2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-123033
    Nicotinamide riboside
    Nicotinamide riboside, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.
    Nicotinamide riboside
  • HY-113365S1
    Cholestenone-13C
    		≥99.0%
    Cholestenone-13C is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells.
    Cholestenone-<sup>13</sup>C
  • HY-145731
    Fructose-leucine
    		99.89%
    Fructose-leucine (Fru-Leu) is an Amadori compound that can be found in tobacco and is a precursor of aroma formed during the early stages of the Maillard reaction.
    Fructose-leucine
  • HY-W011175
    Batilol
    		≥98.0%
    3-(Octadecyloxy)propane-1,2-diol is an endogenous metabolite.
    Batilol
  • HY-D0885D
    Phosphocreatine disodium hydrate
    		99.57%
    Phosphocreatine (disodium hydrate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium hydrate) enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine (disodium hydrate) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium hydrate) Phosphocreatine (disodium hydrate) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway..
    Phosphocreatine disodium hydrate
  • HY-N8357
    Vitamin D3 octanoate
    Vitamin D3 octanoate is an octanoate ester of vitamin D3. Vitamin D3 (Cholecalciferol; HY-15398) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
    Vitamin D3 octanoate
  • HY-113408R
    Tiglyl carnitine (Standard)
    Tiglyl carnitine (Standard) is the analytical standard of Tiglyl carnitine. This product is intended for research and analytical applications. Tiglyl carnitine is found to be associated with celiac disease and mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.
    Tiglyl carnitine (Standard)
  • HY-50723R
    3-Methylxanthine (Standard)
    3-Methylxanthine (Standard) is the analytical standard of 3-Methylxanthine. This product is intended for research and analytical applications. 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.
    3-Methylxanthine (Standard)
  • HY-158292
    Digoxin-OVA
    Digoxin-OVA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Digoxin-OVA
  • HY-W015967R
    Glycolic acid (Standard)
    Glycolic acid (Standard) is the analytical standard of Glycolic acid. This product is intended for research and analytical applications. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
    Glycolic acid (Standard)
  • HY-W009216S
    2'-Deoxycytidine-5'-monophosphate-15N3
    		98.76%
    2'-Deoxycytidine-5'-monophosphoric acid-15N3 is the 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid. 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
    2'-Deoxycytidine-5'-monophosphate-<sup>15</sup>N<sub>3</sub>
  • HY-W068783
    (E)-3,4-(Methylenedioxy)cinnamic acid
    		99.87%
    (E)-3,4-(Methylenedioxy)cinnamic acid is a cinnamic acid derivative obtained from the stem bark of Brombya platynema.
    (E)-3,4-(Methylenedioxy)cinnamic acid
  • HY-125770
    5(S)​-​HPETE
    		≥98.0%
    5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs.
    5(S)​-​HPETE
  • HY-W077257
    5-Bromo-DL-tryptophan
    		99.89%
    5-Bromo-DL-tryptophan is a natural product which can be obtained from Aspergillus fumigatus.
    5-Bromo-DL-tryptophan
  • HY-W012980S1
    Isovaleric acid-13C
    		99.0%
    Isovaleric acid-13C is the 13C labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.
    Isovaleric acid-<sup>13</sup>C
  • HY-17583R
    Griseofulvin (Standard)
    Griseofulvin (Standard) is the analytical standard of Griseofulvin. This product is intended for research and analytical applications.
    Griseofulvin (Standard)
  • HY-B0754
    Hematoporphyrin
    		≥98.0%
    Hematoporphyrin (Hematoporphyrin IX), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light.
    Hematoporphyrin
  • HY-E70318
    AMK-GX
    AMK-GX (Immobilized Penicillin G acylase) is an immobilized penicillin acylase with improved temperature and pH stability. AMK-GX has reusable performance and high recovery rates, retaining much of its original activity after 12 cycles. Among them, AMK-GX can catalyze penicillin G (PG) to generate 6-aminopenicillanic acid (6-APA) and 7-aminodeacetoxycephalosporanic acid, which are key intermediates for β-lactam antibiotics.
    AMK-GX
  • HY-B0234S2
    Estrone-d4
    		99.54%
    Estrone-d4 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells.
    Estrone-d<sub>4</sub>
  • HY-W034065
    3,5-Dihydroxyacetophenone
    		99.96%
    3,5-Dihydroxyacetophenone is an endogenous metabolite.
    3,5-Dihydroxyacetophenone
Cat. No. Product Name / Synonyms Application Reactivity