2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0680R
    Thiamine hydrochloride (Standard)
    Thiamine (hydrochloride) (Standard) is the analytical standard of Thiamine (hydrochloride). This product is intended for research and analytical applications. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine hydrochloride (Standard)
  • HY-113121S1
    Vanillylmandelic acid-d
    Vanillylmandelic acid-d is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM.
    Vanillylmandelic acid-d
  • HY-N0486S11
    L-Leucine-d
    L-Leucine-d is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
    L-Leucine-d
  • HY-N1429S2
    Taurochenodeoxycholic acid-d4-1 sodium
    Taurochenodeoxycholic acid-d4-1 (sodium) is the deuterium labeled Taurochenodeoxycholic acid. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties.
    Taurochenodeoxycholic acid-d<sub>4</sub>-1 sodium
  • HY-129554R
    cis-9,10-Epoxystearic acid (Standard)
    cis-​9,​10-​Epoxystearic acid (Standard) (cis-9,10-Epoxyoctadecanoic acid (Standard)) is the analytical standard of cis-​9,​10-​Epoxystearic acid (HY-129554). This product is intended for research and analytical applications. cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) is an endogenous metabolite that can be found in plasma and urine.
    cis-9,10-Epoxystearic acid (Standard)
  • HY-18569AR
    3-Indoleacetic acid sodium (Standard)
    Ginsenoside F1 (Standard) is the analytical standard of Ginsenoside F1. This product is intended for research and analytical applications. Ginsenoside F1, an enzymatically modified derivative of Ginsenoside Rg1, demonstrates competitive inhibition of CYP3A4 activity and weaker inhibition of CYP2D6 activity.
    3-Indoleacetic acid sodium (Standard)
  • HY-W008940R
    Cytidine 5'-diphosphate disodium salt (Standard)
    Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
    Cytidine 5'-diphosphate disodium salt (Standard)
  • HY-N10475
    4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone
    4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone (compound 3) is a hydroxylated microbial metabolite of Yangonin.
    4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone
  • HY-101403R
    N-(5-Aminopentyl)acetamide (Standard)
    N-(5-Aminopentyl)acetamide (Standard) is the analytical standard of N-(5-Aminopentyl)acetamide. This product is intended for research and analytical applications. N-(5-Aminopentyl)acetamide is the acetylated form of the polyamine cadaverine.
    N-(5-Aminopentyl)acetamide (Standard)
  • HY-116825
    Jalapinolic acid
    Jalapinolic acid (11-Hydroxyhexadecanoic acid; 11-Hydroxypalmitic acid) is a hydroxyhexadecanoic acid.
    Jalapinolic acid
  • HY-Y0921S3
    (±)-1,2-Propanediol-13C3
    (±)-1,2-Propanediol-13C3 is 13C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish.
    (±)-1,2-Propanediol-<sup>13</sup>C<sub>3</sub>
  • HY-136341R
    7,8-Dihydroneopterin (Standard)
    Sanguinarine (Standard) is the analytical standard of Sanguinarine. This product is intended for research and analytical applications. Sanguinarine (Sanguinarin), a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
    7,8-Dihydroneopterin (Standard)
  • HY-113105
    Estriol 16α-(β-D-glucuronide)
    Estriol 16α-(β-D-glucuronide) is an endogenous metabolite present in Urine that can be used for the research of Pregnancy.
    Estriol 16α-(β-D-glucuronide)
  • HY-D0184S5
    2'-Deoxycytidine-13C9
    2'-Deoxycytidine-13C9 (Deoxycytidine-13C9; Cytosine deoxyriboside-13C9; Deoxyribose cytidine-13C9) is 13C-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
    2'-Deoxycytidine-<sup>13</sup>C<sub>9</sub>
  • HY-N1798
    Quercetin 3,7-dimethyl ether
    Quercetin 3,7-dimethyl ether, isolated from Croton schiedeanus Schlecht, has a NO/cGMP pathway-related profile, with increased vasorelaxant activity.
    Quercetin 3,7-dimethyl ether
  • HY-E70304
    Mannosyl-oligosaccharide 1,2-α-mannosidase IA
    Mannosyl-oligosaccharide 1,2-α-mannosidase IA (MAN1A1) is a glycosidase that catalyzes the hydrolysis of α-1,2-linked mannose residues in Man(9)GlcNAc(2) to produce Man(9)GlcNAc(2).
    Mannosyl-oligosaccharide 1,2-α-mannosidase IA
  • HY-113252S1
    2-Methoxyestrone-13C6
    2-Methoxyestrone-13C6 is the 13C-labeled 2-Methoxyestrone. 2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81.
    2-Methoxyestrone-<sup>13</sup>C<sub>6</sub>
  • HY-B0154S1
    Fluticasone propionate-d5
    Fluticasone propionate-d5 is deuterium labeled Fluticasone (propionate). Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity.
    Fluticasone propionate-d<sub>5</sub>
  • HY-E70019
    alpha-2-3,6-sialidase (BiNanH2)
    alpha-2-3,6-sialidase (BiNanH2) is a sialyltransferase, is often used in biochemical studies. alpha-2-3,6-sialidase (BiNanH2) catalyzes α-2,3/2,6-sialyltransfer from CMP-Neu5Ac to galactoside acceptors.
    alpha-2-3,6-sialidase (BiNanH2)
  • HY-W010918S3
    Adenosine 5'-diphosphate-13C5
    Adenosine 5'-diphosphate-13C5 (Adenosine diphosphate-13C5) is the 13C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors.
    Adenosine 5'-diphosphate-<sup>13</sup>C<sub>5</sub>
Cat. No. Product Name / Synonyms Application Reactivity