2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W049735
    N,N,O-Tridesmethylvenlafaxine
    N,N,O-Tridesmethylvenlafaxine is an endogenous metabolite.
    N,N,O-Tridesmethylvenlafaxine
  • HY-112016A
    (E/Z)-C20 Ceramide
    		99.94%
    (E/Z)-C20 Ceramide ((E/Z)-N-Arachidoyl-D-sphingosine) is the mixture of (Z)-C20 Ceramide and (E)-C20 Ceramide. (E/Z)-C20 Ceramide is a 20:0 ceramide.
    (E/Z)-C20 Ceramide
  • HY-113279R
    7-Dehydrocholesterol (Standard)
    7-Dehydrocholesterol (Standard) is the analytical standard of 7-Dehydrocholesterol. This product is intended for research and analytical applications.7-Dehydrocholesterol is biosynthetic precursor of cholesterol and vitamin D3.
    7-Dehydrocholesterol (Standard)
  • HY-N0610AS2
    Cinnamic acid-13C3
    		99.91%
    Cinnamic acid-13C3 (3-Phenylacrylic acid-13C3) is the 13C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
    Cinnamic acid-<sup>13</sup>C<sub>3</sub>
  • HY-W401531S
    (R)-3-O-Methyldopa-d3
    (R)-3-O-Methyldopa-d3 is a deuterium labeled (R)-3-O-Methyldopa, and (R)-3-O-Methyldopa is an R-enantiomer of 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of L-DOPA and dopamine.
    (R)-3-O-Methyldopa-d<sub>3</sub>
  • HY-113962S
    7α,25-Dihydroxycholesterol-d6
    7α,25-Dihydroxycholesterol-d6 is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly
    7α,25-Dihydroxycholesterol-d<sub>6</sub>
  • HY-B1431S1
    Butylparaben-13C6
    		99.75%
    Butylparaben-13C6 is the 13C labeled Butylparaben. Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.
    Butylparaben-<sup>13</sup>C<sub>6</sub>
  • HY-N0390S15
    L-Glutamine-d4
    L-Glutamine-d4 (L-Glutamic acid 5-amide-d4) is the deuterium labeled L-Glutamine (HY-N0390). L-Glutamine is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
    L-Glutamine-d<sub>4</sub>
  • HY-W010255A
    Phenylglyoxylic acid sodium
    		99.92%
    Phenylglyoxylic acid sodium (Benzoylformic acid sodium) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid sodium can be used as drug intermediate for synthesis of antineoplastic compounds.
    Phenylglyoxylic acid sodium
  • HY-N0486S12
    L-Leucine-d2
    		≥99.0%
    L-Leucine-d2 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway.
    L-Leucine-d<sub>2</sub>
  • HY-W013061S1
    Propane-1,2,3-triyl tripalmitate-13C3
    		≥98.0%
    Propane-1,2,3-triyl tripalmitate-13C3 is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
    Propane-1,2,3-triyl tripalmitate-<sup>13</sup>C<sub>3</sub>
  • HY-19528S2
    SAH-13C10
    		99.90%
    SAH-13C10 is the 13C labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM.
    SAH-<sup>13</sup>C<sub>10</sub>
  • HY-W013093R
    Uridine triphosphate trisodium salt (Standard)
    Uridine triphosphate (trisodium salt) (Standard) is the analytical standard of Uridine triphosphate (trisodium salt). This product is intended for research and analytical applications. Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors.
    Uridine triphosphate trisodium salt (Standard)
  • HY-113010
    1-Arachidoyl-sn-glycero-3-phosphocholine
    		≥99.0%
    1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).
    1-Arachidoyl-sn-glycero-3-phosphocholine
  • HY-77641S
    Cinnamoylglycine-d2
    Cinnamoylglycine-d2 is the deuterium labeled Cinnamoylglycine. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment.
    Cinnamoylglycine-d<sub>2</sub>
  • HY-113453
    11(R)-HETE
    		≥98.0%
    11(R)-HETE is a kind of arachidonic acid.
    11(R)-HETE
  • HY-P2818C
    Alkaline phosphatase, microorganism
    Alkaline phosphatase, microorganism is a membrane-bound glycoprotein. It can hydrolyze monophosphate esters at alkaline pH, releasing inorganic phosphate. Alkaline phosphatase, microorganism is also capable of dephosphorylating proteins, and the balance between protein phosphorylation and dephosphorylation plays a key role in regulating various cellular functions. Alkaline phosphatase, microorganism can regulate cell proliferation and differentiation.
    Alkaline phosphatase, microorganism
  • HY-Y0017S
    L-Norleucine-d9
    		99.81%
    L-Norleucine-d9 is the deuterium labeled L-Norleucine. L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.
    L-Norleucine-d<sub>9</sub>
  • HY-N0230S1
    β-Alanine-15N
    		≥98.0%
    β-Alanine-15N is the 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
    β-Alanine-<sup>15</sup>N
  • HY-N0391A
    L-Citrulline DL-malate
    		≥98.0%
    L-Citrulline (DL-malate) is an organic compound commonly used as a nutritional supplement. It boosts the body's production of nitrogen oxides, improves circulation and athletic performance, and reduces muscle fatigue. In addition, L-Citrulline DL-malate also plays an important role in some industrial fields, for example, it is used in the field of agriculture to enhance plant immunity.
    L-Citrulline DL-malate
Cat. No. Product Name / Synonyms Application Reactivity