2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1945R
    DEHP (Standard)
    DEHP (Standard) is the analytical standard of DEHP. This product is intended for research and analytical applications. DEHP (Bis(2-ethylhexyl) phthalate) is a widely used plasticizer, which has orally active. DEHP can produce a wide spectrum of toxic effects on organisms including neurotoxicity, liver toxicity, immunotoxicity, and reproductive toxicity.
    DEHP (Standard)
  • HY-Y0839S
    Levulinic acid-d5
    		98.89%
    Levulinic acid-d5 is the deuterium labeled Levulinic acid. Levulinic acid is a precursor for the synthesis of biofuels, such as ethyl levulinate.
    Levulinic acid-d<sub>5</sub>
  • HY-W342092
    1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril
    		≥98.0%
    1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is a chemical agent that has the property of inhibiting enzyme activity in organisms. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is used as a potential anti-tumor agent in compound development. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril has the effect of regulating cell signaling pathways and can be used to study cell biology. 1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril is considered to be a potent compound that can exert biological activity under specific conditions.
    1,3,4,6-Tetrachloro-3α,6α-diphenylglycouril
  • HY-128425R
    N-?Carbamoyl-?DL-?aspartic acid (Standard)
    N-​Carbamoyl-​DL-​aspartic acid (Standard) (Ureidosuccinic acid (Standard)) is the analytical standard of N-​Carbamoyl-​DL-​aspartic acid (HY-128425). This product is intended for research and analytical applications. N-​Carbamoyl-​DL-​aspartic acid is a precursor of nucleic acid pyrimidines. N-​Carbamoyl-​DL-​aspartic acid has antitumor activities.
    N-?Carbamoyl-?DL-?aspartic acid (Standard)
  • HY-W007355R
    Skatole (Standard)
    Skatole (Standard) is the analytical standard of Skatole. This product is intended for research and analytical applications. Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors (AhR) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream.
    Skatole (Standard)
  • HY-W004283R
    Pentadecanoic acid (Standard)
    α-Linolenic acid (Standard) is the analytical standard of α-Linolenic acid. This product is intended for research and analytical applications. α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer.
    Pentadecanoic acid (Standard)
  • HY-113320S
    Etiocholanolone-d5
    		99.20%
    Etiocholanolone-d5 is the deuterium labeled Etiocholanolone. Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity. Etiocholanolone is a less potent?neurosteroid positive allosteric modulator?(PAM) of the GABAA?receptor than its?enantiomer form.
    Etiocholanolone-d<sub>5</sub>
  • HY-N1579R
    Pyrogallol (Standard)
    Pyrogallol (Standard) is the analytical standard of Pyrogallol. This product is intended for research and analytical applications. Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.
    Pyrogallol (Standard)
  • HY-113524R
    N-Acetyl-L-aspartic acid (Standard)
    N-Acetyl-L-aspartic acid (Standard) is the analytical standard of N-Acetyl-L-aspartic acid (HY-113524). This product is intended for research and analytical applications. N-Acetyl-L-aspartic acid is a derivative of Aspartic acid (HY-N0666) and endogenous compound. N-Acetyl-L-aspartic acid acts as an acetyl donor. N-Acetyl-L-aspartic acid is involved in brain metabolism. N-Acetyl-L-aspartic acid is used in the research of neurodegenerative diseases (such as Canavan disease).
    N-Acetyl-L-aspartic acid (Standard)
  • HY-W272217S
    Octacosane-d58
    		99.05%
    Octacosane-d58 is the deuterium labeled Octacosane. Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l.
    Octacosane-d<sub>58</sub>
  • HY-W590849
    F1874-108
    		Inhibitor 99.22%
    F1874-108 is an inhibitor of brassinosteroid biosynthesis and signal transduction.
    F1874-108
  • HY-107542S2
    Oleoylethanolamide-d2
    		≥98.0%
    Oleoylethanolamide-d2 is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.
    Oleoylethanolamide-d<sub>2</sub>
  • HY-113409R
    3-Hydroxyisovaleric acid (Standard)
    3-Hydroxyisovaleric acid (Standard) is the analytical standard of 3-Hydroxyisovaleric acid. This product is used for research and analytical applications. 3-Hydroxyisovaleric acid is a normal endogenous metabolite excreted in urine. The urinary excretion of 3-Hydroxyisovaleric acid serves as an early and sensitive indicator of biotin deficiency.
    3-Hydroxyisovaleric acid (Standard)
  • HY-W018392S
    Mono-(2-ethylhexyl) phthalate-d4
    		99.71%
    Mono-(2-ethylhexyl) phthalate-d4 is a deuterium labeled Mono-(2-ethylhexyl) phthalate (HY-W018392). Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD).
    Mono-(2-ethylhexyl) phthalate-d<sub>4</sub>
  • HY-19528R
    SAH (Standard)
    SAH (Standard) is the analytical standard of SAH. This product is intended for research and analytical applications. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM.
    SAH (Standard)
  • HY-107608S
    Leukotriene B4-d4
    		99.1%
    Leukotriene B4-d4 is the deuterium labeled Leukotriene B4. Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
    Leukotriene B4-d<sub>4</sub>
  • HY-W009444S
    5-Methyluridine-d4
    		99.96%
    5-Methyluridine-d4 is the deuterium labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids.
    5-Methyluridine-d<sub>4</sub>
  • HY-116567A
    (S)-OPC-51803
    		99.94%
    (S)-OPC-51803 is an agonist of the vasopressin V2 receptor, with activity in suppressing nocturia and urinary incontinence. (S)-OPC-51803 was evaluated in terms of biological activity and showed a stronger V2 receptor agonist effect compared to its (R)-isomer. The use of (S)-OPC-51803 may improve the patient's ability to control nocturnal polyuria.
    (S)-OPC-51803
  • HY-N0156R
    Oleanolic acid (Standard)
    Oleanolic acid (Standard) is the analytical standard of Oleanolic acid. This product is intended for research and analytical applications. Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
    Oleanolic acid (Standard)
  • HY-W006057AS17
    Sodium 3-Methyl-2-oxobutanoic acid-13C2
    		99.90%
    3-Methyl-2-oxobutanoic acid-13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli.
    Sodium 3-Methyl-2-oxobutanoic acid-<sup>13</sup>C<sub>2</sub>
Cat. No. Product Name / Synonyms Application Reactivity