epimerase
    Aldose 1-epimerase (mutarotases) is a key enzyme of carbohydrate metabolism catalysing the interconversion of the α- and β-anomers of hexose sugars such as glucose and galactose. Aldose 1-epimerase is essential for normal carbohydrate metabolism and the production of complex oligosaccharides.
    Aldose 1-epimerase
  • HY-N0537S12
    Xylose-d-3
    Xylose-d-3 is the deuterium labeled Xylose.
    Xylose-d-3
  • HY-139231
    1-Palmitoyl-2-formylyl PC
    1-Palmitoyl-2-formylyl PC (PFPC) is a formate-containing PC lipid.
    1-Palmitoyl-2-formylyl PC
  • HY-118915
    FR 106969
    FR 106969 (A26771E) is a platelet activating factor antagonist with anti-inflammatory activity. FR 106969 can be used to alleviate inflammatory responses. FR 106969 has shown potential inhibitory effects on inflammation-related diseases in studies.
    FR 106969
  • HY-Y0921S
    (±)-1,2-Propanediol-d8
    		99.55%
    (±)-1,2-Propanediol-d8 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents.
    (±)-1,2-Propanediol-d<sub>8</sub>
Cat. No. Product Name / Synonyms Application Reactivity