1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1427
    Gamibetal
    ≥98.0%
    Gamibetal is the gamma-amino-beta-hydroxybutyric acid. Gamibetal has the potential for the research of epilepsy.
    Gamibetal
  • HY-W015061S
    N-(Phenylacetyl-d5)glycine
    ≥99.0%
    N-(Phenylacetyl-d5)glycine is the deuterium labeled Phenylacetylglycine. Phenylacetylglycine is a gut microbial metabolite that can activate β2AR. Phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion.
    N-(Phenylacetyl-d<sub>5</sub>)glycine
  • HY-N0416R
    Cucurbitacin B (Standard)
    Cucurbitacin B (Standard) is the analytical standard of Cucurbitacin B. This product is intended for research and analytical applications. Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity.
    Cucurbitacin B (Standard)
  • HY-Y0289S1
    1-Dodecanol-d25
    98.09%
    1-Dodecanol-d25 is the deuterium labeled 1-Dodecanol. 1-Dodecanol is an endogenous metabolite.
    1-Dodecanol-d<sub>25</sub>
  • HY-P2808
    4-Phytase
    4-Phytase is a phosphohydrolase of inositol hexaphosphate.
    4-Phytase
  • HY-E70135
    Endo-β-N-acetylglucosaminidase F1
    Endo-β-N-acetylglucosaminidase F1 (Endo F1) cleaves Asparagine-linked high mannose and some hybrid oligosaccharides.
    Endo-β-N-acetylglucosaminidase F1
  • HY-W037619
    Pteridine-2,4(1H,3H)-dione
    99.86%
    Pteridine-2,4(1H,3H)-dione is an endogenous metabolite.
    Pteridine-2,4(1H,3H)-dione
  • HY-W013159S
    2'-Deoxyguanosine 5'-monophosphate-13C10,15N5 disodium
    98.97%
    2'-Deoxyguanosine 5'-monophosphate-13C10,15N5 (dGMP-13C10,15N5) disodium is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis.
    2'-Deoxyguanosine 5'-monophosphate-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>5</sub> disodium
  • HY-A0181AR
    Adenosine 5'-monophosphate monohydrate (Standard)
    Cyanidin 3-sambubioside (chloride) (Standard) is the analytical standard of Cyanidin 3-sambubioside (chloride). This product is intended for research and analytical applications. Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties.
    Adenosine 5'-monophosphate monohydrate (Standard)
  • HY-104026CS
    L-Kynurenine-13C10 sulfate hemihydrate
    99.90%
    L-Kynurenine-13C10 (sulfate hemihydrate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate hemihydrate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype.
    L-Kynurenine-<sup>13</sup>C<sub>10</sub> sulfate hemihydrate
  • HY-W019700
    PNU-100440
    99.67%
    PNU-100440 is the metabolite of Linezolid (HY-10394).
    PNU-100440
  • HY-101399R
    γ-Glu-Phe (Standard)
    Ceftezole (sodium) (Standard) is the analytical standard of Ceftezole (sodium). This product is intended for research and analytical applications. Ceftezole sodium (CTZ sodium) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole sodium (CTZ sodium) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity.
    γ-Glu-Phe (Standard)
  • HY-B0456S
    Riboflavin-13C4,15N2
    Riboflavin-13C4,15N2is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
    Riboflavin-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-107378
    L-Valyl-L-phenylalanine
    99.07%
    L-Valyl-L-phenylalanine (Valylphenylalanine; H-VAL-PHE-OH) has been reported as biocompatible polymer.
    L-Valyl-L-phenylalanine
  • HY-W017522S3
    Adipic acid-13C
    98.62%
    Adipic acid-13C (Hexanedioic acid-13C) is the 13C labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc.
    Adipic acid-<sup>13</sup>C
  • HY-164091
    Mevalonate 5-phosphate
    Mevalonate 5-phosphate is a substrate of phosphomevalonate kinase and mevalonate-5-phosphate decarboxylase.
    Mevalonate 5-phosphate
  • HY-W008385S
    H-HoArg-OH-d4
    H-HoArg-OH-d4 is a deuterium labeled H-HoArg-OH (HY-W008385). H-HoArg-OH, a homologue arginine, is a strong inhibitor of human bone and liver alkaline phosphatase.
    H-HoArg-OH-d<sub>4</sub>
  • HY-101036R
    Choline bitartrate (Standard)
    Choline (bitartrate) (Standard) is the analytical standard of Choline (bitartrate). This product is intended for research and analytical applications. Choline bitartrate is a vitamin-like essential nutrient, can affect diseases such as liver disease, atherosclerosis and neurological disorders. Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
    Choline bitartrate (Standard)
  • HY-B0722R
    Histamine dihydrochloride (Standard)
    Histamine dihydrochloride (Standard) is the analytical standard of Histamine dihydrochloride (HY-B0722). This product is intended for research and analytical applications. Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma.
    Histamine dihydrochloride (Standard)
  • HY-N0650S7
    L-Serine-d2
    L-Serine-d2 is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
    L-Serine-d<sub>2</sub>
Cat. No. Product Name / Synonyms Application Reactivity