2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0474R
    Tyrosol (Standard)
    Tyrosol (Standard) is the analytical standard of Tyrosol. This product is intended for research and analytical applications. Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
    Tyrosol (Standard)
  • HY-107823
    Cholesteryl acetate
    		99.41%
    Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester.
    Cholesteryl acetate
  • HY-N1238
    β-Sitostenone
    β-Sitostenone is a sterols that can be isolated from Cochlospermum vitifolium.β-Sitostenone inhibits tyrosinase activity, and has anti-melanogenic and anti-tumor activities.
    β-Sitostenone
  • HY-32004
    Coumalic acid
    		Inhibitor
    Coumalic acid is an inhibitor of human carbonic anhydrase (hCA) (KI = 0.073 μM for hCA IX; KI = 0.083 μM for hCA XII). Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavorings, fragrances and cosmetics industries, as polymer components, and pharmaceutical scaffolds. Coumalic acid displays antibronchial and antimalarial activity.
    Coumalic acid
  • HY-W008315R
    L-Allothreonine (Standard)
    L-Allothreonine (Standard) is the analytical standard of L-Allothreonine. This product is intended for research and analytical applications. L-Allothreonine (H-allo-Thr-OH) is an endogenous metabolite.
    L-Allothreonine (Standard)
  • HY-145656
    3-Oxochenodeoxycholic acid
    		99.92%
    3-Oxochenodeoxycholic acid is an endogenous metabolite that can be found in feces. 3-Oxochenodeoxycholic acid can serve as an indicator for the diagnosis of certain diseases, such as COVID-19.
    3-Oxochenodeoxycholic acid
  • HY-B1654S
    Flavin adenine dinucleotide-13C5 ammonium
    Flavin adenine dinucleotide-13C5 (FAD-13C5) ammonium is 13C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
    Flavin adenine dinucleotide-<sup>13</sup>C<sub>5</sub> ammonium
  • HY-41417S1
    Octanoic acid-d3
    		99.1%
    Octanoic acid-d3 is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
    Octanoic acid-d<sub>3</sub>
  • HY-125140
    ω-3 Arachidonic acid
    		≥99.0%
    ω-3 Arachidonic acid is a poly fatty acid that is essential for growth and development in infants. ω-3 Arachidonic acid inhibits arachidenol-CoA synthetase with Ki values of 14 µM. It also inhibited arachidenol-CoA synthetase of calf brain extract with IC50 values of about 5 µM.
    ω-3 Arachidonic acid
  • HY-126720
    N-Lignoceroyl Taurine
    		≥99.0%
    N-Lignoceroyl Taurine is an arachidonoyl amino acid and taurine conjugate with a fatty acid that can be isolated from bovine brain. N-Lignoceroyl Taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of the brain and spinal cord of wild-type and fatty acid amide hydrolase (FAAH) knockout mice. N-Lignoceroyl Taurine levels were 23-26-fold higher in FAAH-/- mice compared to wild-type mice, suggesting that FAAH utilizes N-Lignoceroyl Taurine as a substrate. However, in vitro experiments with purified FAAH showed that N-Lignoceroyl Taurine was hydrolyzed 2,000-fold slower in FAAH compared to oleoylethanolamide. N-Acyl Taurines with polyunsaturated acyl chains can activate members of the transient receptor potential (TRP) calcium channel family, including TRPV1 and TRPV4.
    N-Lignoceroyl Taurine
  • HY-113031S1
    16α-Hydroxydehydroepiandrosterone-d5
    16α-Hydroxydehydroepiandrosterone-d5 (16α-Hydroxy-DHEA-d5) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone (HY-113031).
    16α-Hydroxydehydroepiandrosterone-d<sub>5</sub>
  • HY-W014423S3
    L-Histidine-13C6,15N3 hydrochloride hydrate
    		99.53%
    L-Histidine-13C6,15N3 hydrochloride hydrate is the 13C- and 15N-labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable.
    L-Histidine-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>3</sub> hydrochloride hydrate
  • HY-W016814R
    (Z)-Aconitic acid (Standard)
    (Z)-Aconitic acid (Standard) is the analytical standard of (Z)-Aconitic acid. This product is intended for research and analytical applications. (Z)-Aconitic acid is a glutamate decarboxylase inhibitor. (Z)-Aconitic acid reduces IκB-α phosphorylation. (Z)-Aconitic acid inhibits Antigen-induced arthritis and Monosodium urate (HY-B2130A)-induced gout.
    (Z)-Aconitic acid (Standard)
  • HY-W779017
    Thymidine-13C5
    		99.90%
    Thymidine-13C5 (DThyd-13C5; NSC 21548-13C5) is 13C-labeled Thymidine (HY-N1150).
    Thymidine-<sup>13</sup>C<sub>5</sub>
  • HY-18341S2
    L-Thyroxine-13C6
    L-Thyroxine-13C6 is the 13C labeled L-Thyroxine. L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
    L-Thyroxine-<sup>13</sup>C<sub>6</sub>
  • HY-W012974R
    3-Aminoisobutyric acid (Standard)
    3-Aminoisobutyric acid (Standard) is the analytical standard of 3-Aminoisobutyric acid. This product is used for research and analytical applications. 3-Aminoisobutyric acid (β-Aminoisobutyric acid) exhibits anti-inflammatory and antioxidant effects. It increases the expression of brown fat cell-specific genes in white adipose tissue and enhances fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid alleviates insulin resistance and inflammation induced by palmitic acid or a high-fat diet in mice via the AMPK–PPARδ-dependent pathway. 3-Aminoisobutyric acid is a catabolite of thymine and valine in skeletal muscle.
    3-Aminoisobutyric acid (Standard)
  • HY-N11222
    Nonanoylcarnitine
    		99.87%
    Nonanoylcarnitine is a metabolite associated with chronic environmental exposure to polycyclic aromatic hydrocarbons (PAH) and fragmented QRS waves in acute myocardial infarction. Nonanoylcarnitine can be used as a potential biomarker for the metabolic outcome of PAH exposure and the prognosis of acute myocardial infarction.
    Nonanoylcarnitine
  • HY-W006429
    L-Uridine
    		99.81%
    L-Uridine is an enantiomer of the normal RNA constituent D-uridine. L-Uridine can be isolated from the Polyporaceae fungus Poria cocos (Schw.). L-uridine acts as a phosphate acceptor for nucleoside phosphotransferases.
    L-Uridine
  • HY-W671746
    Thevetin A
    		98.95%
    Thevetin A is a thevetia cardiac glycoside. Thevetin A can be isolated from the methanol extract of the seeds of Cascabela thevetioides.
    Thevetin A
  • HY-W052051
    N-Benzylacetamide
    		99.35%
    N-Benzylacetamide (N-Acetylbenzylamine), as an endogenous metabolite, is the major component of the plasma metabolic profile of Benznidazole (HY-B1548).
    N-Benzylacetamide
Cat. No. Product Name / Synonyms Application Reactivity