2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118217R
    Cyclanilide (Standard)
    Cyclanilide (Standard) is the analytical standard of Cyclanilide. This product is intended for research and analytical applications. Cyclanilide (RPA90946) serves as a plant growth regulator that is applied to cotton during various growth stages.
    Cyclanilide (Standard)
  • HY-N0892R
    AKBA (Standard)
    AKBA (Standard) is the analytical standard of AKBA. This product is intended for research and analytical applications. AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.
    AKBA (Standard)
  • HY-15097R
    Myricetin (Standard)
    Myricetin (Standard) is the analytical standard of Myricetin. This product is intended for research and analytical applications. Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.
    Myricetin (Standard)
  • HY-N8489
    1-Methoxyphaseollidin
    		99.11%
    1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains.
    1-Methoxyphaseollidin
  • HY-B0150S2
    Nicotinamide-13C6
    		99.8%
    Nicotinamide-13C6 is the 13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
    Nicotinamide-<sup>13</sup>C<sub>6</sub>
  • HY-A0143S
    Dihomo-γ-linolenic acid-d6
    		≥99.0%
    Dihomo-γ-linolenic acid-d6 (DGLA-d6) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system.
    Dihomo-γ-linolenic acid-d<sub>6</sub>
  • HY-113377
    L-Glyceric acid
    L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2.
    L-Glyceric acid
  • HY-107377S
    Benzo[a]pyrene-d12
    		99.30%
    Benzo[a]pyrene-d12 is the deuterium labeled Benzo[a]pyrene. Benzo[a]pyrene shows lung carcinogenicity in animal models, and it is frequently used in chemoprevention studies.
    Benzo[a]pyrene-d<sub>12</sub>
  • HY-122320
    Phytosterols
    		98.00%
    Phytosterols are anticancer agents. Phytosterols can be used in research related to cardiovascular disease and cancer.
    Phytosterols
  • HY-W009390A
    4,4'-Disulfanediylbis(2-aminobutanoic acid)
    4,4'-Disulfanediylbis(2-aminobutanoic acid) is an endogenous metabolite.
    4,4'-Disulfanediylbis(2-aminobutanoic acid)
  • HY-113878
    12-OAHSA
    		≥99.0%
    12-OAHSA is a component of olive oil. 12-OAHSA has oral activity, and improves glucose homeostasis in insulin resistant obese mice.
    12-OAHSA
  • HY-W015424
    N-Methyl-DL-glutamic acid
    		≥98.0%
    N-Methyl-DL-glutamic acid is a L-Glutamic acid (HY-14608) analog with cytotoxic effects.
    N-Methyl-DL-glutamic acid
  • HY-W008807S
    Phosphoenolpyruvic acid potassium-13C2
    Phosphoenolpyruvic acid (potassium)-13C2 is the 13C labeled Phosphoenolpyruvic acid potassium (HY-W008807). Phosphoenolpyruvic acid (Phosphoenolpyruvate) potassium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid potassium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid potassium also exhibits cytoprotective and anti-oxidative properties.
    Phosphoenolpyruvic acid potassium-<sup>13</sup>C<sub>2</sub>
  • HY-123033AR
    Nicotinamide riboside chloride (Standard)
    Nicotinamide riboside (chloride) (Standard) is the analytical standard of Nicotinamide riboside (chloride). This product is intended for research and analytical applications. Nicotinamide riboside Chloride, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities[1]. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease[2].
    Nicotinamide riboside chloride (Standard)
  • HY-W015913S3
    Sodium 2-oxopropanoate-13C
    		98.90%
    Sodium 2-oxopropanoate-13C is the 13C labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS.
    Sodium 2-oxopropanoate-<sup>13</sup>C
  • HY-B2219S7
    Stearic acid-d4
    		99.80%
    Stearic acid-d4 is the deuterium labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
    Stearic acid-d<sub>4</sub>
  • HY-128454S
    Dimethyl trisulfide-d6
    Dimethyl trisulfide-d6 is deuterium labeled Dimethyl trisulfide (HY-128454). Dimethyl trisulfide is a cyanide antidote.
    Dimethyl trisulfide-d6
  • HY-P2877
    Tannase
    Tannase, also known as tanninyl hydrolase, is an enzyme that can hydrolyze ester bonds and tannic acid side bonds, releasing glucose and gallic acid, and is outstanding in clarifying wine and fruit juice.
    Tannase
  • HY-N0230S
    β-Alanine-13C3,15N
    β-Alanine-13C3,15N is the 13C- and 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
    β-Alanine-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N
  • HY-W049735
    N,N,O-Tridesmethylvenlafaxine
    N,N,O-Tridesmethylvenlafaxine is an endogenous metabolite.
    N,N,O-Tridesmethylvenlafaxine
Cat. No. Product Name / Synonyms Application Reactivity