2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0303AR
    Diphenhydramine hydrochloride (Standard)
    Diphenhydramine (hydrochloride) (Standard) is the analytical standard of Diphenhydramine (hydrochloride). This product is intended for research and analytical applications. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB).
    Diphenhydramine hydrochloride (Standard)
  • HY-P2736
    Amidase
    Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes.
    Amidase
  • HY-W674241A
    4-Ethylphenyl sulfate sodium
    4-Ethylphenyl sulfate sodium is a gut microbial metabolite. 4-Ethylphenyl sulfate sodium is also a protein-bound uremic toxin, a xenobiotic substrate, and causes endothelial dysfunction.
    4-Ethylphenyl sulfate sodium
  • HY-N2362S1
    DL-Alanine-13C-3
    		≥98.0%
    DL-Alanine-13C-3 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver.
    DL-Alanine-<sup>13</sup>C-3
  • HY-W013179
    18-Hydroxycorticosterone
    18-Hydroxycorticosterone is a corticosteroid and a derivative of corticosterone, which can lead to serious electrolyte imbalances.
    18-Hydroxycorticosterone
  • HY-129630S
    Tetrahydrocortisol-d5
    		99.19%
    Tetrahydrocortisol-d5 is the deuterium labeled Tetrahydrocortisol. Tetrahydrocortisol is cortisol metabolite. The urinary Tetrahydrocortisol/Tetrahydrocortisone ratio decreases with increasing 11β-hydroxysteroid dehydrogenase (11β-HSD) activity.
    Tetrahydrocortisol-d<sub>5</sub>
  • HY-W127369
    1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine
    		99.6%
    1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine is an endogenous metabolite present in Urine that can be used for the research of Obesity.
    1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine
  • HY-N8460
    Cortisol sulfate
    Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate is a specific ligand for intracellular transcortin.
    Cortisol sulfate
  • HY-103638AR
    3-Methoxytyramine (Standard)
    3-Methoxytyramine (Standard) is the analytical standard of 3-Methoxytyramine. This product is intended for research and analytical applications. 3-Methoxytyramine, a well known extracellular metabolite of 3-hydroxytyramine/dopamine, is a neuromodulator.
    3-Methoxytyramine (Standard)
  • HY-41417S3
    Octanoic acid-13C
    		98.15%
    Octanoic acid-13C is the 13C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
    Octanoic acid-<sup>13</sup>C
  • HY-125671
    Triarachidin
    		≥99.0%
    Triarachidin is an endogenous metabolite.
    Triarachidin
  • HY-W013495S
    Porphobilinogen-13C2
    Porphobilinogen-13C2 is the 13C-labeled Porphobilinogen. Porphobilinogen could act as a phototoxin, a neurotoxin, and a metabotoxin.
    Porphobilinogen-<sup>13</sup>C<sub>2</sub>
  • HY-W015213
    Adenine monohydrochloride hemihydrate
    		99.87%
    Adenine monohydrochloride hemihydrate is a hydrochloride derivative of Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
    Adenine monohydrochloride hemihydrate
  • HY-P2795
    Kallikrein, Porcine pancreas
    Kallikrein, Porcine pancreas (kininogenase) is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides, respectively.
    Kallikrein, Porcine pancreas
  • HY-N0169R
    Hyodeoxycholic acid (Standard)
    Hyodeoxycholic acid (Standard) is the analytical standard of Hyodeoxycholic acid. This product is intended for research and analytical applications. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells.
    Hyodeoxycholic acid (Standard)
  • HY-N6859
    Lucidenic acid LM1
    		99.90%
    Lucidenic acid LM1 is a natural triterpenoid isolated from Ganoderma lucidum.
    Lucidenic acid LM1
  • HY-W012480S1
    DL-Tryptophan-d8
    		99.64%
    DL-Tryptophan-d8 is the deuterium labeled DL-Tryptophan. DL-Tryptophan is an endogenous metabolite.
    DL-Tryptophan-d<sub>8</sub>
  • HY-W017613
    (Ethoxymethyl)benzene
    		98.27%
    (Ethoxymethyl)benzene is an endogenous metabolite.
    (Ethoxymethyl)benzene
  • HY-135024
    Phenylacetyl CoA
    Phenylacetyl CoA is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica.
    Phenylacetyl CoA
  • HY-A0070C
    Liothyronine hydrochloride
    Liothyronine hydrochloride is an active form of thyroid hormone. Liothyronine hydrochloride is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
    Liothyronine hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity