2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0326R
    L-Methionine (Standard)
    L-Methionine (Standard) is the analytical standard of L-Methionine. This product is intended for research and analytical applications. L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity.
    L-Methionine (Standard)
  • HY-W034041
    Ir(p-F-ppy)3
    		≥98.0%
    Ir(pF-ppy)3 (Tris(2-(4-fluorophenyl)pyridine)iridium) is a compound that catalyzes photoreactions and has excellent photocatalytic activity. Ir(pF-ppy)3 can be used as a catalyst in organic reactions, especially in photocatalytic synthesis. Ir(pF-ppy)3 shows its unique advantages in promoting electron transfer and improving reaction selectivity. Ir(pF-ppy)3 is also used to improve the efficiency of displays and solar cells.
    Ir(p-F-ppy)3
  • HY-122949
    Momordicine I
    		Inhibitor
    Momordicine I is a cucurbitane-type triterpenoids. Momordicine I suppresses glioma growth by promoting apoptosis and impairing mitochondrial oxidative phosphorylation. Momordicine I inhibits glycolysis, lipid metabolism, induces autophagy in HNC cells to suppress head and neck cancer growth. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ. Momordicine I exerts its cardiovascular benefits by upregulating nitric oxide, inhibiting the activity of angiotensin-converting enzyme (ACE), activating the PI3K/Akt pathway, reducing oxidative stress and inflammation. Momordicine I inhibits AKT1, IL-6, and SRC, suggesting its potential application in type 2 diabetes.
    Momordicine I
  • HY-121471R
    Chrysoeriol (Standard)
    Chrysoeriol (Standard) is the analytical standard of Chrysoeriol. This product is intended for research and analytical applications. Chrysoeriol is a kind of natural yellow ash, which can be used for heating plants Coronopus didymus. Chrysoeriol suppresses the JAK2/STAT3, IκB/p65, and NF-κB pathways, and has strong anti-inflammatory activity.
    Chrysoeriol (Standard)
  • HY-W033277
    Tetrakis(acetonitrile)palladium(II) tetrafluoroborate
    		≥98.0%
    Tetrakis(acetonitrile)palladium(II) tetrafluoroborate (NSC 307191) acts as a potent Lewis acid and facilitates the formation of the 2:1 complex [Pd(1,2-bis(2′-pyridylethynyl)benzene)2](BF4)2 through the Sonogashira cross-coupling reaction.
    Tetrakis(acetonitrile)palladium(II) tetrafluoroborate
  • HY-113220S
    Monoisobutyl phthalic acid-d4
    		99.03%
    Monoisobutyl phthalic acid-d4 is the deuterium labeled Monoisobutyl phthalic acid. Monoisobutyl phthalic acid is a phthalate metabolite that is in human semen and in meconium.
    Monoisobutyl phthalic acid-d<sub>4</sub>
  • HY-20685S
    Palmitoylethanolamide-d4
    		≥99.0%
    Palmitoylethanolamide-d4 is the deuterium labeled Palmitoylethanolamide. Palmitoylethanolamide (Palmidrol) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.
    Palmitoylethanolamide-d<sub>4</sub>
  • HY-Y0079S1
    D-Phenylalanine-d8
    		98.28%
    D-Phenylalanine-d8 is the deuterium labeled D-Phenylalanine. D-Phenylalanine is the synthetic dextro isomer of phenylalanine. D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp. SC2014.
    D-Phenylalanine-d<sub>8</sub>
  • HY-W012980R
    Isovaleric acid (Standard)
    Isovaleric acid (Standard) is the analytical standard of Isovaleric acid. This product is intended for research and analytical applications. Isovaleric acid is an oral active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. Isovaleric acid can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders.
    Isovaleric acid (Standard)
  • HY-N0708R
    Vanillic acid (Standard)
    Vanillic acid (Standard) is the analytical standard of Vanillic acid. This product is intended for research and analytical applications. Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects.
    Vanillic acid (Standard)
  • HY-N2362S2
    DL-Alanine-d3
    		≥98.0%
    DL-Alanine-d3 is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver.
    DL-Alanine-d<sub>3</sub>
  • HY-B1008S
    4-Aminobenzoic acid-d4
    		99.53%
    4-Aminobenzoic acid-d4 is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.
    4-Aminobenzoic acid-d<sub>4</sub>
  • HY-124177A
    C14 Ceramide (d18:1/14:0)
    		≥99.0%
    C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research.
    C14 Ceramide (d18:1/14:0)
  • HY-W002773
    Methyl isovanillate
    		99.65%
    Methyl isovanillate is a secondary metabolite isolated from Vitex agnus-castus.
    Methyl isovanillate
  • HY-116133
    3-Hydroxystearic acid
    		98.25%
    3-hydroxy Stearic acid is a long-chain saturated fatty acid and can be found in C. pyloridis.
    3-Hydroxystearic acid
  • HY-107542S
    Oleoylethanolamide-d4
    		99.00%
    Oleoylethanolamide-d4 is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.
    Oleoylethanolamide-d<sub>4</sub>
  • HY-167887
    7PPD-Q
    		98.88%
    7PPD-Q is a substituted p-phenylenediamine antioxidants derivatives. 7PPD-Q has toxic to the bacterium V. fischeri (EC50 = 14.9 mg/L).
    7PPD-Q
  • HY-N0192R
    Arbutin (Standard)
    Arbutin (Standard) is the analytical standard of Arbutin. This product is intended for research and analytical applications. Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties.
    Arbutin (Standard)
  • HY-Y0504R
    Trimethylammonium chloride (Standard)
    Trimethylammonium chloride (Standard) is the analytical standard of Trimethylammonium chloride. This product is intended for research and analytical applications. Trimethylammonium chlorideIt is an endogenous metabolite that inhibits deacetylation. Trimethylammonium chlorideIs a non-competitive inhibitor of acetylcholinesterase.
    Trimethylammonium chloride (Standard)
  • HY-13765R
    6-Thioguanine (Standard)
    6-Thioguanine (Standard) is the analytical standard of 6-Thioguanine. This product is intended for research and analytical applications. 6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.
    6-Thioguanine (Standard)
Cat. No. Product Name / Synonyms Application Reactivity