2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0216S2
    Ethynyl Estradiol-13C2
    Ethynyl Estradiol-13C2 is the 13C-labeled Ethynyl Estradiol. Ethynyl Estradiol-13C2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ethynyl Estradiol-<sup>13</sup>C<sub>2</sub>
  • HY-130550
    (±)7(8)-EpDPA
    (±)7(8)-EpDPA is an epoxide derivative of docosahexaenoic acid (DHA) metabolized by CYP450.
    (±)7(8)-EpDPA
  • HY-Z0792S
    4-O-Methyldopa-d3
    4-O-Methyldopa-d3 is deuterium labeled 4-O-Methyldopamine.
    4-O-Methyldopa-d<sub>3</sub>
  • HY-B1500R
    2,2,2-Trichloroethanol (Standard)
    2,2,2-Trichloroethanol (Standard) is the analytical standard of 2,2,2-Trichloroethanol. This product is intended for research and analytical applications. 2,2,2-Trichloroethanol, the active form of Chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4).
    2,2,2-Trichloroethanol (Standard)
  • HY-128738R
    Thymidine-5'-monophosphate disodium salt (Standard)
    Thymidine-5'-monophosphate (disodium) salt (Standard) is the analytical standard of Thymidine-5'-monophosphate (disodium) salt. This product is intended for research and analytical applications. Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.
    Thymidine-5'-monophosphate disodium salt (Standard)
  • HY-N6612S
    D-Glucuronic acid sodium monohydrate-13C6
    D-Glucuronic acid sodium monohydrate-13C6 is the 13C-labeled D-Glucuronic acid sodium salt monohydrate (HY-N6612A). D-Glucuronic acid sodium salt monohydrate is an endogenous metabolite.
    D-Glucuronic acid sodium monohydrate-<sup>13</sup>C<sub>6</sub>
  • HY-W009444S4
    5-Methyluridine-5′-13C
    5-Methyluridine-5′-13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu.
    5-Methyluridine-5′-<sup>13</sup>C
  • HY-147406A
    Tonlamarsen sodium
    		Inhibitor
    Tonlamarsen sodium is a angiotensinogen synthesis reducer, with antihypertensive activity.
    Tonlamarsen sodium
  • HY-W483854
    N-Formyl-2-aminophenol
    N-Formyl-2-aminophenol (N-(2-hydroxyphenyl)methanamide) is a bacterial secondary metabolite that has been found in P. chrysogenum and has antioxidant activity.
    N-Formyl-2-aminophenol
  • HY-N11200R
    3-Hydroxyisovalerylcarnitine (Standard)
    3-Hydroxyisovalerylcarnitine (Standard) is the analytical standard of 3-Hydroxyisovalerylcarnitine. This product is intended for research and analytical applications. 3-Hydroxyisovalerylcarnitine is a carnitine derivative. 3-Hydroxyisovaleryl carnitine in plasma may serve as a novel biomarker of biotin deficiency in humans, with its concentration increasing with biotin deficiency. Biotin deficiency reduces the activity of biotin-dependent 3-methylcrotonyl-CoA carboxylase, hinders the conversion of 3-methylcrotonyl-CoA into 3-methylglutaconyl-CoA, and impairs the leucine catabolism pathway; resulting in plasma 3-Hydroxyisovalerylcarnitine concentrations rise.
    3-Hydroxyisovalerylcarnitine (Standard)
  • HY-W004283S2
    Pentadecanoic acid-d2
    Pentadecanoic acid-d2 is the deuterium labeled Pentadecanoic acid. Pentadecylic acid is a saturated fatty acid with a 15-carbon backbone.
    Pentadecanoic acid-d<sub>2</sub>
  • HY-130440
    Leukotriene F4
    Leukotriene F4 (LTF4), is a lipid that belongs to the Cysteinyl Leukotriene (CysTL) family. Leukotriene F4 induces bronchoconstriction with an ED50 of 16 μg/kg. The precursor of LTF4 is Leukotriene E4 (LTE4), which isformed from the action of a glutamyl transferase.
    Leukotriene F4
  • HY-N2334R
    Glycochenodeoxycholic acid (Standard)
    		Inducer
    Glycochenodeoxycholic acid (Standard) is the analytical standard of Glycochenodeoxycholic acid. This product is intended for research and analytical applications. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC)[1][2][3][4].
    Glycochenodeoxycholic acid (Standard)
  • HY-N10197
    Pulixin
    Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.
    Pulixin
  • HY-106950CS
    Fosfructose-1-13C sodium
    Fosfructose-1-13C (sodium) is the 13C labeled Fosfructose.
    Fosfructose-1-<sup>13</sup>C sodium
  • HY-113209A
    ent-8-Iso-15(S)-prostaglandin F2α
    Ent-8-Iso-15(S)-prostaglandin F2α is an isomer of 8-Isoprostaglandin F2α, with a better inhibiting activity in the whole blood platelet aggregation inhibition assay.
    ent-8-Iso-15(S)-prostaglandin F2α
  • HY-P2753
    Sucrose phosphorylase
    Sucrose phosphorylase is a bacterial transglucosidase that catalyzes the conversion of sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose. The glucosylated Sucrose phosphorylase can also be hydrolyzed into α-D-glucose, or transfer the glucoyl to the hydroxyl group of the receptor, and then decomposed into new α-D-glucoside products. The enzymatic activity of base phosphorylase to substrate and product is weak.
    Sucrose phosphorylase
  • HY-121883R
    Lignoceric acid (Standard)
    Lignoceric acid (Standard) is the analytical standard of Lignoceric acid. This product is intended for research and analytical applications. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].
    Lignoceric acid (Standard)
  • HY-B2220B
    Thermostable cellulase (recombinant)
    Thermostable cellulase (recombinant) is a heat-stable cellulose enzyme expressed in hyperthermophilic bacteria. Thermostable cellulase (recombinant) can hydrolyze cellulose biomass into fermentable sugars at high temperatures, which can be used for biofuel production.
    Thermostable cellulase (recombinant)
  • HY-Y1422C
    Lipase, Chromobacterium viscosum
    Lipase, Chromobacterium viscosum catalyzes the hydrolysis of ester bonds in lipids into glycerol and fatty acids. Lipase, Chromobacterium viscosum is involved in the digestion of fats and can be used industrially for the production of flavors, pharmaceuticals, and biodiesel.
    Lipase, Chromobacterium viscosum
Cat. No. Product Name / Synonyms Application Reactivity