2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0303AS
    Diphenhydramine-d6 hydrochloride
    		98.83%
    Diphenhydramine-d6 (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB).
    Diphenhydramine-d<sub>6</sub> hydrochloride
  • HY-W016798
    (S)-2-acetamido-4-amino-4-oxobutanoic acid
    		98.0%
    (S)-2-acetamido-4-amino-4-oxobutanoic acid is an endogenous metabolite.
    (S)-2-acetamido-4-amino-4-oxobutanoic acid
  • HY-W015815
    6-Methylnicotinamide
    		99.98%
    6-Methylnicotinamide is a nicotinamide derivative. 6-methylnicotinamide is also an endogenous metabolite and its sudden increase in the acute stages of intracerebral hemorrhage (ICH) exacerbates neurological damages in rat model. 6-Methylnicotinamide can significantly enhance the coordination effect between acylamino and undercoordinated defective Pb2+ cations. 6-Methylnicotinamide results in enhanced efficiency of perovskite solar cells to 24.33% with excellent environmental storage, heat, and light stabilities.
    6-Methylnicotinamide
  • HY-P2879A
    Cholesterol esterase, Porcine pancreas
    Cholesterol esterase, Porcine pancreas is an enzyme that hydrolyzes cholesterol ester to cholesterol and free fatty acid in the intestinal lumen. Cholesterol synthesized in the acinar cells and is stored in zymogen granules. Cholesterol esterase is also known as bile salt-stimulated lipase and carboxy ester lipasea, acts function for acceleration of cholesterol absorption.
    Cholesterol esterase, Porcine pancreas
  • HY-W018004S
    L-Homocitrulline-d3
    		98.90%
    L-Homocitrulline-d3 is the deuterium labeled L-Homocitrulline. L-Homocitrulline is metabolized to homoarginine through homoargininosuccinate via the urea cycle pathway and its metabolic abnormality could lead to Lysinuric Protein Intolerance (LPI).
    L-Homocitrulline-d<sub>3</sub>
  • HY-113164
    Vitamin K1 2,3-epoxide
    		99.99%
    Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1 (HY-N0684), which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. Vitamin K1 2,3-epoxide is involved in blood clotting.
    Vitamin K1 2,3-epoxide
  • HY-113053
    Prostaglandin A1
    		98%
    Prostaglandin A1 is a dehydration derivate of Prostaglandin E1. Prostaglandin A1 exhibits inhibitory activities against tumor growth, inflammation, virus replication, platelet aggregation and excitotoxin-induced neurons apoptosis.
    Prostaglandin A1
  • HY-113097
    3α,7α-Dihydroxycoprostanic acid
    		99.0%
    3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid.
    3α,7α-Dihydroxycoprostanic acid
  • HY-P1067
    Enterostatin(human,mouse,rat)
    		99.33%
    Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.
    Enterostatin(human,mouse,rat)
  • HY-B0315A
    Biotin-Vitamin B12
    		98.44%
    Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
    Biotin-Vitamin B12
  • HY-N4259
    Ginsenoside Ra3
    		98.24%
    Ginsenoside Ra3, isolated from Panax ginseng, possesses anti-cancer activity.
    Ginsenoside Ra3
  • HY-W750676R
    (rac./meso)-Astaxanthin (Standard)
    (rac./meso)-Astaxanthin (Standard) is the analytical standard of (rac./meso)-Astaxanthin. This product is intended for research and analytical applications. rac-Astaxanthin is a carotenoid pigment found primarily in marine animals including shrimp and salmon. It is a potent lipid-soluble antioxidant.
    (rac./meso)-Astaxanthin (Standard)
  • HY-B1449S11
    Uridine-13C9
    		99.00%
    Uridine-13C9 (β-Uridine-13C9) is a 13C9-labeled form of Uridine (HY-B1449). Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.
    Uridine-<sup>13</sup>C<sub>9</sub>
  • HY-113070
    Dihomo-γ-Linolenoyl Ethanolamide
    		99.0%
    Dihomo-γ-Linolenoyl Ethanolamide, an endocannabinoid, is a cannabinoid (CB) receptor agonist with Kis of 857 nM and 598 nM for human recombinant CB1 and CB2 receptors, respectively.
    Dihomo-γ-Linolenoyl Ethanolamide
  • HY-135882
    OMDM-6
    OMDM-6 is a hybrid agonist of vanilloid receptor type 1 (VR1, TRPV1) (EC50=75 nM) and cannabinoid receptor type 1 (CB1) (Ki=3.2 μM). OMDM-6 inhibits anandamide cellular uptake (ACU) with a Ki of 7.0 μM.
    OMDM-6
  • HY-W012382S
    N-Acetyl-L-tyrosine-d3
    		98.43%
    N-Acetyl-L-tyrosine-d3 is the deuterated form of N-Acetyl-L-tyrosine (HY-W012382). N-Acetyl-L-tyrosine is an orally active endogenous mitochondrial stress response regulator that can permeate the cell membrane by passive diffusion. N-Acetyl-L-tyrosine induces low-level reactive oxygen species (ROS) generation by transiently perturbing mitochondrial membrane potential, triggering reverse signaling to activate FoxO and Keap1 pathways. As a result, N-Acetyl-L-tyrosine enhances the expression of antioxidant enzyme genes, exerting anti-stress and cytoprotective effects. N-Acetyl-L-tyrosine can improve heat stress tolerance, inhibit tumor growth, and regulate energy metabolism. N-Acetyl-L-tyrosine can be used in the research of aging, metabolic diseases (such as diabetes), and cancer.
    N-Acetyl-L-tyrosine-d<sub>3</sub>
  • HY-W019704
    N-Acetyl-DL-methionine
    		98.73%
    N-Acetyl-DL-methionine is an endogenous metabolite.
    N-Acetyl-DL-methionine
  • HY-B2130S
    Uric acid-13C,15N3
    		99.20%
    Uric acid-13C,15N3 is the 13C-labeled and 15N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation.
    Uric acid-<sup>13</sup>C,<sup>15</sup>N<sub>3</sub>
  • HY-W046906
    (E)-Oct-2-enoic acid
    		98.33%
    (E)-Oct-2-enoic acid is an endogenous metabolite.
    (E)-Oct-2-enoic acid
  • HY-126356
    1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
    		99.9%
    1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite.
    1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
Cat. No. Product Name / Synonyms Application Reactivity